Gene Information

Name : Y11_37701 (Y11_37701)
Accession : YP_006007269.1
Strain : Yersinia enterocolitica Y11
Genome accession: NC_017564
Putative virulence/resistance : Resistance
Product : cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3911188 - 3914274 bp
Length : 3087 bp
Strand : +
Note : -

DNA sequence :
ATGAAGCTGCTTGATAATTATATCAATAATAGTACCCGTATCTGGTTAACGATTCTGTTGCTGGGTGTTGGGGGTATTAT
TGCCTATCTCAATATAGGCAGGCTGGAAGACCCGGCCTTTACCATCAAAACGGCAGTAGTTGTCACCCGCTATGATGGCG
CGTCGGCACAACAGGTTGAAGAAGAAGTCACGTTGCCGCTGGAGAATGCCATTCAGGAACTCTCTTATGTCGATGATGTT
ACCTCCATTTCCAGTGCGGGCTTATCGCAAATTACCATCAATATTCGTGCGCAATATGGGGCGAATGAATTACCGCAAAT
CTGGGATGAATTGCGGCGTAAGATAAATGATAACAGTGTGCGGTTGCCACCGGGTGCCAGTGCGCCGATGGTCAACGACG
ACTTCGGCGATGTGTATGGTTTCTTCTTCTCACTCACCGGTGATGGCTACAGTAATCAGGATTTACGCAACTTTGCCGAG
CAATTACGGCGTGAGTTGGTACTGGTGCCGGGGGTCGGTAAAGTGGGGATTGTCGGTATCTTGCCTGAAGAAGTTCAGGT
AGAGATTTCTCGTGCCCAGATGACCGCCGCAGGTATTACGCCACAACAATTATCCGACTTACTTGCTCGTCAGAATGTGG
TGTCCGATGCCGGCCAACTACAGGTGGGTAGTGAGTCGATTCGTTTGCATCCAACCGGTGAATTCCAGAGTGTACAAGAG
CTGGGGAACTTATTGGTTAGTCAGCCCGGCAGCCCGAAAAGTGTCTATTTACGCGATATCGCGACCGTGACACAAGGTTT
TGGTCATTCACCGACAAATATTTATCGTGCTAATGGTAAGCCTGCGTTAGCGCTAGGGATCTCATTCGCCCCGAATGTCA
ATGTAGTGAATGTGGGTAATGCCATTAAAGCTCGGCTGGCGCAGTTGGAAGGCGAGCGCCCGTCAGGCATGCATATCAAT
GTGTTTTATGACCAGTCCCATGAAGTTGAGGGGGCGGTCAACGGCTTTATCCTTAACTTCCTGCTGGCACTGCTCATTGT
TGTTGTCACGCTACTTATCTTTATGGGGGTACGCAGCGGTGTGGTGATTGCCATCTCGCTGGCACTGAACGTACTTGGCA
CCTTGCTCATTATGTGGCTGTTTAATATCGAGCTACAGCGAGTGTCGCTAGGGGCGCTAATTATCGCGCTAAGTATGTTG
GTGGATAACGCCATTGTAGTGGTGGAGGGGATTGTGGTGGGCCGCCAGCGCGGCGAAAGTCTCTCTACGGCGATCGGCAA
TGTGGTGAAGCGCTCGATGATGCCGCTGCTAGGCGCGACAGTGATTGCCATTTTGGCCTTTGCCCCGATTGGCCTGTCCA
ACGATGCAACCGGTGAATATTGTAAATCGCTATTCCAAGTGTTGTTAATCTCGTTGATGTTGAGCTGGATTACCGCGCTG
ACATTGACACCGGTGTTTTCTAAGTGGGCATTCCAGAATCAAAAACCGGCGAAGGTGGATGAGGATAAACCGGCTAAGCA
ACCTTATGATGGCTGGCTGTTCCGCTATTATCGTGTGGTGCTGAATAAATTACTGCAATACCGTGCAGTCACTTTGGTGC
TGCTGGCGGCCATGTTAGTGGCGTCGGTGGTGGGCTTTGGCAATGTTCGCCAGAGCTTCTTCCCACCGTCAAACACGCCC
ATTTTCTTTGTTGATATTTGGCTGCCGAATGGCACTGATATCAGTTATACCGAAGGGGTGGCGAGTAAGGTCGAGCAATA
TATCAAACAGCAAAAAGGGGTGGCTGACACTATGGCGACCATAGGTCAGGGCGCGATGCGCTTTATGCTGACTTATAACG
CCCAGCGTCATTATCCTAACTATGCGCAGGTGATGGTTCGAACCGAGCAGCTAGACCAAATCCCAGGTTTGATTGATGAA
ATTGAAGCCTACATGCATGACGAATACCCGCAAGTTGATGCGCAGATAAAACGTATTATGTTCGGGCCGTCAAACAACAG
CTCGATTGAAGCCCGCTTTATTGGCCCTGATCCCGAGGTATTACGCAGTTTGGCCGCACAGGCGGAAAAAGCGATTATTG
CTGATCCGATGGCCGATGGCGCACGGCATGACTGGCAAGATCGCAGCAAAATGATTCGGCCACAATTCTCTGATTATCTC
GGCCGCGAGCTGGGGGTGGATAAACGTGAGGTTGACGGCACCTTGCGCATGAGTTTTGGTGGCTTGCCGGTTGGCTTATA
CCGCGATGGCACCCGCCTGATGCCGATTGTGTTGCGCACGCCAGATTCCGAGCGGCTCAATGCTGAACGACTCAATGATG
TGATGGTGTGGAGTCAGGCACGCCAGGCCTTTATCCCTATCGATAACGTCGTGACCAGTTTTGAGACCGAGTGGGAAGAT
CCACTTATCATGCGGCTGGATCGCAAACGGACATTGACGGTGCAAACTGATCCAACTCAGCAAGGGGGCGAAACCTCGGC
TGAGTTATTACAGCGCATCAAGCCAGGGGTTGAGTCTATTCAATTGCCGCGCGGCTATGAACTTGAATGGGGCGGTGACT
ACGAAAGTACCAAAGAAGCACAACGGGGTATTTTCATCAGTTTGCCGATAGCATTCCTGATTATGTTTGTGGTGACCGTC
TTGATGTTTAGCTCGGTGCGTAACGCGCTCGCTATCTGGCTGACGGTGCCATTAGCACTGATTGGTGTGACTGTGGGCTT
CTTGCTCACCGGTATTCCATTTGGTTTTATGGCCTTACTGGGGCTATTGAGTCTGAGTGGGATGTTGATACGTAATGGCA
TTGTGCTGGTGGAAGAAATTGGCCTCCAGCGGCAGGAAAAACCACTGCGTGATGCCATTATTGATGCTTCCACTGCGCGT
TTACGCCCTATCATGTTAACTGCATTTACCACGGTTTTGGGGCTAGCCCCGCTGCTCAGCGATGCTTTCTTCCAGAGTAT
GGCGGTGGTGATTATGTTTGGTCTGGGCTTTGCAACTGTACTGACCCTACTGGTGTTGCCAGTGATATATAGCTGTATGA
ATCCGGAACCAAAAGAGAAGGCGCATGATGAGCCAGTTAGTGAATAA

