Gene Information

Name : Spith_0122 (Spith_0122)
Accession : YP_006044126.1
Strain : Spirochaeta thermophila DSM 6578
Genome accession: NC_017583
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 148829 - 150799 bp
Length : 1971 bp
Strand : +
Note : PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; COGs: COG0021 Transketolase; InterPro IPR005474:IPR005475:IPR005476:IPR00547

DNA sequence :
ATGGACAGGAAAGCTCTGGAGAAGATAGCGCTCTCGGTACGGAGTCTCTCCATGGACGCGGTGGAGGCGGCCAAGTCGGG
ACATCCTGGCCTTCCTCTGGGTGCGGCAGAGATAGGTGCGGTGCTCTTCGGGGAGGTGCTCAGGCTCTCGCCTCATGATC
CGGCCTGGATCAATCGTGACCGGTTCGTCCTCTCGGCAGGTCATGGTTCCATGTGGCTCTACTCACTCCTCCATCTCGCC
GGTTTCGATCTCCCCTTGGACGAGATCAAACGGTTCCGCCAGCTCGGTTCCAAGACGCCGGGGCATCCGGAGTACGGTCA
CACGGCCGGGGTGGAGACCACCACGGGCCCCCTCGGGCAAGGGTTTGCGAACGCGGTGGGCATGGCCATCGCGCAGGAGA
TGCTCGCCGCCAGGTTCAACACTCCGGAGTTTCCCCTCATCGATCACTACGTGTACGCCCTTGCAGGCGACGGCTGTCTC
ATGGAGGGGGTGAGCGCAGAGGCCGCCTCACTCGCGGGGCACCTCAAGCTCGGCAGGCTCATCGTGTTCTACGATTCGAA
CCGTATCACCATAGAGGGTGAGACCGACCTCGCCTTCACCGAGGATGTGGGTGCTCGTTTCGGTGCGTATGGCTGGCAGG
TCCTGGAAGGCGACGGGTACGACATGGAGGGGATCCTCTCCCTGGTCGAGGAGGCAAAGGCCGAACGGGAACGCCCGACG
CTCATCATCCTTCACACCACGATCGGGAAAGGCGCTCCGAACAAGGCCGGTTCCCACGAGGTACACGGCGCTCCGTTGGG
GTCCGAGGAGGTGAAGGCTTCGAAACGGGCCCTGGGAATCCCCGAGGACGCGCAGTTCTACGTGGCACCCGAGGCCTACG
CCTACTTCGAGGAACGACGGAAGGCCTGGAGGGAGGAGTACGACAGGTGGCAGCGGATGTTCTCCGACTGGGCGCGCACG
TACCCCGAGAAGAAGGCGGAATGGGACAGGTTCTTCGGCCCGGTCGATCTCTCGAAGGTGAGCTTCCCCTCTTTCGAGCG
TGGGAGCAAGGTGGCGACCAGAAAGGCGAGCGGCGAGGTGCTCAAGGCCCTTGCCGCAGGTGTCCCGAACCTGGTGGGCG
GGTCCGCGGATCTCGCGCCGTCCAACAACACGGCCCTCCCCGGATATGGGGACTTCAGCGTCGGGGATCGTACGGGGAGG
ACCCTCCACTACGGGGTGAGGGAGCACGCCATGGGTGCCGTGGCGAACGGCATCGCCCTCTATGGTGGATTGAGGACCTT
CTGCGCCACCTTCCTGGTCTTTTCGGACTACATGCGTCCCCCCATCAGGCTCGCCGCCCTCATGGGGCTCCCCGTGACGT
ACATCTTCACCCACGACTCGATCTTCGTCGGAGAGGACGGCCCGACCCACCAGCCGGTGGAGCACCTGGCCTCCCTCCGT
GCCGTTCCCAACCTCCTGGTGCTGAGGCCGGGGGATGCGGAGGAGACGGTGCTGGCCTGGAGGCTCGCCATGGAGAGCGC
CTCCACCCCGGTGGTGCTCGCCCTCTCACGGCAGGGACTGCCCGTCTACGAGAAGCCTGCAGCCTGGGAAGAGGACGCAC
GGCGTGGGGCTTACGTGGTGAAGGACTGCGAGGGCACCCCCGATGTGGTGGTGGTGGCCACCGGGTCCGAGGTTTCGCTC
GCCCTTGCGGCCGCAGGAGAGGCGGAGGGAAGGCGGGTCAGGGTGGTCTCCATGCTTTCGAGGGAGCTCTTCCTCTCACA
GGACGAAGCCTTCCGGGAGAGGATCGTTCCCCGCGATGTGAGGACCGTGGTGGTGGAAGCCGGTGTGGCCCTCGGGTGGG
AGGGGTTCGTCTCCCGGAGGGACGACCTCGTCACCCTGGATCGATTCGGCCTGTCCGGTCCCGGGGGCCAGGTGGCCGAG
GCGCTCGGCCTCTCGAAGGAGCGGGTGAAGCAGAGGATCATGGGGCAATGA

Protein sequence :
MDRKALEKIALSVRSLSMDAVEAAKSGHPGLPLGAAEIGAVLFGEVLRLSPHDPAWINRDRFVLSAGHGSMWLYSLLHLA
GFDLPLDEIKRFRQLGSKTPGHPEYGHTAGVETTTGPLGQGFANAVGMAIAQEMLAARFNTPEFPLIDHYVYALAGDGCL
MEGVSAEAASLAGHLKLGRLIVFYDSNRITIEGETDLAFTEDVGARFGAYGWQVLEGDGYDMEGILSLVEEAKAERERPT
LIILHTTIGKGAPNKAGSHEVHGAPLGSEEVKASKRALGIPEDAQFYVAPEAYAYFEERRKAWREEYDRWQRMFSDWART
YPEKKAEWDRFFGPVDLSKVSFPSFERGSKVATRKASGEVLKALAAGVPNLVGGSADLAPSNNTALPGYGDFSVGDRTGR
TLHYGVREHAMGAVANGIALYGGLRTFCATFLVFSDYMRPPIRLAALMGLPVTYIFTHDSIFVGEDGPTHQPVEHLASLR
AVPNLLVLRPGDAEETVLAWRLAMESASTPVVLALSRQGLPVYEKPAAWEEDARRGAYVVKDCEGTPDVVVVATGSEVSL
ALAAAGEAEGRRVRVVSMLSRELFLSQDEAFRERIVPRDVRTVVVEAGVALGWEGFVSRRDDLVTLDRFGLSGPGGQVAE
ALGLSKERVKQRIMGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 3e-124 47
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-115 46