Gene Information

Name : TIIST44_06085 (TIIST44_06085)
Accession : YP_005985715.1
Strain : Propionibacterium acnes ATCC 11828
Genome accession: NC_017550
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1319296 - 1321830 bp
Length : 2535 bp
Strand : +
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGTTCGAACGGTTCACCGATCGGGCCCGCCGGGTCGTCGTCCTGGCCCAGGATGAGGCCAAGGCCCTGAACCACAATTA
CATTGGCACTGAGCACCTGCTGCTCGGGCTCATTAGCGAGGGCGAGGGAGTCGCTGCTAAGGCTCTCGAGTCCCTTGACA
TTTCACTGGAGGCTGTCCGCGCCCAGGTGGAGGAGATTATTGGCCACGGCACCTCAACGCCGACGGGCCACATTCCCTTT
ACCCCGCGTGCCAAGAAGGTTCTTGAACTGAGCCTGCGTGAAGCCCTCCAGATGAATCATTCGTACATTGGCACCGAGCA
CATTCTGCTTGGCCTTATCCGGGAGGGAGAAGGCGTCGCTGCTCAGGTACTGATCCGGCTGGGTGCTGACCTCAATACGG
TGCGCAATAGCGTCTTGCAACTGTTGCAGGGATATCAGGGCGACGAGCGTCAGGCCGCCACTTCCGGCGCCCCCGAGGCC
GGACCGCAGCAGTCCTCGGCGACGATTCTTGACCAATTCGGTCGCAACCTTACCGAGGCCGCCCGCGACGGCGAGCTCGA
CCCGGTCATCGGGCGTGAGAGGGAAATCGAGCGGGTTATGGTGGTGCTGAGCCGGCGCACCAAGAATAACCCGGTTCTTA
TTGGTGAGCCCGGCGTCGGTAAGTCTGCTTGTGTCGAGGGCCTGGCTCAGGCCATTGTGCGTGGAGACGTTCCCGAGACT
CTGCGCGACAAGAAGATCTACTCTCTGGACCTTGGCTCCATGGTTGCGGGATCGCGTTACCGCGGCGATTTCGAGGAGAG
AATGAAGAAGGTCCTCAAGGAGATTAAAAACCGCGGGGACATCATCCTGTTCATTGACGAGATCCACACCCTTGTTGGCG
CCGGTGCCGCCGAAGGGGCAATCGACGCTGCCAGCATGCTCAAGCCGATGCTGGCTCGCGGCGAGCTGCAGACTATCGGT
GCGACAACCCTCGACGAGTACCGTAAGTACATCGAGAAGGACGCCGCCCTGGAGCGTCGCTTCCAGCCGATCCAGGTAGA
CGAGCCCTCGATCCCCCTGGCCATCGAGATCCTTAAGGGTCTGCGCGACCGATACGAGGCCCACCACAAGATCACCATCA
CCGACGAGGCGATCACCTCCGCGGCGAATCTTGCGTCCCGTTACATCCAAGACCGCTTCCTGCCGGACAAGGCCATCGAT
CTCATTGACGAGGCCGGTGCCCGGATGAACATCCGCCGTATGACGGCTCCGCCGGATCTGCGCGAGTTCGACGAGCGGAT
CGCTCGTGTGCGAGTGGAGAAAGAGGCTGCCATCGACGCCCAGGATTTTGAGCGTGCTGCTGGGTTGCGCGACGACGAGA
AGAAACTTCTCGCTGAACGTGAGGCCAAGGAGGAGGAGTGGAAGCAGGGTGACGAGTCGGTGCCAGCCGTGGTCGGCCCC