Protein sequence :
MKLLDNYINNSTRIWLTILLLGVGGIIAYLNIGRLEDPAFTIKTAVVVTRYDGASAQQVEEEVTLPLENAIQELSYVDDV
TSISSAGLSQITINIRAQYGANELPQIWDELRRKINDNSVRLPPGASAPMVNDDFGDVYGFFFSLTGDGYSNQDLRNFAE
QLRRELVLVPGVGKVGIVGILPEEVQVEISRAQMTAAGITPQQLSDLLARQNVVSDAGQLQVGSESIRLHPTGEFQSVQE
LGNLLVSQPGSPKSVYLRDIATVTQGFGHSPTNIYRANGKPALALGISFAPNVNVVNVGNAIKARLAQLEGERPSGMHIN
VFYDQSHEVEGAVNGFILNFLLALLIVVVTLLIFMGVRSGVVIAISLALNVLGTLLIMWLFNIELQRVSLGALIIALSML
VDNAIVVVEGIVVGRQRGESLSTAIGNVVKRSMMPLLGATVIAILAFAPIGLSNDATGEYCKSLFQVLLISLMLSWITAL
TLTPVFSKWAFQNQKPAKVDEDKPAKQPYDGWLFRYYRVVLNKLLQYRAVTLVLLAAMLVASVVGFGNVRQSFFPPSNTP
IFFVDIWLPNGTDISYTEGVASKVEQYIKQQKGVADTMATIGQGAMRFMLTYNAQRHYPNYAQVMVRTEQLDQIPGLIDE
IEAYMHDEYPQVDAQIKRIMFGPSNNSSIEARFIGPDPEVLRSLAAQAEKAIIADPMADGARHDWQDRSKMIRPQFSDYL
GRELGVDKREVDGTLRMSFGGLPVGLYRDGTRLMPIVLRTPDSERLNAERLNDVMVWSQARQAFIPIDNVVTSFETEWED
PLIMRLDRKRTLTVQTDPTQQGGETSAELLQRIKPGVESIQLPRGYELEWGGDYESTKEAQRGIFISLPIAFLIMFVVTV
LMFSSVRNALAIWLTVPLALIGVTVGFLLTGIPFGFMALLGLLSLSGMLIRNGIVLVEEIGLQRQEKPLRDAIIDASTAR
LRPIMLTAFTTVLGLAPLLSDAFFQSMAVVIMFGLGFATVLTLLVLPVIYSCMNPEPKEKAHDEPVSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 1e-171 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Y11_37701 YP_006007269.1 cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA BAC0428 Protein 0.0 51
Y11_37701 YP_006007269.1 cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA BAC0519 Protein 0.0 50
Y11_37701 YP_006007269.1 cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA BAC0526 Protein 0.0 48
Y11_37701 YP_006007269.1 cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA BAC0425 Protein 7e-172 41