Gene Information

Name : guaA (SGGB_1040)
Accession : YP_006033868.1
Strain : Streptococcus gallolyticus ATCC 43143
Genome accession: NC_017576
Putative virulence/resistance : Unknown
Product : bifunctional GMP synthase/glutamine amidotransferase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1077816 - 1079378 bp
Length : 1563 bp
Strand : +
Note : functional classification: COG0518(F),COG0519(F)

DNA sequence :
ATGACTGACAATTCTAGTTTGAATGATGTTCAAAAAATCATTGTTCTTGATTATGGTAGCCAGTACAACCAATTGATTGC
ACGTCGTATCCGTGAATTTGGTGTGTTCTCAGAATTGAGAAGCCACAAAATCACAGCAGAAGAAGTGCGTGCGATTAACC
CAATTGGTATCGTACTTTCAGGTGGTCCAAATTCAGTTTATGCTGACAATGCCTTTGGTATTGATGAAGAAATTTTTGAA
TTGGGTATTCCAATTCTTGGTATCTGCTATGGTATGCAATTGTTGACTGACAGACTTGGTGGTAAAGTTGTTCCAGCAGG
TCAAACTGGTAACAGCGAATACGGTCAATCAACACTTCGCTTAAAAGCAAATTCAAAATTATTTGCTGACACACCAGATG
AACAAACCGTTTTAATGAGCCACGGTGATGCAGTTACCGAAATTCCAGCAGGTTTCCACCTCGTTGGTGATTCTGCTGAT
TGCCCTTACGCAGCCATTGAAAATACTGAGAAAAACATTTATGGTATCCAATTCCACCCAGAAGTTCGTCACTCAGTATA
TGGTAATGATATTTTACGTAACTTTGCTTTCAAGATTTGTGGAGCTAAAGGTGATTGGTCAATGGATAATTTCATTGATT
TGCAAATTTCTGAAATTCGCAAAAAAGTTGGAGACCGTAAAGTTCTTTTAGGACTTTCAGGTGGTGTTGATTCATCAGTT
GTTGGTGTTCTTCTTCAACGTGCTATCGGTGACCAATTGACATGTATCTTCGTTGACCATGGTCTTCTTCGTAAAGGAGA
AGGGGACCAAGTTATGAATATGCTTGGTGGTAAATTCGGATTGAACATCATTCGTGTTGATGCTTCAAAACGTTTCTTAG
ACCTTCTTGCTGGTGTTGATGACCCAGAGAAAAAACGTAAAATCATTGGTAATGAATTTGTCAGTGTATTTGATGACGAA
GCAAGCAAACTTAAAGGTGTTGACTTCTTAGCACAAGGTACTCTTTACACAGACGTTATCGAGTCTGGTACAGATACTGC
TCAAACAATCAAATCACACCACAACGTTGGTGGTCTCCCAGAAGATATGCAATTTGAATTGATTGAGCCACTTAACACAC
TTTTCAAAGATGAAGTTCGTGCGCTTGGTACAGCTCTTGGTATGCCAGATGAAATCGTTTGGCGCCAACCATTCCCAGGA
CCAGGACTTGCTATCCGTGTTATGGGTGAAATCACAGCTGAACGTCTTGAAACTGTTCGTGAATCTGACGCTATCCTTCG
TGAAGAAATTGCTAAAGCAGGTCTTGACCGCGACATCTGGCAATATTTCACTGTTAACACAGGTGTTCGTTCAGTTGGTG
TTATGGGCGACGGACGTACTTACGATTACACAATCGCAATCCGCGCTATCACATCAATCGACGGAATGACAGCAGACTTT
GCACGTATCCCATGGGATGTACTTCAAAAAATTTCAGTCCGTATCGTAAACGAAGTTGACCACGTCAACCGCATCGTCTA
TGACATCACAAGTAAACCACCAGCAACAGTGGAGTGGGAGTAG

Protein sequence :
MTDNSSLNDVQKIIVLDYGSQYNQLIARRIREFGVFSELRSHKITAEEVRAINPIGIVLSGGPNSVYADNAFGIDEEIFE
LGIPILGICYGMQLLTDRLGGKVVPAGQTGNSEYGQSTLRLKANSKLFADTPDEQTVLMSHGDAVTEIPAGFHLVGDSAD
CPYAAIENTEKNIYGIQFHPEVRHSVYGNDILRNFAFKICGAKGDWSMDNFIDLQISEIRKKVGDRKVLLGLSGGVDSSV
VGVLLQRAIGDQLTCIFVDHGLLRKGEGDQVMNMLGGKFGLNIIRVDASKRFLDLLAGVDDPEKKRKIIGNEFVSVFDDE
ASKLKGVDFLAQGTLYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEIVWRQPFPG
PGLAIRVMGEITAERLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADF
ARIPWDVLQKISVRIVNEVDHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-173 70
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-174 70
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-173 69
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-121 52