Gene Information

Name : TIIST44_02880 (TIIST44_02880)
Accession : YP_005985105.1
Strain : Propionibacterium acnes ATCC 11828
Genome accession: NC_017550
Putative virulence/resistance : Virulence
Product : ATP-dependent protease (Clp chaperone)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 627661 - 630234 bp
Length : 2574 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGGACACCAATCTCACCACGATGAGCCGTGACGCGGTCACCGCCGCTACTCGACATGCGTTGGCCCACGGGAACCCGTC
CGTGGAGCCCTCGCATCTTCTTCACGCACTGTTCACGATCCCAGACAACACTGTCAGTCCGTTGGTAGCTGGCTTGGGGA
TCGATCCTCAGCAGGTCGACGCCGTCGCCACCGCGGCGATGCGCTCCCTTCCGTCAATCACCGGCGCCTCGGTGGCTCAG
CCGCAGCTGTCCGGGGCGTTCGCCCGTGTCATCGCCGACGCACAGAACCGCGCCGAGGCCATGGGTGACTCTTTCGTCGC
TACCGAGCACCTGCTTATTTCATTGACGGCTGTCCCCTCTGACGTCCAGAACGGCCTGGCAGGACTCGGCCTCAAGCCCG
ACTCCCTGGCGGCGGCCTTTAATGAAGGTCGCGGAGACCGTCGTGTCACCTCCGAGGAGTCGGAGGGAGGCGAATCGGCT
CTTGCCAAGTACTCTGTCGACCTCACCGAGCGCGCCCGTGCTGGCAAGCTTGACCCCGTCATTGGTCGTGATCAGGAGAT
TCGCCGCGTCGTCCAGGTGTTGGCACGACGCACTAAGAACAACCCGGTCCTTATCGGTGAGCCGGGGGTCGGCAAGACTG
CCGTCGTCGAAGGGTTGGCTCAGCGCGTCGTCGCCGGGGACGTTCCCGACTCTCTCAAAGGGCGTCGCGTCGTCTCTTTG
GATCTGTCTTCCATGGTCGCCGGGGCTAAATACCGCGGCGAGTTTGAGGAGCGCCTCAAGGCCGTCCTCAACGAGATCAA
GGAGGCCGAGGGGCAGATCATTACCTTCATCGACGAGCTGCACACCGTCGTCGGCGCCGGGGCTTCCGGAGAGGGAGCAA
TGGACGCTGGCAATATGCTCAAGCCGATGCTGGCCCGTGGCGAGCTGCGAATGATCGGTGCCACTACCCTCGACGAGTAC
CGCGAGCATATTGAGAAGGACCCAGCCCTGGAGCGTCGTTTCCAGCAGGTCTTTGTCGGTGAACCGTCGGTTGAGGACAC
TATTGCCATCCTGCGCGGCTTGCGAGAGCGCTACGAGGCCCACCACAAGGTGCGTATTACTGACGGAGCCCTTGTCGCGG
CCGCCAGCTTGTCTAACCGGTACATCACCGCCCGTCAGCTTCCTGACAAGGCCATTGACCTTATCGACGAGGCTGCGTCT
CGGCTGCGCATGGAGATTGACTCCTCTCCGGAGGAGATCGACACCCTGCGCCGTGAAGTCGACCGCATGAAGATGGAGAT
CTTCGCCGTCGAGAAGGAGGACGACCCGGCCAGCCAGCAGCGCCTAGCGAGGTTGCGCGCTGAAATGGCTGACAAGGAGG
AGACCCTGCGTGGCCTGGAGTCGCGCTGGGAGGCTGAGAAGGCTGGTCTCAACAAGGTCGGTGAGCTCAAGACAAGGATT
GACGAGTTGCGGACTGCCGCCGACAAGTACCAGCGCGAGGGCGACTTCGGGCGAGCGTCCGAAATCCTCTACGGTCAGAT
TCCCGGCCTTGAGAAGGAGATGGAGGCTGCTGCCAAGGCCGAGGAGGAAACCCCGCGGATGGTCTCCGAGGAGGTCGGCA
CCTCCGACATCGCCGAGGTTGTTTCCTCGTGGACTGGCATTCCCGTTGGGCGGATGATGCAGGGCGAGCAGGAGAAGCTG
