Gene Information

Name : pyk (STH8232_1401)
Accession : YP_006041040.1
Strain : Streptococcus thermophilus JIM 8232
Genome accession: NC_017581
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1158136 - 1159638 bp
Length : 1503 bp
Strand : -
Note : -

DNA sequence :
ATGAATAAACGCGTAAAAATAGTTGCTACACTTGGTCCTGCGGTTGAAATCCGTGGTGGCAAGAAATTTGGTGAAGATGG
TTACTGGAGTGAAAAACTTGACCCTGATGCATCTGCTAAAAACATTGCTCAATTGATCGAGGAAGGTGCTAACGTTTTCC
GTTTCAACTTCTCACATGGTAACCACGCTGAGCAAGGTGAACGTATGGATGTCGTACGTATGGCTGAATCTATTGCTGGT
CAAAAAGTAGGTTTCCTTCTTGACACTAAGGGACCTGAAATCCGTACTGAATTGTTTGAAGGTGATGCTAAAGAGTATGC
ATACAAAACTGGTGAACAAATCCGTATTGCTACTAAACAAGGTCTCAAATCAACTCGCGACGTTATTGCTTTGAACGTTG
CTGGTGGACTTGACATTTTCGACGATGTAGAAGTTGGTAAACAAGTTCTTGTGGATGATGGTAAACTTGGTCTTCGTGTT
GTAGACAAGGATGCTGAAAAACGTGAATTCATCGTTGAGGTTGAAAATGATGGTATTATTGCTAAACAAAAAGGTGTAAA
CATCCCTTACACTAAAATTCCTTTCCCAGCACTTGCTGAACGTGATAATGCTGATATTCGTTTTGGTCTCGAACAAGGTA
TTAACTTTATCGCAATCTCATTTGTACGTACTGCGAAAGACGTACAAGAAGTACGTGCTATCTGTGAAGAAACTGGAAAC
GGCCACGTTAAATTGTTGGCTAAAATCGAAAACCAACAAGGTATCGATAATATCGATGAAATCATTGAAGCTGCTGATGG
TATCATGATCGCTCGTGGTGACATGGGTATCGAAGTACCATTCGAAATGGTTCCAGTTTACCAAAAAATGATTATCACTA
AAGTAAATGCTGCTGGTAAATTTGTTGTTACAGCTACAAACATGCTTGAAACAATGACAGAAAAACCACGTGCAACTCGT
GCTGAAGTATCTGACGTGTTTAATGCTGTTATCGATGGTACTGATGCGACAATGCTTTCTGGTGAGTCTGCAAACGGTAA
ATATCCAGTTGAATCAGTTCATACAATGGCTACAATTAATAAAAACGCTCAAGCTCTTCTTAAAGAGTATGGTCGTCTTG
ATCCATCAACATTTGATCGCTCAAGTAAAACTGAAGTTGTTGCATCTGCAGTTAAAGAAGCTACCAACTCAATGGATATC
AAACTTATTGTTGCACTTACTGAATCTGGTAACACAGCTCGTTTGATTTCTAAATACCGTCCAGAAGCTGACATCTTGGC
AGTAACATTCGATGAACTTACTCAAAAATCATTGATGCTTAACTGGGGTGTTATTCCAATTGTTACTGAAATACCTTCAT
CTACTGATGATATGTTTGAAATTGCTGAGCGTGTTGCTCTTGAATCAGGTCTTGTCGAATCAGGTGATAACATTGTTATT
GTTGCTGGTGTTCCAGTTGGTTCTGGTAATACAAATACTATGCGTATCCGCACAGTTAAATAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGEDGYWSEKLDPDASAKNIAQLIEEGANVFRFNFSHGNHAEQGERMDVVRMAESIAG
QKVGFLLDTKGPEIRTELFEGDAKEYAYKTGEQIRIATKQGLKSTRDVIALNVAGGLDIFDDVEVGKQVLVDDGKLGLRV
VDKDAEKREFIVEVENDGIIAKQKGVNIPYTKIPFPALAERDNADIRFGLEQGINFIAISFVRTAKDVQEVRAICEETGN
GHVKLLAKIENQQGIDNIDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKFVVTATNMLETMTEKPRATR
AEVSDVFNAVIDGTDATMLSGESANGKYPVESVHTMATINKNAQALLKEYGRLDPSTFDRSSKTEVVASAVKEATNSMDI
KLIVALTESGNTARLISKYRPEADILAVTFDELTQKSLMLNWGVIPIVTEIPSSTDDMFEIAERVALESGLVESGDNIVI
VAGVPVGSGNTNTMRIRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-73 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-73 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-72 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-73 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_006041040.1 pyruvate kinase VFG0479 Protein 2e-73 44