Gene Information

Name : Y11_p0841 (Y11_p0841)
Accession : YP_006007932.1
Strain :
Genome accession: NC_017565
Putative virulence/resistance : Virulence
Product : type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 56778 - 58892 bp
Length : 2115 bp
Strand : +
Note : -

DNA sequence :
ATGAATCCCCATGATCTTGAGTGGCTAAATCGTATTGGCGAGCGTAAAGATATCATGCTGGCAGTGCTGCTGTTAGCTGT
GGTATTCATGATGGTCTTACCACTCCCCCCCCTCGTGTTGGACATTCTGATTGCTGTTAACATGACCATCTCAGTGGTGT
TGTTAATGATAGCGATCTATATCAACTCTCCTTTACAATTTTCAGCTTTCCCAGCGGTGCTACTCGTTACCACGTTATTT
CGTCTCGCACTTTCAGTTAGCACCACCCGCATGATCCTGCTACAAGCTGATGCGGGGCAGATTGTTTACACCTTTGGTAA
TTTCGTCGTTGGCGGTAACCTCATCGTCGGGATTGTCATCTTCCTGATCATCACTATTGTGCAATTTTTAGTGATAACGA
AAGGCTCAGAACGTGTAGCAGAAGTTAGTGCCAGATTCTCTCTTGATGCGATGCCGGGTAAACAGATGAGTATCGATGGC
GATATGCGAGCCGGGGTGATCGATGTCAATGAAGCGCGTGAGCGGCGCGCGACGATAGAAAAAGAAAGCCAAATGTTCGG
TTCTATGGACGGCGCCATGAAGTTCGTCAAAGGGGATGCAATAGCTGGCCTCATTATTATCTTTGTCAATATATTAGGCG
GCGTCACCATTGGTGTTACCCAAAAAGGATTAGCGGCCGCTGAGGCACTGCAACTCTATTCCATCCTCACTGTCGGGGAT
GGGATGGTTTCTCAGGTACCTGCCCTGCTGATAGCTATTACCGCGGGTATTATCGTCACCCGCGTCTCTTCAGAAGATTC
ATCAGACTTGGGTAGCGATATTGGCAAACAGGTTGTCGCTCAGCCTAAAGCCATGCTAATTGGTGGCGTACTGCTGTTGC
TCTTTGGTCTTATCCCCGGCTTCCCAACAGTCACCTTTCTGATTTTGGCGCTATTGGTAGGCTGTGGTGGTTATATGCTC
AGCCGTAAGCAGAGTCGTAATGACGAAGCTAATCAAGACCTGCAATCCATACTGACGAGCGGTTCTGGTGCCCCGGCTGC
CCGAACCAAAGCCAAAACAAGTGGGGCAAACAAGGGCCGACTAGGGGAACAAGAAGCATTTGCTATGACGGTTCCCTTGC
TGATTGATGTAGATTCAAGCCAACAGGAAGCACTGGAAGCAATAGCACTAAATGATGAGCTGGTTCGAGTGCGCCGTGCT
CTTTATCTTGATCTTGGCGTACCTTTCCCTGGGATCCATCTGCGTTTTAATGAGGGGATGGGTGAAGGCGAATATCTTAT
TTCCTTGCAAGAAGTTCCTGTGGCGCGAGGTGAGCTTAAGGCAGGTTATTTACTCGTGCGTGAATCCGTCAGCCAACTCG
AATTACTGGGTATACCCTATGAAAAAGGGGAACATTTGCTACCCGATCAGGAAACTTTCTGGGTATCGGTTGAATATGAG
GAGCGCCTGGAAAAGTCTCAACTGGAATTTTTCTCTCATTCCCAAGTTCTAACCTGGCATCTTTCTCATGTCCTACGTGA
ATATGCCGAAGATTTCATTGGTATCCAAGAAACCCGCTATCTGCTCGAACAGATGGAAGGAGGCTATGGCGAATTAATTA
AAGAAGTACAAAGAATCGTTCCCTTACAACGAATGACCGAAATATTACAACGATTAGTTGGAGAAGATATTTCTATCCGT
AATATGCGGTCTATTCTTGAAGCTATGGTGGAATGGGGACAAAAGGAGAAAGACGTCGTTCAACTCACAGAATATATCCG
CAGTAGTCTAAAACGTTATATCTGCTACAAATACGCTAATGGCAACAATATATTGCCAGCTTATCTTTTCGATCAAGAAG
TAGAAGAAAAAATTCGTAGCGGTGTGCGCCAAACCAGTGCAGGGAGTTATTTGGCATTGGATCCTGCTGTTACCGAGAGT
TTACTTGAACAAGTCCGCAAGACTATTGGCGATCTGTCGCAAATCCAGAGTAAACCGGTGCTGATTGTTTCTATGGATAT
TCGTCGCTATGTGCGCAAACTGATTGAGAGCGAATACTATGGCTTGCCGGTACTTTCATACCAAGAGCTGACTCAGCAGA
TTAATATCCAACCACTTGGACGAGTTTGCTTATGA

