Gene Information

Name : Spith_1276 (Spith_1276)
Accession : YP_006045258.1
Strain : Spirochaeta thermophila DSM 6578
Genome accession: NC_017583
Putative virulence/resistance : Virulence
Product : ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1425608 - 1428118 bp
Length : 2511 bp
Strand : -
Note : PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA); COGs: COG0542 ATPase with chaperone activity ATP-binding subunit

DNA sequence :
ATGTTTAAGGATTTGACGCAGCGCGCCCAGAAGATACTCACGGTGCTCGCCCAGGATGAGGCGAAGCGGTTTCATGCGGA
AGAACTGGAGCCGGAGCATATCATCCTCGCCATCATCCGCGAAGGGGCGGGCGTTGCCTATAGAGCGATAAAACGTCTCA
AGATCGCGCCGGAGGAGATCCAGGTCTTCGTAGAGAAGAATCTCTCCAAACAGAGGGGGAGTTTCATCCTCGGGGATGTA
CCCCTTTCCTCCAGGAGCAGGAGGGTTCTCGAGTATGCAGCCGAGGAGGCCCGCCATTTGGACGACGAATACATTGGGAC
CGAGCATCTCATGCTGGGATGTGCCCGCGACGGCGAGGGGGTGTTCACCCGGTTCCTGGCCCAGAAGGGCATCGACCTGG
AAGTCTTGAGGGAGGCCATCCTCGAGGTGAAGGGGAGTGAATCGGTGTACAACAGCTCGTGGGGGGGGAAGGAGGAACAG
GAGAAACGGAGGGGGGCTTTCCAGTCGGCTGCCTACAGAAAGAATACCCCATTGCTCGACGAGTTCTCCAGGGATCTCAC
CGAGCTCGCCCGGACGGGTAAGCTCGATCCGGTCATCGGGAGGGAGCGTGAGCTTCGTCGTATCGTCCAGATCCTGGCCC
GACGCACCAAGAACAACCCCGTGCTCATCGGTGACCCGGGGGTGGGGAAGACGGCGATCGTGGAGGCTCTCGCCCAGCGG
ATCGTGCGCGGCGAGGTGCCCGAGATGCTCGAGGGCAAGCGCATACTCGTCCTCGATCTTGCGGCCCTGGTGGCGGGGAC
CAAGTACCGGGGCGAGTTCGAGGAACGGCTCAAGCGGGTGATGCGGGAGATCGTCTCGGTGAAGAACGTGGTCCTCTTCA
TCGACGAGCTCCACACCATCATTGGCGCGGGCGGTGCCGAGGGTGCCATCGACGCCTCCAACATGCTCAAGCCTGCGCTC
TCACGGGGGGAGATCCAGTGCATCGGCGCCACCACCCTGGACGAGTACCGGAAGTACATCGAAAAGGATGCGGCACTGGA
GCGCAGGTTCCAGCCCGTGTACGTTCGCGAGCCGACCATCGAGGAGACGATCCAGATCCTCGAAGGGATAAAGACGAGGT
ACGAGGATTTCCACAACGTCACCTATACGCGCAAGGCCGTGGAGGCGGCGGTGGTCCTCTCTGCTCGCTACATCACCGAA
CGCCACCTGCCCGACAAGGCCATCGATCTGCTCGACGAGGCGGGATCGCGGACCCACGTGCAGGTGCTCAACCGGCCTCA
GGAGATAGAGGAGCTTGAGAAAAAGATAGACCAGCTCAATTCCGAGAAGATCATGCTCGTGAACACGCAGAACTACGAGC
GGGCGGCTGCGGTGAGGGACCAGGTGAACCGGCTCAAGATGGAGCTCGAGAGGCTGAAGACCGCCTGGAAGCTCGAGATC
AAACGGACGCAGAACATCGTGGATCAGGAGGATATCCAGGAGGTCGTCTCCGACATCACCGGCATCCCGCTCGTGAGGAT
CGCGCAGAGTGAATCGGAGCGTCTCCTCCATATCGAGGAAGAGCTCCACCGGAAAGTGATAAGCCAGGACGAGGCCATAA
AAGTGGTGGCATCTGCCATCCGCAGGGCGCGGACGGGGCTGAGCTCTCCAAACCGTCCCATGGGGTCGTTCGTCTTCCTC
GGGCCGACCGGTGTGGGTAAGACCCTTCTCGCGAAGACCCTGGCCGAATATCTCTTCGGCGACACCTCCGCGCTCATCCG
GCTCGACATGTCGGACTTCATGGAGAAACACAACGTCTCGAGGCTCGTGGGGGCCCCTCCAGGGTATGTGGGCTACGAGG
AGGGCGGCCTCCTCACGGAGAAGGTGCGTCACAGGCCCTACTCGGTGATACTCTTCGACGAGATAGAGAAGGCTCATCCG
GATGTCTTCAACATCCTCCTTCAGATCCTCGAAGAGGGGGAACTGCAGGACAACCTGGGACACAGGGTCTCCTTCCGGAA
CGCCGTACTCATCATGACCTCGAACGCGGGTGCCAGGGAGATCACCCGCGAGTCCACGGTGGGCTTCCAGACCAAGGAAG
GGATCCTCGATTTCAGAGAGATCCAGGCCTCTGCGATGAACGAGTTGAGGCGCATCTTCCGTCCCGAGTTCCTCAACCGA
ATCGATGAGATCGTGGTGTTCAAGAGCCTCAGCAGGGCGGATCTCGAACGGATATTGGGGCTCCTCCTGGAAGAGGTGTT
CCAGCGGGTGAGGGAGCAGGGGATGGAGATAGAGATCACGAAGCGCGCTCGGGAGTATCTCCTGGACAAAGGGTATGATC
CTCGCTATGGAGCGCGACCCCTCAGGAGGACCATACAGCGCGAGCTCGAAGACCCGCTCTCCATGGAGATCCTCAGGCAG
CGTTTCGTGCCGGGATCGTACATCCTGGTGACGGTGCGGAGCGGGAAGCTCGTGTTCCAGCAGAAACAGACCAAGAAACC
CCCTGAAAAGGTGACGGTGGAGACCCGGTAG

