Gene Information

Name : pyk (SPSE_1104)
Accession : YP_006015216.1
Strain : Staphylococcus pseudintermedius ED99
Genome accession: NC_017568
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 1134434 - 1136194 bp
Length : 1761 bp
Strand : +
Note : identified by match to protein family HMM PF00224, match to protein family HMM PF00391, match to protein family HMM PF02887, match to protein family HMM TIGR01064

DNA sequence :
ATGAAAAAAACTAAAATCGTTTGTACGATTGGACCAGCATCAGAATCAGAAGATATGTTAGAAAAGTTAATGAAAGCAGG
TATGAATGTTGCGCGATTAAACTTTTCACATGGCTCACATGATGAACATGCAGCACGTATTCGTTCAATTCGTAAAATAG
CGAAAAAGTTAGAGAAAAATATTGGTATCTTACTTGATACTAAAGGACCTGAAATCCGTACGCATGACATGAAAGATGGC
ATCATTACGCTTGAGAAAGGCTCACATGTCATCGTGAGCATGCAGGAAGTTGAAGGTACAGCGGAAAAGTTCTCTGTCAC
ATACGAAAACTTAATTAACGATGTTGAAGTCGGTTCATTTATTTTATTAGATGATGGCTTGATTGAATTAGAGGTAGAAT
CTATTGATCATGCAGCAGGTGAAGTTCACTGTAAAGTTTTAAATACGGGAGAACTTAAAAATAAAAAAGGTGTCAACTTA
CCAGGAGTACGTGTCAACTTACCAGGTATTACAGATAAAGATGCGGAAGATATTCGTTTTGGTATCGAACAAGACGTTGA
CTTTATTGCGGCAAGTTTCGTTCGTCGTGCAAGTGACGTTTTAGAAATCCGTAAAATTTTAGAAGAAGTGGGCAACCGTA
CAATTAGCATTATCCCTAAAATCGAAAATCAAGAAGGTATCGATAATATTGAAGAAATTCTTGAAGTTTCTGACGGCTTA
ATGGTAGCCAGAGGGGATATGGGTGTTGAAATTCCACCAGAAGCAGTGCCGATTGTACAAAAAGATTTAATCCGTAAATG
TAATAAGCTAGGGAAACCAGTTATTACTGCAACACAAATGTTAGACTCAATGCAACGTAATCCACGTGCGACACGTGCAG
AAGCGTCTGACGTAGCGAACGCGATTTACGATGGTACAGATGCGGTTATGCTTTCAGGTGAAACTGCAGCAGGGGCTTAT
CCAGAAGAAGCTGTTAAGGCAATGCATGATATCGCAGTAGCTGCTGAACAAGCTCAAAACTACAAGCAACTGTTATCAGA
CCGTACAAAACTTGTTGAAACTTCGCTCGTAAACGCAATTGGTGTATCTGCTGCACATACAGCCTTAAACTTAAGTGTTA
AAGCGATTGTGGCTGCAACAGAAAGTGGTAAAACTGCGCGTACGATTTCGAAGTATAGACCAAAATCTGACATTATCGCA
GTAACACCATTCGAAACAACAGCGCGTCAATGTACACTTGTATGGGGTGTATATCCAGTTGTTCGTGAAGGTAACTTTAC
TACAGATGAATTATTGAACAATTCTGTAGCAACAGCTATCGAAAGCGAACGTGTTGAAAACGGTGATTTACTCATTATCA
TAGCAGGTGTACCAACAGGTGAATCTGGTACGACAAACTTGATGAAGTTACATCTTGTCGGTGAAGACTTAGCAAGTGGT
CAAGGTATTGGTCGTAACTCAGCAGTAGGTCGTACAGTCGTTGTCAACAATGGTTCGGAATTAAAAGGTCGCGACTTAGA
CCAAGCTGTTATCGTGACACCATCAATTGACGAAAGCATTATCCCATATTTAGATCAGGCTGTAGCTTTAGTTACTGAAG
AAGCTGGCTTAACTTCTTCAAGTGCTATCATTGGACTTGAAAAAGGTATTCCAACAGTTGTAGGTGTCAACAATGTCGTT
GATACAATTCCTGATAACGCATTAGTTACAGTAGATGCGACGCAAGGTAGAGTTTATGAAGGTTATGCAAACGTATTATA
A

Protein sequence :
MKKTKIVCTIGPASESEDMLEKLMKAGMNVARLNFSHGSHDEHAARIRSIRKIAKKLEKNIGILLDTKGPEIRTHDMKDG
IITLEKGSHVIVSMQEVEGTAEKFSVTYENLINDVEVGSFILLDDGLIELEVESIDHAAGEVHCKVLNTGELKNKKGVNL
PGVRVNLPGITDKDAEDIRFGIEQDVDFIAASFVRRASDVLEIRKILEEVGNRTISIIPKIENQEGIDNIEEILEVSDGL
MVARGDMGVEIPPEAVPIVQKDLIRKCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGAY
PEEAVKAMHDIAVAAEQAQNYKQLLSDRTKLVETSLVNAIGVSAAHTALNLSVKAIVAATESGKTARTISKYRPKSDIIA
VTPFETTARQCTLVWGVYPVVREGNFTTDELLNNSVATAIESERVENGDLLIIIAGVPTGESGTTNLMKLHLVGEDLASG
QGIGRNSAVGRTVVVNNGSELKGRDLDQAVIVTPSIDESIIPYLDQAVALVTEEAGLTSSSAIIGLEKGIPTVVGVNNVV
DTIPDNALVTVDATQGRVYEGYANVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 9e-98 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-98 51
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-98 51
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-98 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_006015216.1 pyruvate kinase VFG0479 Protein 2e-98 51