Gene Information

Name : Sbal117_4782 (Sbal117_4782)
Accession : YP_006035239.1
Strain :
Genome accession: NC_017578
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : 5.99.1.2
Position : 6752 - 8875 bp
Length : 2124 bp
Strand : -
Note : SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain, subgroup; TIGRFAM: DNA topoisomerase III, bacterial-type; KEGG: hna:Hneap_1612 DNA topoisomerase III; PFAM: DNA topoisomerase, type IA, central; Toprim do

DNA sequence :
ATGAGACTCTTTTTATGCGAAAAACCGTCACAGGCAAAAGATATTGCGAGTGTCCTTGGTTGTAAGCGTGGAGATGGTGT
TTTTACTGGTGACGGTATTGCGGTGACGTTTTGCGTTGGTCATGTTTTACAACAAGCAGAACCTGAAAACTATAACCCTG
ATTTTGAGACGTGGAATATCGTTGATTTACCCATTATTCCAACAGCTTGGAAAATGTTAGTCAGTCCAAAAACGAAAGCG
CAATTTGCGATTGTAAAAAAGCAATTGGCCAAGGCCACTGAGGTTATTATTGCAACGGATGCAGACCGCGAAGGTGAAGT
TATCGCCCGTGAGGTGCTTGAATACGTTAACTATAAAGGGCCCATTCAACGGTTGTGGCTAAGTGCGTTGGATGACGCCA
GCATTAAGAAAGCGTTGGCGTCTTTGCGACCTAACCATGAAACTGCCAAGCTTTACGATGCAGGGTTAGGCCGAAGTCGG
GGAGACTGGCTTATTGGAATGAATATGACGCGATTATGCACCTTACTGAGCCGTGAATACGGTTATCAAGGTGCATTCTC
AGTCGGAAGAGTGCAGACGCCAACATTACGGCTTGTGGTCGATAGAGATAGCCAAGTTGAGCAGTTTGAACCACAGTCGT
ATTACGATATCACTGGCTTATTTAATGCAACGATCCCGTTTAAAGCCAAATGGCAAGTGCCTGATAATCTTGGGGATGAG
CAAGGCCGCTGCTTACAAGTGACGACTGTTGATCATGTCTTGTCTCAATGTCGTGACCAACCTGGTACAGTCACGCAATT
CGATACCAAGCGGCAAAAATCTAAACACCCACCGTTATTTTTCTTAGGTTCTTTGCAAAAGGCCATGTCTGCTAAGTTTG
GCTATGGCGCTAAAGAAGTACTCGATATTGCGCAATCTTTATATGAGAAATATAAGGTCACGACTTACCCCCGAACAGAT
TGTCCTTATTTGCCCTTATCTCAGAAGGAGGAGGTTGGCTCAATCCTCGATAAACTCAAGGTTGTGCCAGCATTTGCTGC
ATGGTGTAGCGCTGCAGATGTAAATGAAACAAGTGCCTGTTGGAATGATAAGAAAATTACGGCTCACCACGGGATTATTC
CATTACCGGTGACACCGAAATTGCATGAAATGAACGAAAAGGAGCTGAATCTTTATCATGCTATTGTGCAGCGATATCTC
GCTCAGTTTTACCCAGTAGCGGAAGACGATGCCACAACAATTGAACTGATGGTTGGAAGCCAAAGTGTTAAAGCGACGGG
CAAGGTTGAGCGAGTGAAAGGCTGGCGCTTGGTGACAGGTAAAGACAGTGAGGATGAAACTACCGATGACAGTGCTAATT
TGCCGCTGTTGAGCATCGGACAAACCTTAACAGCACAGTTTCAGCGAGAAGATAAGCGAACAAAGCCACCTGGACGTTTT
ACGGAAGGAACGCTGATTGATGCAATGTCAAATATCGCTAAATTTGAAAGTGATCCCAAACTCAAATCCATTTTAAAAGA
AACCTCAGGCATTGGTACTGAAGCAACCCGAGCAAACATTATCGATACGCTCAAAGCGCGGGGATTTGTCACTGTTACGG
GGAAGCAGTTGATAAGCTCAGAAGCCGGAAGATCACTCATCGATGCGTTGCCAGATGTGCTCACCAGACCCGCTATGACA
GCATTGTGGGAACAAGCACTCGATGAGATTGCATTGGGTAATGGTTCACTGGATGATTTCATGGCAAGGCAAAGTACATT
TATCACGCAATTAGTCTCTATGTTCAAACAAGGGCAATACACATTAAAGCTGCCAAAGGTTTTGGCTGTGACACTCCCGT
GCCCAGTATGTCAAAAATCGATGAAACAATTGTCGGGGAAAAACGGTAAGTTCTGGGTATGCGAGGACAAAGAACAATGT
GGTCTATTGCTTAATGATGAGCGCGGGAAATTGCCTAAAACAACACCTTGTACATGTAAGAAAGGGGTGCTTGTTAGAAA
AAAAGCCAAAACGAAAGGTAAGTTCTGGTGGGGATGCTCGGCATATCAATCAGGTTGCCAGCGACGATTGTTTGATAATG
AGGGTAAGCCTGGTAAGGAGATGGAGAGCAATAACCAAACATAG

Protein sequence :
MRLFLCEKPSQAKDIASVLGCKRGDGVFTGDGIAVTFCVGHVLQQAEPENYNPDFETWNIVDLPIIPTAWKMLVSPKTKA
QFAIVKKQLAKATEVIIATDADREGEVIAREVLEYVNYKGPIQRLWLSALDDASIKKALASLRPNHETAKLYDAGLGRSR
GDWLIGMNMTRLCTLLSREYGYQGAFSVGRVQTPTLRLVVDRDSQVEQFEPQSYYDITGLFNATIPFKAKWQVPDNLGDE
QGRCLQVTTVDHVLSQCRDQPGTVTQFDTKRQKSKHPPLFFLGSLQKAMSAKFGYGAKEVLDIAQSLYEKYKVTTYPRTD
CPYLPLSQKEEVGSILDKLKVVPAFAAWCSAADVNETSACWNDKKITAHHGIIPLPVTPKLHEMNEKELNLYHAIVQRYL
AQFYPVAEDDATTIELMVGSQSVKATGKVERVKGWRLVTGKDSEDETTDDSANLPLLSIGQTLTAQFQREDKRTKPPGRF
TEGTLIDAMSNIAKFESDPKLKSILKETSGIGTEATRANIIDTLKARGFVTVTGKQLISSEAGRSLIDALPDVLTRPAMT
ALWEQALDEIALGNGSLDDFMARQSTFITQLVSMFKQGQYTLKLPKVLAVTLPCPVCQKSMKQLSGKNGKFWVCEDKEQC
GLLLNDERGKLPKTTPCTCKKGVLVRKKAKTKGKFWWGCSAYQSGCQRRLFDNEGKPGKEMESNNQT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 9e-135 49
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 4e-136 48
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 2e-134 47
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 2e-134 47
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 1e-134 47
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 6e-138 46
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 4e-129 45
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 4e-132 45
topB AAW83109.1 TopB Not tested GGI Protein 6e-117 42