Gene Information

Name : covR (SGGB_1813)
Accession : YP_006034628.1
Strain : Streptococcus gallolyticus ATCC 43143
Genome accession: NC_017576
Putative virulence/resistance : Virulence
Product : two-component system, response regulator CovR/CsrR
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1863291 - 1863983 bp
Length : 693 bp
Strand : -
Note : functional classification: COG0745(T)

DNA sequence : 
ATGAGTAAAAAGATTTTAATTATTGAAGATGAAAAAAATCTTGCACGCTTTGTGTCTTTGGAGTTACAACACGAAGGTTA
TTCTGTAGTTGTAGAAACAAACGGGCGCTTAGGGCTTCAAACGGCTCTTGATGACGATTTTGACTTGATTTTGCTTGATT
TAATGCTTCCAGATATGGATGGATTTGAAATCACGCGTCGTCTTCGATTGGAAAAAGAAACTTCTATTATTATGATGACA
GCTCGCGACTCTATTATGGATATTGTTGCTGGGCTTGATCGTGGTGCAGATGACTATATTGTCAAACCATTTGCAATTGA
AGAACTCTTGGCTCGTGTTCGTGCTGTTTTCCGCCGTCAAGATGTTGAATCTAAACGTGAACAAGACAGTCAAGGAAAAG
AAGGATTGCTTGGTCTACGCTTAAATCCTCAAAATCGTTCAGCGGTTCGAGGTGATGATGAAATTTCGCTTACAAAACGT
GAGTACGATTTGTTAAGTGTTCTTTTGTCAAATGTTAATCGTGTAATGACACGTGAAGAACTGCTAGCCAGTGTTTGGAG
ATACGATACAGATATTGAGACAAATGTTGTTGATGTTTATATCCGTTACCTTCGCGGAAAAGTCGATATTCCAGGTAAAG
AATCTTACATTCAAACAGTTCGTGGAATGGGATACATTATTCGAGAAAAATAA

Protein sequence : 
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKETSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDVESKREQDSQGKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKVDIPGKESYIQTVRGMGYIIREK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 2e-24 44
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 6e-24 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
covR YP_006034628.1 two-component system, response regulator CovR/CsrR HE999704.1.gene1528. Protein 2e-44 57
covR YP_006034628.1 two-component system, response regulator CovR/CsrR AE015929.1.gene1106. Protein 2e-37 53
covR YP_006034628.1 two-component system, response regulator CovR/CsrR NC_010079.5776364.p0 Protein 8e-39 52
covR YP_006034628.1 two-component system, response regulator CovR/CsrR NC_002952.2859858.p0 Protein 8e-39 52
covR YP_006034628.1 two-component system, response regulator CovR/CsrR NC_007622.3794948.p0 Protein 8e-39 52
covR YP_006034628.1 two-component system, response regulator CovR/CsrR NC_003923.1003417.p0 Protein 8e-39 52
covR YP_006034628.1 two-component system, response regulator CovR/CsrR NC_013450.8614146.p0 Protein 8e-39 52
covR YP_006034628.1 two-component system, response regulator CovR/CsrR NC_002951.3238224.p0 Protein 8e-39 52
covR YP_006034628.1 two-component system, response regulator CovR/CsrR NC_007793.3914065.p0 Protein 8e-39 52
covR YP_006034628.1 two-component system, response regulator CovR/CsrR NC_002758.1121390.p0 Protein 8e-39 52
covR YP_006034628.1 two-component system, response regulator CovR/CsrR NC_012469.1.7685629. Protein 6e-29 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
covR YP_006034628.1 two-component system, response regulator CovR/CsrR VFG0596 Protein 7e-25 44
covR YP_006034628.1 two-component system, response regulator CovR/CsrR VFG1390 Protein 8e-31 41