Gene Information

Name : ureC (STH8232_0379)
Accession : YP_006040081.1
Strain : Streptococcus thermophilus JIM 8232
Genome accession: NC_017581
Putative virulence/resistance : Virulence
Product : urease subunit alpha (urea amidohydrolase subunit alpha)
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 300200 - 301906 bp
Length : 1707 bp
Strand : +
Note : -

DNA sequence :
ATGGATCGTGAAGAGTATGCTCAACACTATGGACCAACTGTAGGGGATAGCGTACGTCTTGGAGATACCAATCTTTTTGC
AACCATTGAAAAAGACTTTACTGTTTATGGACAGGAATCTAAGTTCGGTGGCGGTAAAGTTTTGCGTGATGGTATGGGTG
TTAGTGCTACGGAAACACGTGACAATCCATCAGTTGTTGATACCATTATTACAGGTGCAACCATCATTGACTATACAGGT
ATTATTAAAGCAGATATCGGTATTCGTGATGGTAAGATTGTTGCTATTGGTCGCGGTGGTAACCCAGATACAATGGACAA
TGTGGACTTTGTTGTGGGTGCTAGTACAGAAGCCATTGCTGCAGAAGGTTTGATTGTGACTGCTGGTGGTATTGACCTCC
ACGTACATTATATTTCTGCTGACCTTCCTGAATTTGGTATGGATAATGGAATTACGACCCTCTTTGGTGGTGGTACTGGT
CCCGCTGACGGTAGTAATGCAACAACATGTACACCTGGTAAATTCCATATTACTCGTATGTTGCAAGCTGTTGATGATAT
GCCTGCTAACTTTGGTTTCCTTGCCAAAGGTGTTGGTTCTGAGACTGAAGTGGTTGAAGAGCAAATTAAAGCTGGTGCAG
CAGGAATTAAGACACACGAGGACTGGGGTGCGACTTACGCAGGAATTGATAATTCCCTTAAAGTTGCGGATAAATACGAT
GTTTCTTTTGCGGTCCACACCGACTCTTTGAATGAGGGTGGATTTATGGAAAATACTTTGGAATCTTTCCAAGGTCGTAC
CGTTCATACCTTCCATACCGAAGGTTCTGGTGGTGGGCACGCTCCAGATATTATGGTTTTTGCAGGTAAGGAAAATATTT
TGCCATCATCAACTAACCCAACTAACCCATATACTACAAATGCTATTGGTGAGTTGTTAGATATGGTTATGGTTTGTCAC
CACTTGGATCCAAAAATCCCAGAAGACGTATCTTTTGCCGAATCACGTGTTCGTAAACAAACTGTGGCTGCAGAAGATGT
TCTTCATGATATGGGAGCCCTTAGTATCATGACTTCAGACGCCATGGCAATGGGACGTGTCGGTGAAGTAGTAATGCGTT
GTTGGCAACTAGCTGATAAGATGAAGGCTCAGCGTGGTCCACTTGAAGGAGATTCAGAGTTTAACGATAATAACCGTATT
AAACGTTACGTGGCTAAATATACAATTAACCCTGCCATCACCAATGGTATTGCAGACTATATCGGTTCTGTAGAAGTTGG
TAAATTTGCAGATTTGGTTATCTGGGAACCAGCACAATTTGGTGCAAAACCTAAGTTGGTGCTTAAGGGTGGTATGTTAA
CTTATGGTGTTATGGGTGACGCTGGCTCAAGTCTTCCAACACCTCAACCACGTATCATGCGTAAATTATATGGTGCTTAT
GGTCAAGCGGTTCATAAAACAAATATTACATTTGTCTCTCAATATGCTTATGATCATGGTATCAAAGAAGAAATTGGTTT
GAATAAGATTGTTCTTCCTGTTAAGAATACGCGTAACTTGACTAAGCGTGATATGAAGCTTAATGACTACGCTCCAAAAA
CAATCCGTATCGATCCACAGACCTTTGATGTCTTTATTGATGATGAGTTGGTTACTTGTGAGCCAATCCATACGACATCA
TTGTCTCAACGTTATTTCTTGTTCTAA

Protein sequence :
MDREEYAQHYGPTVGDSVRLGDTNLFATIEKDFTVYGQESKFGGGKVLRDGMGVSATETRDNPSVVDTIITGATIIDYTG
IIKADIGIRDGKIVAIGRGGNPDTMDNVDFVVGASTEAIAAEGLIVTAGGIDLHVHYISADLPEFGMDNGITTLFGGGTG
PADGSNATTCTPGKFHITRMLQAVDDMPANFGFLAKGVGSETEVVEEQIKAGAAGIKTHEDWGATYAGIDNSLKVADKYD
VSFAVHTDSLNEGGFMENTLESFQGRTVHTFHTEGSGGGHAPDIMVFAGKENILPSSTNPTNPYTTNAIGELLDMVMVCH
HLDPKIPEDVSFAESRVRKQTVAAEDVLHDMGALSIMTSDAMAMGRVGEVVMRCWQLADKMKAQRGPLEGDSEFNDNNRI
KRYVAKYTINPAITNGIADYIGSVEVGKFADLVIWEPAQFGAKPKLVLKGGMLTYGVMGDAGSSLPTPQPRIMRKLYGAY
GQAVHKTNITFVSQYAYDHGIKEEIGLNKIVLPVKNTRNLTKRDMKLNDYAPKTIRIDPQTFDVFIDDELVTCEPIHTTS
LSQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 8e-152 58
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-151 58
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-151 58
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-151 58
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-148 57
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-148 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_006040081.1 urease subunit alpha (urea amidohydrolase subunit alpha) VFG0270 Protein 1e-144 58