Gene Information

Name : lukS-I (SPSE_0991)
Accession : YP_006015105.1
Strain : Staphylococcus pseudintermedius ED99
Genome accession: NC_017568
Putative virulence/resistance : Virulence
Product : synergohymenotropic toxin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1018658 - 1019590 bp
Length : 933 bp
Strand : -
Note : identified by match to protein family HMM PF07968, match to protein family HMM TIGR01002

DNA sequence :
ATGGTAAAAAATAAATTATTAGCCGCAACACTATCTATAAGTTTAGTTCTTCCACTTATTACCCCATACAGTGAAGAAGC
CAAAGCTGCAAACACTATAGAAGAAATCGGCGAAGGAGCACAAATTATTAAAAGAACTGAGGATGTAAGCAGCAGAAAAT
GGGGCGTTACTCAAAACATTCAGTTTGACTTTGTTAAAGACCCTAAATACAACAAAGATGCATTAATTATTAAAATGCAA
GGTTTTATCAAATCTAGAACAAGTTTTACTGATGTTAAAGGGAAAGGATATGAATCAACAAAAAGAATGCTTTGGCCTTT
TCAATATAATATTGCTCTAAAAACAAATGATCCTAATGTCTCTTTAATTAATTATCTCCCTAAAAATAAAATTGAATCAA
TAGATGTGAGCCAAACATTAGGTTACAATGTTGGCGGTAACTTCCAAAGTGCACCATTACTTGGGGGTAAAGGCGCATTT
AATTATTCAAAGAAAATTAGCTATACTCAAAAGAATTATATTAGTGAAGTCGCACAACAAAATTCAAAAAATATCAGATG
GGAAGTCAAAGCAAATTCATTTAATACAGAAAATGGACAAGTATCAGCATATGACAGACACTTATTTGTACGAAGTCCTA
TCGGGCCAAATGCAAGAGACTTTTTTGTGCCAAATGATGAGTTACCTCCTTTAATTCAAAGTGGTTTTAATCCATCGTTT
ATTGCAACTGTATCTCATGAAAAAGATAAAGGTGATACAAGTGAATTCGAAATTGCTTATGGTAGAAATCTAGACATTAC
GTATGCAACTTTCTTCCCAAGAACTGGCATATTTGCTGAAAGACGTCATAATGCTTTAATGAATCGAAATCTTGTCACTA
AATATGAAGTGAACTGGAAAACACACGAAATTAAAGTAAAGGGGCATAATTAA

Protein sequence :
MVKNKLLAATLSISLVLPLITPYSEEAKAANTIEEIGEGAQIIKRTEDVSSRKWGVTQNIQFDFVKDPKYNKDALIIKMQ
GFIKSRTSFTDVKGKGYESTKRMLWPFQYNIALKTNDPNVSLINYLPKNKIESIDVSQTLGYNVGGNFQSAPLLGGKGAF
NYSKKISYTQKNYISEVAQQNSKNIRWEVKANSFNTENGQVSAYDRHLFVRSPIGPNARDFFVPNDELPPLIQSGFNPSF
IATVSHEKDKGDTSEFEIAYGRNLDITYATFFPRTGIFAERRHNALMNRNLVTKYEVNWKTHEIKVKGHN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukE YP_186708.1 leukotoxin LukE Virulence vSa¥â Protein 2e-113 74
lukE NP_646585.1 leukotoxin LukE Virulence vSa¥â Protein 2e-113 74
lukE NP_372344.1 leukotoxin S-subunit Virulence vSa¥â Protein 2e-113 74
lukE NP_374927.1 leukotoxin LukE Virulence vSa¥â Protein 2e-113 74
lukE YP_001332753.1 leukocidin LukE precursor Virulence vSa¥â Protein 2e-113 74
lukE YP_494460.1 leukotoxin LukE Virulence vSa¥â Protein 2e-113 74
SAKOR_01768 YP_008491956.1 Leukocidin S subunit lukE Virulence vSa¥â Protein 2e-113 74
SAOV_1909 YP_005737354.1 leukocidin chain lukM precursor Virulence ¥ÕSa3 Protein 2e-104 69
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor Virulence ¥ÕSa2 Protein 7e-95 66
lukS-PV YP_494079.1 Panton-Valentine leukocidin, LukS-PV Virulence ¥ÕSa2 Protein 7e-95 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lukS-I YP_006015105.1 synergohymenotropic toxin VFG1274 Protein 3e-90 68
lukS-I YP_006015105.1 synergohymenotropic toxin VFG1277 Protein 3e-95 66
lukS-I YP_006015105.1 synergohymenotropic toxin VFG1273 Protein 1e-103 66