Protein sequence :
MNPHDLEWLNRIGERKDIMLAVLLLAVVFMMVLPLPPLVLDILIAVNMTISVVLLMIAIYINSPLQFSAFPAVLLVTTLF
RLALSVSTTRMILLQADAGQIVYTFGNFVVGGNLIVGIVIFLIITIVQFLVITKGSERVAEVSARFSLDAMPGKQMSIDG
DMRAGVIDVNEARERRATIEKESQMFGSMDGAMKFVKGDAIAGLIIIFVNILGGVTIGVTQKGLAAAEALQLYSILTVGD
GMVSQVPALLIAITAGIIVTRVSSEDSSDLGSDIGKQVVAQPKAMLIGGVLLLLFGLIPGFPTVTFLILALLVGCGGYML
SRKQSRNDEANQDLQSILTSGSGAPAARTKAKTSGANKGRLGEQEAFAMTVPLLIDVDSSQQEALEAIALNDELVRVRRA
LYLDLGVPFPGIHLRFNEGMGEGEYLISLQEVPVARGELKAGYLLVRESVSQLELLGIPYEKGEHLLPDQETFWVSVEYE
ERLEKSQLEFFSHSQVLTWHLSHVLREYAEDFIGIQETRYLLEQMEGGYGELIKEVQRIVPLQRMTEILQRLVGEDISIR
NMRSILEAMVEWGQKEKDVVQLTEYIRSSLKRYICYKYANGNNILPAYLFDQEVEEKIRSGVRQTSAGSYLALDPAVTES
LLEQVRKTIGDLSQIQSKPVLIVSMDIRRYVRKLIESEYYGLPVLSYQELTQQINIQPLGRVCL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lssD AAO18050.1 LssD Virulence TTSS locus Protein 0.0 83
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 6e-104 44
hrcV AAT96337.1 HrcV Virulence S-PAI Protein 1e-100 44
hrcV AAT96297.1 HrcV Virulence S-PAI Protein 3e-100 44
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 6e-100 43
escV AFO66414.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 5e-100 43
unnamed AAL06368.1 EscV Virulence LEE Protein 3e-98 43
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 7e-105 43
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 7e-105 43
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 7e-105 43
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 7e-105 43
hrcV AAT96256.1 HrcV Virulence S-PAI Protein 8e-100 43
escV CAC81861.1 EscV protein Virulence LEE II Protein 2e-99 42
escV AAK26714.1 EscV Virulence LEE Protein 1e-99 42
escV AAL57541.1 EscV Virulence LEE Protein 1e-99 42
escV CAI43875.1 EscV protein Virulence LEE Protein 1e-99 42
escV NP_290269.1 hypothetical protein Virulence LEE Protein 1e-98 42
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 1e-98 42
escV AAC31514.1 L0035 Virulence LEE Protein 1e-98 42
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 1e-98 42
escV ACU09459.1 EscV protein Virulence LEE Protein 1e-98 42
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 2e-99 42
escV AAC38382.1 EscV Virulence LEE Protein 3e-99 42
escV YP_003223476.1 translocator EscV Virulence LEE Protein 1e-99 42
ECs3731 NP_311758.1 EivA Not tested LIM Protein 4e-103 42
hrcV ABA47273.1 HrcV Virulence S-PAI Protein 3e-97 42
XC_3013 YP_244081.1 HrcV protein Virulence Hrp PAI Protein 7e-80 41
hrcV NP_636603.1 protein HrcV Virulence Hrp PAI Protein 7e-80 41
invA AAS66860.1 InvA Not tested SSR-2 Protein 2e-96 41
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 2e-96 41
hrcV AAR25631.1 type III secretion protein HrcV Not tested Not named Protein 4e-93 41
hrcV AAT96193.1 HrcV Virulence T-PAI Protein 5e-95 41
hrcV AAT96139.1 HrcV Virulence T-PAI Protein 7e-95 41
hrcV AAB05999.2 HrcV Virulence Hrp PAI Protein 2e-100 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Y11_p0841 YP_006007932.1 type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV) VFG0384 Protein 0.0 99
Y11_p0841 YP_006007932.1 type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV) VFG0198 Protein 0.0 80
Y11_p0841 YP_006007932.1 type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV) VFG0064 Protein 3e-178 59
Y11_p0841 YP_006007932.1 type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV) VFG2126 Protein 2e-129 46
Y11_p0841 YP_006007932.1 type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV) VFG0557 Protein 3e-105 43
Y11_p0841 YP_006007932.1 type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV) VFG0729 Protein 2e-99 42
Y11_p0841 YP_006007932.1 type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV) VFG0813 Protein 6e-99 42
Y11_p0841 YP_006007932.1 type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV) VFG2461 Protein 2e-97 42
Y11_p0841 YP_006007932.1 type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV) VFG1006 Protein 5e-98 41
Y11_p0841 YP_006007932.1 type III secretion inner membrane channel protein (LcrD,HrcV,EscV,SsaV) VFG1780 Protein 2e-94 41