Gene Information

Name : Sbal117_4706 (Sbal117_4706)
Accession : YP_006039708.1
Strain :
Genome accession: NC_017580
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : 5.99.1.2
Position : 27905 - 30040 bp
Length : 2136 bp
Strand : +
Note : SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain, subgroup; TIGRFAM: DNA topoisomerase III, bacterial-type; KEGG: hna:Hneap_1612 DNA topoisomerase III; PFAM: DNA topoisomerase, type IA, central; Toprim do

DNA sequence :
ATGCGACTCTTTTTATGCGAAAAACCGTCACAGGCAAAAGATATTGCGAGTGTCCTTGGTTGTAAGCGTGGAGATGGTGT
TTTTACTGGTGACGGTATTGCGGTGACGTTTTGCGTTGGTCATGTTTTACAACAAGCAGAACCTGAAAACTATAACCCTG
ATTTTGAGACGTGGAATATCGTTGATTTACCCATTATCCCAACAGTTTGGAAAATGTTAGTCAGTCCAAAAACGAAAGCG
CAATTTGCGATTGTAAAAAAGCAATTGGCCAAGGCCACTGAGGTTATTATTGCAACGGATGCAGACCGCGAAGGTGAAGT
TATCGCCCGTGAGGTGCTTGAATACGTTAACTATAAAGGGCCCATTCAACGGTTGTGGCTAAGTGCGTTGGATGACGCCA
GCATTAAGAAAGCGTTGGCGTCTTTGCGACCTAACCATGAAACTGCCAAGCTTTACGATGCAGGGTTAGGCCGAAGTCGG
GGAGACTGGCTTATTGGAATGAATATGACGCGATTATGCACCTTACTGAGCCGTGAATACGGTTATCAAGGTGCATTCTC
AGTCGGAAGAGTGCAGACGCCAACATTACGGCTTGTGGTCGATAGAGATAGGCAAGTTGAGCAGTTTGAACCACAGTCGT
ATTACGATATCACTGGCTTATTTAATGCAACGATCCCGTTTAAAGCCAAATGGCAAGTGCCTGATAATCTTGGGGATGAG
CAAGGCCGCTGCTTACAAGTGACGACTGTTGATCATGTCTTGTCTCAATGTCGTGACCAACCTGGTACAGTCACGCAATT
CGATACCAAGCGGCAAAAATCTAAACACCCACCGTTATTTTTCTTAGGTTCTTTGCAAAAGGCCATGTCTGCTAAGTTTG
GCTATGGCGCTAAAGAAGTACTCGATATTGCGCAATCTTTATATGAGAAATATAAGGTCACAACTTACCCCCGAACAGAT
TGTCCTTATTTACCCTTATCTCAGAAGAAGGAGGTTGGCTCAATACTCGATAAACTCAAGGTTGTACCTACATTTGCTGC
ATGGTGTAGCGTTGCAGATGTAAATGAAACAAGTGCCTGTTGGAATGATAAGAAAATTACGGCTCACCACGGGATTATTC
CATTACCGGTGACACCGAAATTGCATGAAATGAACGAAAAGGAGCTGAATCTTTATCATGCCATTGTGCAGCGATATCTC
GCGCAGTTTTACCCAGTAGCGGAAGACGATGCCACAACAATTGAACTGATGGTTGGAAGCCAAAGTTTTAAAGCGACGGG
CAAGGTTGAGCGAGTAAAAGGCTGGCGCTTGGTGACAGGTAAAGACAGTGAGGATGAAACTGCCGATGACAGTTCTAATT
TACCGCTGTTGAGCATCGGACAAACCTTAACAGCACAGTTTCAGCGAGAAGATAAGCGAACAAAGCCACCTGGACGTTTT
ACGGAAGGAACGCTGATTGATGCAATGTCAAATATCGCTAAATTTGAAAGTGATCCCAAACTCAAATCCATTTTAAAAGA
AACCTCAGGCATTGGTACCGAAGCAACCCGAGCAAACATTATCGATACGCTCAAAGCGCGGGGATTTGTCACTGTTACGG
GGAAGCAGTTGATAAGCTCAGAAGCCGGAAGATCACTCATCGATGCGTTGCCAGATGTGCTCACCAGACCAGCTATGACA
GCATTGTGGGAACAAGCACTCGATGAGATTGCATTGGGTAATGGTTCACTGGATGATTTCATGGCAAGGCAAAGTACATT
TATCACGCAATTAGTCTCTATGTTCAAACAAGGGCAATACACATTAAAGCTGCCAAAGGTTTTGGCTGTGACACTCCCGT
GCCCAGTATGTCAAAAATCGATGAAACAATTGTCGGGGAAAAGCGGTAAGTTCTGGGTATGCGAGGACAAAGAACAATGT
GGTCTATTGCTTAATGATGAGCGCGGGAAATTGCCTAAAACAACACCTTGTACATGTAAGAAAGGGGTGCTTGTTAGAAA
AAAAGCCAAAACGAAAGGTAAGTTCTGGTGGGGATGTTCGGCATATCAATCAGGTTGCCAGCGACGATTGTTTGATAATG
AGGGTAAGCCTGGTAAAGATATGCCTAAATCCAGTCTCAATACTGTGAACCCGTGA

Protein sequence :
MRLFLCEKPSQAKDIASVLGCKRGDGVFTGDGIAVTFCVGHVLQQAEPENYNPDFETWNIVDLPIIPTVWKMLVSPKTKA
QFAIVKKQLAKATEVIIATDADREGEVIAREVLEYVNYKGPIQRLWLSALDDASIKKALASLRPNHETAKLYDAGLGRSR
GDWLIGMNMTRLCTLLSREYGYQGAFSVGRVQTPTLRLVVDRDRQVEQFEPQSYYDITGLFNATIPFKAKWQVPDNLGDE
QGRCLQVTTVDHVLSQCRDQPGTVTQFDTKRQKSKHPPLFFLGSLQKAMSAKFGYGAKEVLDIAQSLYEKYKVTTYPRTD
CPYLPLSQKKEVGSILDKLKVVPTFAAWCSVADVNETSACWNDKKITAHHGIIPLPVTPKLHEMNEKELNLYHAIVQRYL
AQFYPVAEDDATTIELMVGSQSFKATGKVERVKGWRLVTGKDSEDETADDSSNLPLLSIGQTLTAQFQREDKRTKPPGRF
TEGTLIDAMSNIAKFESDPKLKSILKETSGIGTEATRANIIDTLKARGFVTVTGKQLISSEAGRSLIDALPDVLTRPAMT
ALWEQALDEIALGNGSLDDFMARQSTFITQLVSMFKQGQYTLKLPKVLAVTLPCPVCQKSMKQLSGKSGKFWVCEDKEQC
GLLLNDERGKLPKTTPCTCKKGVLVRKKAKTKGKFWWGCSAYQSGCQRRLFDNEGKPGKDMPKSSLNTVNP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 3e-135 49
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 2e-137 48
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 1e-135 47
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 2e-135 47
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 2e-135 47
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 2e-138 47
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 1e-129 45
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 5e-132 45
topB AAW83109.1 TopB Not tested GGI Protein 2e-118 42