Protein sequence :
MFKDLTQRAQKILTVLAQDEAKRFHAEELEPEHIILAIIREGAGVAYRAIKRLKIAPEEIQVFVEKNLSKQRGSFILGDV
PLSSRSRRVLEYAAEEARHLDDEYIGTEHLMLGCARDGEGVFTRFLAQKGIDLEVLREAILEVKGSESVYNSSWGGKEEQ
EKRRGAFQSAAYRKNTPLLDEFSRDLTELARTGKLDPVIGRERELRRIVQILARRTKNNPVLIGDPGVGKTAIVEALAQR
IVRGEVPEMLEGKRILVLDLAALVAGTKYRGEFEERLKRVMREIVSVKNVVLFIDELHTIIGAGGAEGAIDASNMLKPAL
SRGEIQCIGATTLDEYRKYIEKDAALERRFQPVYVREPTIEETIQILEGIKTRYEDFHNVTYTRKAVEAAVVLSARYITE
RHLPDKAIDLLDEAGSRTHVQVLNRPQEIEELEKKIDQLNSEKIMLVNTQNYERAAAVRDQVNRLKMELERLKTAWKLEI
KRTQNIVDQEDIQEVVSDITGIPLVRIAQSESERLLHIEEELHRKVISQDEAIKVVASAIRRARTGLSSPNRPMGSFVFL
GPTGVGKTLLAKTLAEYLFGDTSALIRLDMSDFMEKHNVSRLVGAPPGYVGYEEGGLLTEKVRHRPYSVILFDEIEKAHP
DVFNILLQILEEGELQDNLGHRVSFRNAVLIMTSNAGAREITRESTVGFQTKEGILDFREIQASAMNELRRIFRPEFLNR
IDEIVVFKSLSRADLERILGLLLEEVFQRVREQGMEIEITKRAREYLLDKGYDPRYGARPLRRTIQRELEDPLSMEILRQ
RFVPGSYILVTVRSGKLVFQQKQTKKPPEKVTVETR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-169 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spith_1276 YP_006045258.1 ATPase VFG0079 Protein 0.0 52
Spith_1276 YP_006045258.1 ATPase VFG0080 Protein 7e-152 52