Gene Information

Name : Spith_1977 (Spith_1977)
Accession : YP_006045952.1
Strain : Spirochaeta thermophila DSM 6578
Genome accession: NC_017583
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2212646 - 2213143 bp
Length : 498 bp
Strand : +
Note : PFAM: Redoxin; COGs: COG2077 Peroxiredoxin; HAMAP: thiol peroxidase; InterPro IPR013740; KEGG: sta:STHERM_c19310 thiol peroxidase; PFAM: Redoxin; SPTR: Thiol peroxidase (Atypical 2-Cys peroxiredoxin)

DNA sequence : 
ATGGCCACCGTGACACTGAAAGGCGAACCCATCCACACCGTGGGAGAACTCCCGGCCCCCGGGCAGAAGGCACCGGACTT
CCTCCTCACCACTGTGAATCTCACCGACGTGACCCTCGCCGACTTTCGGGGCAAGAAGAAGATCCTCAACATCGTGCCAA
GTCTCGACACCGGGGTGTGCGCCACCTCGGCCAAGCGCTTCAACGAAAAGGTACGGGGACGGGACGACCTCGTGGTCCTC
ACCATAAGCTGCGACCTCCCCTTCGCCCAGGAGAGATTCTGCAAGACCGAAGGGATCGACAACGTGATCACCCTCTCGCA
ACTCAGGAACAGGGAGTTCGGCACGGCCTACGGCGTGGAGATCGCAGACGGGCCGCTCGCAGGACTCCTCGCCCGCGCCG
TGGTGGTTCTCGACGAGCGCGATACCGTGGTCTACACCGAACTCGTGCCCGAGATCGCCCGGGAACCCGACTACGACGAG
GCCCTCCGCCACGTGTAG

Protein sequence : 
MATVTLKGEPIHTVGELPAPGQKAPDFLLTTVNLTDVTLADFRGKKKILNIVPSLDTGVCATSAKRFNEKVRGRDDLVVL
TISCDLPFAQERFCKTEGIDNVITLSQLRNREFGTAYGVEIADGPLAGLLARAVVVLDERDTVVYTELVPEIAREPDYDE
ALRHV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 2e-22 42
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 2e-22 42
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 1e-22 42
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 3e-22 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spith_1977 YP_006045952.1 thiol peroxidase VFG0087 Protein 5e-23 42