Gene Information

Name : guaA (SDE12394_05335)
Accession : YP_006013127.1
Strain : Streptococcus dysgalactiae ATCC 12394
Genome accession: NC_017567
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1029897 - 1031459 bp
Length : 1563 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGACTGAAATTTCAATTTTGAATGATGTTCAAAAAATTATCGTTCTTGATTATGGTAGCCAGTACAACCAGCTGATTGC
TAGACGTATTCGAGAGTTCGGTGTTTTTTCCGAACTTAAAAGCCATAAAATCACCGCTCAAGAACTTCGTGAGATCAATC
CCATTGGTATCGTTTTATCAGGCGGACCTAACTCTGTCTACGCTGATAACGCCTTTGTTATTGACCCTGAAATCTTTGAA
CTAGGGATTCCGATTCTTGGTATCTGCTATGGAATGCAACTAATCACTCATATGTTAGGTGGTAAAGTTGTTCCTGCTGG
CCAAGCTGGAAATCGTGAGTACGGTCAGTCAACTCTTCACCTCCGTGCCGATTCAAAATTGTTTGCAGGTACTCCTGAAG
AGCAACTTGTTTTGATGAGTCATGGTGATGCTGTCACAGAAATTCCAGAAGGCTTCCATCTTGTTGGTGACTCAAACGAC
TGCCCTTATGCGGCTATGGAAAATACTGAGAAAAACCTTTACGGTATTCAGTTCCATCCAGAAGTGAGACACTCTGTGTA
TGGGAATGATATTCTAAAAAACTTTGCAGTCTCTATCTGTGGGGCGCGTGGCGACTGGTCAATGGATAATTTCATTGAAA
TGGAAATCGCGAAAATTCGTGAAACTGTAGGTAATCGTAAAGTTCTCCTCGGACTTTCTGGAGGAGTAGATTCTTCAGTT
GTTGGCGTCCTTCTTCAAAAAGCTATTGGTGATCAATTAACTTGTATCTTTGTAGATCATGGACTTCTTCGTAAGGATGA
AGGAGACCAAGTTATGGGAATGCTTGGGGGCAAATTCGGCCTAAATATTATCCGTGTGGATGCTTCAAAACGTTTCCTTG
ATCTTCTTGCAGACGTTGAAGATCCTGAGAAAAAACGTAAAATCATCGGTAATGAATTTGTTTACGTTTTTGATGACGAG
GCCAGTAAATTAAAAGGTGTTGATTTCCTTGCTCAAGGAACGCTCTACACTGATATTATCGAATCAGGAACAGAAACTGC
CCAAACCATTAAATCTCACCATAATGTGGGAGGCCTTCCTGAAGACATGCAATTTGAATTGATTGAACCTTTAAACACTC
TCTTTAAAGATGAAGTTCGTGCTCTTGGAATTGCTCTTGGAATGCCTGAAGAAATTGTTTGGCGTCAACCCTTCCCTGGA
CCTGGTTTAGCTATTCGTGTTATGGGAGCTATTACTGAAGAGAAACTTGAAACTGTCCGCGAGTCAGATGCTATCCTTCG
TGAAGAAATCGCTAAGGCCGGTTTAGATCGTGACGTGTGGCAATACTTTACAGTTAACACAGGTGTCCGTTCTGTAGGTG
TCATGGGAGATGGTCGTACTTATGATTATACCATTGCCATTCGTGCCATTACTTCAATTGACGGTATGACAGCTGACTTT
GCTCAACTCCCTTGGGAGGTCTTGAAAAAAATCTCAACGCGTATCGTCAACGAGGTTGATCATGTCAACCGTATCGTCTA
CGACATCACCAGCAAACCACCTGCAACCGTTGAGTGGGAATAA

Protein sequence :
MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITAQELREINPIGIVLSGGPNSVYADNAFVIDPEIFE
LGIPILGICYGMQLITHMLGGKVVPAGQAGNREYGQSTLHLRADSKLFAGTPEEQLVLMSHGDAVTEIPEGFHLVGDSND
CPYAAMENTEKNLYGIQFHPEVRHSVYGNDILKNFAVSICGARGDWSMDNFIEMEIAKIRETVGNRKVLLGLSGGVDSSV
VGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLGGKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDE
ASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEIVWRQPFPG
PGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADF
AQLPWEVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-175 69
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-176 69
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-175 69
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-119 52