Gene Information

Name : pyk (SGGB_0979)
Accession : YP_006033809.1
Strain : Streptococcus gallolyticus ATCC 43143
Genome accession: NC_017576
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1015786 - 1017288 bp
Length : 1503 bp
Strand : +
Note : functional classification: COG0469(G)

DNA sequence :
ATGAATAAACGCGTAAAAATCGTTGCAACACTTGGTCCTGCGGTAGAACTCCGCGGTGGTAAAAAATTCGGTGAAGATGG
ATATTGGGGTGAAAGCCTTGATGTTGAAGCATCAGCTCAAAAAATCGCTGAATTGATTAAAGAAGGTGCAAACGTCTTCC
GTTTCAACTTCTCACACGGTGACCACGCAGAACAAGGTGAACGTATGGCAACTGTACGTCGTGCAGAAGAAATTGCTGGT
CAAAAAGTTGGTTTCCTTCTTGACACTAAAGGTCCAGAAATCCGTACTGAACTTTTTGAAGGTGATGCTAAAGAATATTC
ATACAAAACTGGTGAAAAAATCCGTGTTGCTACTAAACAAGGTATCAAATCAACTCGTGAAGTTATCGCATTGAACGTTG
CTGGCGCTCTTGACATCTACGATGATGTTGAAGTTGGTAAACAAGTTCTTGTTGATGATGGTAAACTTGGTCTTCGTGTT
ATTGCTAAAGATGATGCAACTCGTGAATTCGAAGTTGAAGTTGAAAACGATGGTATCATCGCTAAACAAAAAGGTGTAAA
CATTCCTTACACTAAAATCCCATTCCCAGCTCTTGCTGATCGTGACAACGCTGATATCCGTTTCGGTCTTGAACAAGGTC
TTAACTTTATCGCTATCTCATTCGTACGTACTGCAAAAGACGTTAACGAAGTTCGTGCTATCTGTGAAGAAACTGGTAAC
GGACACGTTCGTTTGTTCGCTAAAATCGAAAACCAACAAGGTATTGACAACATTGATGAAATCATCGAAGCTGCTGACGG
TATCATGATTGCTCGTGGTGATATGGGTATCGAAGTACCATTCGAAATGGTTCCAGTTTACCAAAAAATGATTATCACTA
AAGTTAATGCAGCTGGTAAAGCAGTTATCACAGCAACTAACATGCTTGAATCAATGACTGACAAACCACGTGCTACTCGT
TCTGAAGTATCTGACGTATTCAACGCTGTTATCGATGGTACTGATGCAACTATGCTTTCAGGTGAATCTGCAAACGGTAA
ATACCCAGTTGAAGCTGTTCGTGCAATGGCTACAATTGATAAAAACGCTCAAACTCTTCTTAACGAATACGGACGTCTTG
ATTCATCATCATTCGCTCGTACTTCTAAAACAGAAGTTGTGGCTTCAGCAGTTAAAGATGCAACAAGCTCAATGGATATT
AAACTTGTCGTAGCTCTTACTGAATCTGGTAACACTGCTCGTCTTATCTCTAAATACCGTCCAGATGCTGACATCTTGGC
TGTAACATTTGACGAAAAAACTCAAAAATCACTTATGATTAACTGGGGTGTTATTCCAGTTGTAACTGAAAAACCTGCAT
CAACTGATGACATGTTTGAAGTTGCTGAAAAAGCTGCCCTTGAATCAGGATTGGTTCAATCAGGTGATAACATCGTTATC
GTCGCTGGTGTTCCAGTTGGTTCAGGTGGTACAAACACAATGCGTATCCGCACTGTAAAATAA

Protein sequence :
MNKRVKIVATLGPAVELRGGKKFGEDGYWGESLDVEASAQKIAELIKEGANVFRFNFSHGDHAEQGERMATVRRAEEIAG
QKVGFLLDTKGPEIRTELFEGDAKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGKQVLVDDGKLGLRV
IAKDDATREFEVEVENDGIIAKQKGVNIPYTKIPFPALADRDNADIRFGLEQGLNFIAISFVRTAKDVNEVRAICEETGN
GHVRLFAKIENQQGIDNIDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKAVITATNMLESMTDKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVEAVRAMATIDKNAQTLLNEYGRLDSSSFARTSKTEVVASAVKDATSSMDI
KLVVALTESGNTARLISKYRPDADILAVTFDEKTQKSLMINWGVIPVVTEKPASTDDMFEVAEKAALESGLVQSGDNIVI
VAGVPVGSGGTNTMRIRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-70 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-71 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-71 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-71 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_006033809.1 pyruvate kinase VFG0479 Protein 2e-71 44