CTCCATATGGAGGAGCGGCTGCACGAACGTCTTATTGGTCAGGATCGAGCGGTCAAGACGGTTTCGGATGCGGTACGTCG
CTCCCGGGCGGGAATCAGCGACCCGAACCGTCCGACTGGCTCGTTTCTCTTTTTGGGCCCCACGGGCGTCGGCAAGACCG
AGTTGGCCAAGTCTCTGGCGGAGTTCCTCTTCGACGACGAGACCGCTCTGGTGCGTATCGACATGAGTGAGTACATGGAG
AAGCACTCCGTCTCGCGTCTGGTCGGTGCCCCTCCGGGTTACGTCGGTTATGAAGAGGGCGGTCAGCTCACCGAAGCCGT
GCGGCGTCGTCCCTACTCGGTCATCTTGCTTGACGAGGTGGAAAAGGCTCATCCTGACGTCTTCAACATTTTGCTGCAGG
TGCTCGACGACGGTCGTCTGACTGACGGCCAAGGACGCACGGTGGATTTCCGCAACACCATTTTGGTCTTGACGAGCAAT
TTGGGTAGCCAGTTCCTGTCAGACGCGAGCCTTGATGACCATGCTAAGCGTGAGGCCGTCATGGGGGCGGTGCGTCAGGC
GTTCCGACCCGAGTTCCTGAATCGACTCGACGATGTGGTCATGTTCGACCCGTTATCGATGGCCGATCTGGGACGAATCG
TCGAGACGAACCTGGCTAAGCTCAATTCACGGCTGGCAGAGCGGCGTATCACCATTGCCGTGACCGACGCCGGTAAGGAC
TGGCTGGCCATGGCGGGTTTCGACCCGATCTACGGTGCCCGGCCACTGCGTCGCCTGATGCAGACCACCATCGATGATCA
GCTGGCTCGCAAGGTGTTGTCTGGGCAAGTGCAGGAGGGCGATACGGCGACCTTTGACATCAACGAGGCTGGTGACGGTT
TGGTGATTCTCTGA

Protein sequence :
MDTNLTTMSRDAVTAATRHALAHGNPSVEPSHLLHALFTIPDNTVSPLVAGLGIDPQQVDAVATAAMRSLPSITGASVAQ
PQLSGAFARVIADAQNRAEAMGDSFVATEHLLISLTAVPSDVQNGLAGLGLKPDSLAAAFNEGRGDRRVTSEESEGGESA
LAKYSVDLTERARAGKLDPVIGRDQEIRRVVQVLARRTKNNPVLIGEPGVGKTAVVEGLAQRVVAGDVPDSLKGRRVVSL
DLSSMVAGAKYRGEFEERLKAVLNEIKEAEGQIITFIDELHTVVGAGASGEGAMDAGNMLKPMLARGELRMIGATTLDEY
REHIEKDPALERRFQQVFVGEPSVEDTIAILRGLRERYEAHHKVRITDGALVAAASLSNRYITARQLPDKAIDLIDEAAS
RLRMEIDSSPEEIDTLRREVDRMKMEIFAVEKEDDPASQQRLARLRAEMADKEETLRGLESRWEAEKAGLNKVGELKTRI
DELRTAADKYQREGDFGRASEILYGQIPGLEKEMEAAAKAEEETPRMVSEEVGTSDIAEVVSSWTGIPVGRMMQGEQEKL
LHMEERLHERLIGQDRAVKTVSDAVRRSRAGISDPNRPTGSFLFLGPTGVGKTELAKSLAEFLFDDETALVRIDMSEYME
KHSVSRLVGAPPGYVGYEEGGQLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTILVLTSN
LGSQFLSDASLDDHAKREAVMGAVRQAFRPEFLNRLDDVVMFDPLSMADLGRIVETNLAKLNSRLAERRITIAVTDAGKD
WLAMAGFDPIYGARPLRRLMQTTIDDQLARKVLSGQVQEGDTATFDINEAGDGLVIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 7e-108 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TIIST44_02880 YP_005985105.1 ATP-dependent protease (Clp chaperone) VFG2084 Protein 1e-112 43