Gene Information

Name : TtJL18_1210 (TtJL18_1210)
Accession : YP_006058888.1
Strain : Thermus thermophilus JL-18
Genome accession: NC_017587
Putative virulence/resistance : Resistance
Product : Zn-dependent hydrolase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1114668 - 1116104 bp
Length : 1437 bp
Strand : +
Note : PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain

DNA sequence :
ATGATCTTTCGCCAGATCTACGAGGAAGGCCTCGCGCAGATGAGCTACCTCCTGGGCTGCGCCGCCACCGGGGAGGCCCT
GGTGGTAGACCCCAGGCGGGACGTGGACGTCTATTTGGACCTAGCCCAGTCCTTGGGCCTCCGCATCACCGCCATCGCCG
AGACCCACATCCACGCCGACTACCTCTCGGGGGCGAGGGAGCTCGCCCGGACCACGGGGGCCACCCTGTACCTCTCCGAC
GAGGGGGACGAGAACTGGAAGTACAAGGGCCTTGAGGGCTTCCCCCACATCCTCCTCAAGGACGGGGACGAGTTTAGGGT
GGGGAACATCCGCGTCCGGGCGGTCCACACCCCGGGCCACACCCCCGAGCACCTCTCCTTCCTGGTGGCGGACGGGGCGG
TGACGGACGAGCCCCTCCTTTTCCTCACGGGGGACTTCGTCTTCGTGGGGGACGTGGGCCGGCCGGACCTTTTGGAAGAG
GCGGCGGGGATCAAGGGCACGGCGGAGCCCGGGGCGAGGCGGATGTTTAGGAGCCTCAAGGAAAAGTTCCTCACCCTTCC
CGACCACGTCCAGGTCTGGCCCGGCCACGGGGCGGGCTCCGCCTGCGGCAAGGCGCTTGGGGCCCTCCCGGCCACCACCG
TGGGGTACGAACGCCGCCACGCCTGGTGGGCGGAGTACCTGGAGCGGGACGACGAGGAGGGGTTCGTGAAGGCCCTCCTC
CAGGGCCAGCCCGAGGCCCCCACCTACTTCAAGGAGATGAAGCGGCTGAACCGGGACGGGATGGCCATCCTGGGCGGCCT
TCCCCACCCGGGCCGCCTCACCCCGGCCCAGTTTGAGCGCTGGCTGAGGGAGGGGGCCATCCTCGTGGACACCCGGGACA
AGTTCGCCTTCGCCGGCGGGCACATCCCGGGGAGCATCAACATCCCCGCGGGGAAGAACTTCTCCACCTGGGCGGGCTGG
CTCCTCCCCTACGACCGCCCCCTCGTCCTCCTCGCCCGACCCGAGGAGGTGGAGGCCCTCACCCGGGCCCTCGTCCGCAT
CGGCCTGGACGAGGTGGTGGGGTACATCCCAGGGCTGGAGGGCTACGCCCAGGGCGAGCTGGAAACCGTCCCCCAGGTCA
CCGCCAAGGAGGCCAAGGAGCTCTGGGAGAAGGGGAAGGCCTTCGTCCTGGACGTGCGCGGGCGGGACGAGTACCTCGCG
GGGCACATCCCCGGGGCCCAAAACATCCACGCGGGCCGCGTCCTCGCCCACCTGGACCGGCTCCCCAAGGACAAGCCCCT
CATCGTCCACTGCGTGGGCGGGGACCGCTCCAGCACCGCCATCAGCGCCCTCCTGGCCCACGGTTTTAGAAACGCCCTGA
ACCTCACCGGGGGGATCAAGGCCTGGCGGGAGGCGGGCTTCCCCGTGGTGCAGGGCGAGGAACTGGTACAGGCCTAA

Protein sequence :
MIFRQIYEEGLAQMSYLLGCAATGEALVVDPRRDVDVYLDLAQSLGLRITAIAETHIHADYLSGARELARTTGATLYLSD
EGDENWKYKGLEGFPHILLKDGDEFRVGNIRVRAVHTPGHTPEHLSFLVADGAVTDEPLLFLTGDFVFVGDVGRPDLLEE
AAGIKGTAEPGARRMFRSLKEKFLTLPDHVQVWPGHGAGSACGKALGALPATTVGYERRHAWWAEYLERDDEEGFVKALL
QGQPEAPTYFKEMKRLNRDGMAILGGLPHPGRLTPAQFERWLREGAILVDTRDKFAFAGGHIPGSINIPAGKNFSTWAGW
LLPYDRPLVLLARPEEVEALTRALVRIGLDEVVGYIPGLEGYAQGELETVPQVTAKEAKELWEKGKAFVLDVRGRDEYLA
GHIPGAQNIHAGRVLAHLDRLPKDKPLIVHCVGGDRSSTAISALLAHGFRNALNLTGGIKAWREAGFPVVQGEELVQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB83478.1 - Not tested SCC 12263 Protein 1e-80 42
unnamed BAA86645.1 hypothetical protein Not tested Type-I SCCmec Protein 6e-80 41
SACOL0046 YP_184956.1 metallo-beta-lactamase Not tested Type-I SCCmec Protein 8e-80 41