Gene Information

Name : hlb (SPSE_2228)
Accession : YP_006016301.1
Strain : Staphylococcus pseudintermedius ED99
Genome accession: NC_017568
Putative virulence/resistance : Virulence
Product : beta-hemolysin
Function : -
COG functional category : -
COG ID : -
EC number : 3.1.4.12
Position : 2285305 - 2286297 bp
Length : 993 bp
Strand : +
Note : identified by match to protein family HMM PF03372, match to protein family HMM TIGR03395

DNA sequence :
ATGAAAAAATTAAAACAAAAAAAACGATTAACATCACTATTATTAGCCACTACAATGCTTTTAGGTATCATGAATACTGG
CGTTAGCCATGCTGCTTCAGACGAAAATCAAGCGGAATTAAAATTAGCGACGCACAATGTTTATATGCTTTCTGGTTTCC
TTTATCCTAACTGGGGGCAAAGTAAGCGTGCAGATTTAATTTCAAAATCTAAATATATACAAGATAATGATGTCGTAATT
TTCAATGAAGCATTCTATCCTGCTTCAGCAAATCAACTGTTCAATAATCTAAAATCTTCTTATCCTTATCAAACTGCGGT
ACTTGGCCGTTCCACTTCAGGATGGGACCGCACTGAAGGTCATTATTCAAGTACGACTTTTGAAAATGGTGGTGTTGCTA
TCGTAAGTAAATACCCTATTAGAGAGCGAATTCAACATATCTTCCAGCACGGATGCGGCTTTGATAATGATAGTAATAAA
GGCTTTGTCTATACTAAAATTGAAAAAAATGGAAAATTCGTTCACGTTATCGGTACACACACACAATCTGAGGATACACG
CTGCTCAGTAGGTCAAGATAGAGCAATTAGAGCTGAACAAATGAAAGAAATTAGCAATTTTGTAAAAAGTAAAAATATCC
CTAAAGATGAAGTAGTTTACATCGGTGGTGATATGAATGTAAATAAAAATGCTGGAAATGGTGAATTCCAAGACATGTTG
AAAAACTTAAATGTCAGCGATGTAACTTATACAGGTCATTCAAGCACATGGGATCCTCAATCTAACTCAATTGCCAAATA
CAATTATCCTAATAGTGCGCCAGAGTATTTAGACTATATTTTTGTAGATAAAGACCATCGCCAACCAGGCCAACTCATTA
ATGAAGCTGTAGCTGAAAAATCACCAACTTGGGATGTTTATAAATTCCCATACCTTTATGTCTACAATGACTACTCTGAT
CACTATCCAGTAAAAGCGTATAGTAAGTCATAG

Protein sequence :
MKKLKQKKRLTSLLLATTMLLGIMNTGVSHAASDENQAELKLATHNVYMLSGFLYPNWGQSKRADLISKSKYIQDNDVVI
FNEAFYPASANQLFNNLKSSYPYQTAVLGRSTSGWDRTEGHYSSTTFENGGVAIVSKYPIRERIQHIFQHGCGFDNDSNK
GFVYTKIEKNGKFVHVIGTHTQSEDTRCSVGQDRAIRAEQMKEISNFVKSKNIPKDEVVYIGGDMNVNKNAGNGEFQDML
KNLNVSDVTYTGHSSTWDPQSNSIAKYNYPNSAPEYLDYIFVDKDHRQPGQLINEAVAEKSPTWDVYKFPYLYVYNDYSD
HYPVKAYSKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlb NP_646757.1 truncated beta-hemplysin Not tested ¥ÕSa3 Protein 1e-100 77
truncated-hlb NP_372527.1 hypothetical protein Not tested ¥ÕSa3 Protein 4e-100 77
hlb NP_375112.1 hypothetical protein Not tested ¥ÕSa3 Protein 3e-100 77
unnamed CAA70683.2 sphingomyelinase-c Virulence LIPI-2 Protein 2e-71 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlb YP_006016301.1 beta-hemolysin VFG1798 Protein 2e-109 75
hlb YP_006016301.1 beta-hemolysin VFG0674 Protein 1e-71 54