Gene Information

Name : Spith_0267 (Spith_0267)
Accession : YP_006044270.1
Strain : Spirochaeta thermophila DSM 6578
Genome accession: NC_017583
Putative virulence/resistance : Virulence
Product : glutamine synthetase, type I
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 328662 - 330086 bp
Length : 1425 bp
Strand : -
Note : PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I; COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR004809; KEGG: sta:STHERM_c02830 glutamine synthetase, type 1;

DNA sequence : 
ATGATTCCAGCCAAGACACCAAAAGAGCTCATGGCCTTCGTGGAGAGGGAGAAGGTCGAGATCGTGGACTTCCGTTTCAT
GGATTTCCCGGGCCTCTGGCAGCACTTCTCCATCCCTGCCCGCGAGCTCTCCGAAAAGACCTTCGAGGAGGGGCTCGGGT
TCGACGGGTCGAGCATCCGGGGATGGCAGGCGATCAACGAGTCGGACATGCTCGTGATCCCCGTGCTCGAGAGCGCCTTC
CTCGATCCGTTCACCCAGCACAAGACCCTGGTGCTCATCTGCAACATCCACGATCCCGTGACCCACGAGGCCTACACCAA
GGACCCCCGCAACATCGCCCGCAAGGCCGAGGCCTACCTCAAGTCCTCGGGAATCGGCACCACGGCCTACTTCGGCCCCG
AGGCCGAGTTCTTCGTCTTCGACGACATCAGGTTTGACCAGACCGTGAACGCAGGCTACTACTACATCGATTCCATGGAG
GGGCGATGGAACTCGGGCCGTGAGGAGAACCCGAACCTGGGGTACAAGCCTCGCTACAAAGAAGGGTATTTCCCCGTGCC
GCCCACCGATTCGCTCCAGGACCTCCGGAGCGAGATGACGCTCATCCTCGAGAGCATCGGGGTGCCCATCGAGGCTCAGC
ACCACGAGGTGGCCACCGGAGGGCAGTGCGAGATCGACATGCGCTTCGACTCGCTCGTCACCATGGCCGACAAGCTCCTC
AAGTACAAGTACGCGATCAAGAACACGGCACGGAAGTACAACAAGACCGTGACCTTCATGCCCAAGCCCCTCTTCGGCGA
CAACGGGTCGGGGATGCACGTGCACGTCTCCATCTGGAAGGACGACAAGAACCTCTTCGCAGGGAACGGGTATGCCGGAC
TCTCCGAGACCGCCCTCTATGCGATCGGGGGTATCCTCAAGCACGCCCCCGCGATCCTCGCCTTCACCAACCCCACGACC
AACAGCTACAAGCGGCTCGTGCCGGGGTTCGAGGCGCCCGTGAACCTCGCCTACTCCAGCAGGAACCGGAGCGCGGCGAT
CCGCATCCCCATGTACTCCGACAGTCCCAAGGCGAAGCGCATCGAGTTCCGCTGTCCCGACCCCTCCTGTAACCCCTACC
TCGCCTTCTCGGCCATCCTCATGGCCGCCATCGACGGCATCCAGAACAAGATCGATCCGGGCCAGCCGCTGGACAAGAAC
ATCTACGACCTGCCGCCCGAAGAGGCCGCCCAGGTTCCACAGACACCGGGCTCGCTTCGTGAGGCCCTCAAGGCCCTCGA
GGAGGACCACGACTTCCTGCTCAAGGGAGACGTGTTCACCGAGGACGTGATCGAGACATGGATCTCCTACAAGATGCAGA
ACGAGGTGCTCGCGGTGGAGACGAGGCCCCATCCCTGGGAGTTCGCCCTCTACTACGACATCTGA

Protein sequence : 
MIPAKTPKELMAFVEREKVEIVDFRFMDFPGLWQHFSIPARELSEKTFEEGLGFDGSSIRGWQAINESDMLVIPVLESAF
LDPFTQHKTLVLICNIHDPVTHEAYTKDPRNIARKAEAYLKSSGIGTTAYFGPEAEFFVFDDIRFDQTVNAGYYYIDSME
GRWNSGREENPNLGYKPRYKEGYFPVPPTDSLQDLRSEMTLILESIGVPIEAQHHEVATGGQCEIDMRFDSLVTMADKLL
KYKYAIKNTARKYNKTVTFMPKPLFGDNGSGMHVHVSIWKDDKNLFAGNGYAGLSETALYAIGGILKHAPAILAFTNPTT
NSYKRLVPGFEAPVNLAYSSRNRSAAIRIPMYSDSPKAKRIEFRCPDPSCNPYLAFSAILMAAIDGIQNKIDPGQPLDKN
IYDLPPEEAAQVPQTPGSLREALKALEEDHDFLLKGDVFTEDVIETWISYKMQNEVLAVETRPHPWEFALYYDI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
glnA YP_003728749.1 glutamine synthetase Not tested cag PAI Protein 1e-105 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spith_0267 YP_006044270.1 glutamine synthetase, type I VFG1399 Protein 1e-132 59