Gene Information

Name : Spith_0435 (Spith_0435)
Accession : YP_006044436.1
Strain : Spirochaeta thermophila DSM 6578
Genome accession: NC_017583
Putative virulence/resistance : Resistance
Product : protein tyrosine phosphatase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 526420 - 526878 bp
Length : 459 bp
Strand : -
Note : PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin); COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: sta:STHERM_c04710 hypothetical protein; PFAM: Protein-tyrosine phosphatase, lo

DNA sequence : 
ATGCCCGAGAAAAAAGAAAAGATCTCCGTCCTCGTCCTCTGCACCGGCAACTCCTGTCGGAGTCAGATGGCCGAAGCCTG
GATACGCCACTTCCACGGTGATCGTATCACGGTCTACTCGGCGGGGATCGAGGCGCACGGCCTCAACCCCTATGCGGTAA
AGGTGATGGAGGAGGCGGGAGTCCCGCTTTCGGGACATGCGAGCAAGACCATAGACGAGCTCCCGGTGAAGGAATTCGAC
TACGTCATCACGGTGTGCGACCATGCGAGGGAGGCGTGTCCCTATTTCCCGGCGCGGGTGAAGGTCCTCCATCGCGGATT
CGACGATCCCCCCTCCCTCACCAGGGACGAGACCGACGAGGAGAGGCGCCTTGCGGTGTACCGCAGGGTGAGGGATGAGA
TACGGGAGTTCGCCCGCACCCTGCCGGCCTTTCTGGGCCTCTCCGACCAGGGAGCGTAA

Protein sequence : 
MPEKKEKISVLVLCTGNSCRSQMAEAWIRHFHGDRITVYSAGIEAHGLNPYAVKVMEEAGVPLSGHASKTIDELPVKEFD
YVITVCDHAREACPYFPARVKVLHRGFDDPPSLTRDETDEERRLAVYRRVRDEIREFARTLPAFLGLSDQGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsC YP_252023.1 arsenate reductase Not tested SCCmec Protein 3e-23 46
arsC YP_005754064.1 arsenate reductase Not tested Type-XI SCCmec Protein 1e-22 45
arsC YP_252016.1 arsenate reductase Not tested SCCmec Protein 3e-22 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spith_0435 YP_006044436.1 protein tyrosine phosphatase BAC0581 Protein 1e-26 53
Spith_0435 YP_006044436.1 protein tyrosine phosphatase BAC0032 Protein 2e-23 45
Spith_0435 YP_006044436.1 protein tyrosine phosphatase BAC0580 Protein 2e-23 44