Gene Information

Name : ureC (SPSE_0303)
Accession : YP_006014486.1
Strain : Staphylococcus pseudintermedius ED99
Genome accession: NC_017568
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 361340 - 363055 bp
Length : 1716 bp
Strand : +
Note : identified by match to protein family HMM PF00449, match to protein family HMM PF01979, match to protein family HMM TIGR01792

DNA sequence :
ATGAGTTTTAAAATGACAGAATCACAGTATACTAGTTTGTACGGCCCAACAGTCGGCGATTCTATTCGTTTAGCTGACAC
GGATTTATTTGCGAAAGTCGAAAAAGATTACGCAAGATATGGTGATGAGGTTACTTTCGGTGGTGGTAAATCAATCCGTG
ATGGTATGGGACAAAATCCGAATGCAACACGTGATAACAAAGCCGTGGCAGACCTAGTTATTTCAAATGCTGTCGTGATT
GATCACGATAAAGTCATTAAATGTGATATCGGTGTGAAAAATGGTTACATCATGAAATTAGGGAAAGCCGGCAACCCGGA
TATTATGGATGGTGTCGATATTATTATTGGTTCCTCGACAGATGTGATTGCAGCAGAGGGGATGATTGTTACTGCGGGCG
GTATTGATACACATGTACACTTTATTAACCCTGAACAAGCTGAAGTTGCATTAGAAAGTGGCATTACAACACATATCGGC
GGGGGAACTGGTGCTTCAGAAGGCTCAAAAGCAACAACGGTGACACCAGGTTCTTGGTATATTCACCGCATGCTTCAAGC
TGCAGAAAATTTGCCGCTTAACATTGGTTTTACAGGTAAAGGTCAAGCGGTGAACCCGACTGCATTAGTAGAACAAATTC
ATGCAGGGGTCATCGGTTTGAAAGTGCACGAAGATTGGGGTGCGACGCCTTCAGCATTACGTCATGCACTTGAAGTGGCA
GATGACTATGATATTCAAATCGCACTGCACGCGGATACTTTGAACGAAGCGGGCTTTATGGAAGATACGATGAAAGCGAT
TGGTGATAAAGTGATCCATATGTACCATACAGAAGGGGCTGGTGGTGGACACGCACCTGACTTAATTAAATCAGCGGGTT
ATCCGAATGTGCTACCATCATCGACGAACCCAACATTGCCGTATACACATAATACGATTGATGAACATCTAGACATGGTC
ATGATTACACACCATTTAAATGCATCGATTCCAGAAGACGTGGCTTTCGCGGATTCTCGTATTCGTAAAGAAACAATTGC
TGCAGAAGACGTTTTACAAGATATGGGTGTCTTTAGTATGATCAGCTCTGACTCTCAAGCGATGGGACGTGTCGGTGAAG
TCATTACGCGTGCATGGCAAGTCGCACATCGTATGAAACAACAACGCGGACCACTTGAAGGCGACAGTGAATATGATGAT
AATAACCGTATCCGTCGTTATATTGCGAAATATACGATTAACCCTGCCATTACACACGGCATATCCGAATATGTCGGTTC
TGTTGATGCCGGTAAATTAGCGGACCTTGTCATTTGGGATCCACGTTTCTTTGGTGTGAAACCGGACATGGTTGTTAAAG
GTGGCATGATTAACGTGGCGGCAAATGGTGATGCAAATGGTTCTATCCCAACATCTGAACCGATTAAGTATCGTCACATG
TACGGTCAATATGGTGGTAACTTACAAAGTACAGCCATCACTTTCGTATCACAAGCGGCTTATATGAACGGTATTCGTCG
TACATTAGACTTAAAACGTGACGTGAGACCTGTACGTAACATTCGCCAATTAACAAAAAAAGATATGAAAAATAATAGTG
CTTTACCAAAACTTGACGTTGATCCAGAAACATATGAAGTTTTCGTGGATGGGGAAAAAGTAACGAGTGAAGCGGCAACA
GAATTACCGATGACCCAACGTTATTTCTTATTCTAA

Protein sequence :
MSFKMTESQYTSLYGPTVGDSIRLADTDLFAKVEKDYARYGDEVTFGGGKSIRDGMGQNPNATRDNKAVADLVISNAVVI
DHDKVIKCDIGVKNGYIMKLGKAGNPDIMDGVDIIIGSSTDVIAAEGMIVTAGGIDTHVHFINPEQAEVALESGITTHIG
GGTGASEGSKATTVTPGSWYIHRMLQAAENLPLNIGFTGKGQAVNPTALVEQIHAGVIGLKVHEDWGATPSALRHALEVA
DDYDIQIALHADTLNEAGFMEDTMKAIGDKVIHMYHTEGAGGGHAPDLIKSAGYPNVLPSSTNPTLPYTHNTIDEHLDMV
MITHHLNASIPEDVAFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRAWQVAHRMKQQRGPLEGDSEYDD
NNRIRRYIAKYTINPAITHGISEYVGSVDAGKLADLVIWDPRFFGVKPDMVVKGGMINVAANGDANGSIPTSEPIKYRHM
YGQYGGNLQSTAITFVSQAAYMNGIRRTLDLKRDVRPVRNIRQLTKKDMKNNSALPKLDVDPETYEVFVDGEKVTSEAAT
ELPMTQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-174 63
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-172 63
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-174 63
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 6e-174 63
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 4e-171 62
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 4e-171 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_006014486.1 urease subunit alpha VFG0270 Protein 8e-157 58