Gene Information

Name : TtJL18_1857 (TtJL18_1857)
Accession : YP_006059507.1
Strain : Thermus thermophilus JL-18
Genome accession: NC_017587
Putative virulence/resistance : Resistance
Product : response regulator with CheY-like receiver domain and winged-helix DNA-binding domain
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1724315 - 1724986 bp
Length : 672 bp
Strand : -
Note : PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal

DNA sequence :

GTGGCCACCCTGCTTCTGGTGGAGGACGAGCCCAGCCTGCGCCTGGGGTTGCGGCTGGCCCTCGAGGGGGCGGGGCACCG
GGTTTTGGAGGCGGCCACCGCGCGGGAGGCCTGGCCCCTCCTGCGGGAGGCGGAGCTCGTGGTCCTGGACTGGATGCTCC
CCGACGAGCCCGGGGTGCGCCTCCTGGACCGGATGCGCCAGGGCCCCTACGAGTCCCTCCCCGTCCTGATGCTCACGGCC
CGGGCCGGGGTGCGGGACCGGGTGGAGGGGCTTTCCCGCGGGGCCGACGACTACCTGGTGAAGCCCTTCGCCGTGGAGGA
GCTTCTGGCCCGCCTCGAGGCCCTCTTGCGCCGGGCGGGGAAGCGCAAGGTGCTGAGGCGGGGCCCCCTCCTCCTGGACC
TGGAGCGGATGGAGGCCCGCCTGGAAGGCAACCCCCTCCCCCTCACCCGGCGGGAGTTTGCCCTCCTCGCCTACCTGGCG
GAGCGGCCGGGCCGGGTCTGCACCCGGGAAGAGCTCCTGGAGGCGGTCTGGGGCCCGGACTACCTCGGCACCCCCAGGAC
CGTGGACCAGCACGTCCTCCAGCTCAGGGAGAAGCTTGGGGAGGACCCCAAGGCCCCCCGCTTCCTGGAGACGGTGCGGG
GCGTGGGGTACCGCTTCCGGGAGGAGGCGTGA

Protein sequence :

MATLLLVEDEPSLRLGLRLALEGAGHRVLEAATAREAWPLLREAELVVLDWMLPDEPGVRLLDRMRQGPYESLPVLMLTA
RAGVRDRVEGLSRGADDYLVKPFAVEELLARLEALLRRAGKRKVLRRGPLLLDLERMEARLEGNPLPLTRREFALLAYLA
ERPGRVCTREELLEAVWGPDYLGTPRTVDQHVLQLREKLGEDPKAPRFLETVRGVGYRFREEA

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
armR	AAN62112.1	putative response-regulator ArmR	Not tested	PAGI-2(C)	Protein	1e-16	44
vanRB	NP_815956.1	DNA-binding response regulator VanRB	Not tested	Not named	Protein	2e-16	42
copR	NP_460069.2	transcriptional regulatory protein YedW	Not tested	SPI-5	Protein	1e-17	42

• Homologs from CARD and BacMet (resistance genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	EU250284.1.orf4.gene	Protein	9e-26	44
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	BAC0197	Protein	5e-20	44
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	AE016830.1.gene2255.	Protein	7e-17	42
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	U35369.1.gene1.p01	Protein	7e-17	42
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	NC_002516.2.879194.p	Protein	4e-16	42
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	BAC0487	Protein	8e-18	41
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	HE999704.1.gene1528.	Protein	6e-19	41
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	AF162694.1.orf4.gene	Protein	2e-24	41

• Homologs from VFDB (virulence genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	VFG0473	Protein	4e-20	45
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	VFG1390	Protein	7e-18	43
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	VFG1389	Protein	1e-20	43
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	VFG0596	Protein	4e-18	42
TtJL18_1857	YP_006059507.1	response regulator with CheY-like receiver domain and winged-helix DNA-binding domain	VFG1386	Protein	2e-18	41