GACGAGATCGCCGAGGTGCTCTCTGGAGCTACCGGCATTCCGGTCTTCAAGCTCACGGAGGAGGAATCCCAGCGTCTGCT
CCACATGGAGGATGAGATCGGCAAGCGCTACGTCGGCCAGGAGGACGCCGTCAAGGCCCTGTGCCGCTCTATCCGACGCA
CCCGCGCCGGCCTCAAGGATCCGAAGCGTCCGGCAGGTTCGTTCATTTTTGCTGGCCCGTCGGGTGTTGGTAAGACCGAG
CTCACCAAGGCGCTCACCGAGTTCCTCTTCGGTGACGAGGACGCCCTCATCACCCTCGACATGAGCGAGTACTCCGAGAA
ACACACCGCCTCGCGGATGTTTGGGTCCCCGCCTGGATTCGTCGGGTACGAGGAGGGCGGCCAGCTCACCGAGAAGGTGC
GCCGCAAGCCGTTCAGCGTCATTCTCTTTGACGAGATCGAAAAGGCCCACCCCGATATCTTCAATTCTCTGTTGCAGATT
CTTGACGAGGGACGTCTTACTGACGCCCAGGGCCGTGTAGTGGACTTTAAGAACACCGTCATTGTGCTGACGACCAACCT
CGGCACCCGCGACATTTCCAAATCAGTCAATCTCGGCTTCTCCAAGGCCGACGACGTCGAGTCCAGCTACGAGAAGATGA
AGGCCAAGGTTACCGAGGAGCTCAAGGGACACTTCCGTCCCGAGTTCCTCAACCGCCTTGACGAGATCATCGTCTTCCAT
CAGCTCACCCAGCCCGACATCCTACGGATTGTCGACCTCATGGTGGGGCAACTGGAAGATCGCCTGGCCGACAAGGATAT
GGGTATCGAGGTCACTCCGGCTGCCAAGGAACTGCTGTCCAAGCGTGGTTTCGACCCGCTGCTTGGTGCTCGTCCGCTGC
GCCGGACGATCCAGCGCGACATCGAGGACGTCCTAGCCGAGAAGATCCTCTTCGGGGAAGTCAAACCTGGTCAGATCGTG
GTGGTCGATGCTGCCCCGGAGGGTTCCGAGGAGCCGTTCGTCTTCACCGGCACGGAGCGCTCAGAGCTGCCTGACGAGGT
TCCTCCTGAGCTCACCTCTTCGGCAGGGGAAAATAACAAGGGGCAGCAGGGTTGA

Protein sequence :
MFERFTDRARRVVVLAQDEAKALNHNYIGTEHLLLGLISEGEGVAAKALESLDISLEAVRAQVEEIIGHGTSTPTGHIPF
TPRAKKVLELSLREALQMNHSYIGTEHILLGLIREGEGVAAQVLIRLGADLNTVRNSVLQLLQGYQGDERQAATSGAPEA
GPQQSSATILDQFGRNLTEAARDGELDPVIGREREIERVMVVLSRRTKNNPVLIGEPGVGKSACVEGLAQAIVRGDVPET
LRDKKIYSLDLGSMVAGSRYRGDFEERMKKVLKEIKNRGDIILFIDEIHTLVGAGAAEGAIDAASMLKPMLARGELQTIG
ATTLDEYRKYIEKDAALERRFQPIQVDEPSIPLAIEILKGLRDRYEAHHKITITDEAITSAANLASRYIQDRFLPDKAID
LIDEAGARMNIRRMTAPPDLREFDERIARVRVEKEAAIDAQDFERAAGLRDDEKKLLAEREAKEEEWKQGDESVPAVVGP
DEIAEVLSGATGIPVFKLTEEESQRLLHMEDEIGKRYVGQEDAVKALCRSIRRTRAGLKDPKRPAGSFIFAGPSGVGKTE
LTKALTEFLFGDEDALITLDMSEYSEKHTASRMFGSPPGFVGYEEGGQLTEKVRRKPFSVILFDEIEKAHPDIFNSLLQI
LDEGRLTDAQGRVVDFKNTVIVLTTNLGTRDISKSVNLGFSKADDVESSYEKMKAKVTEELKGHFRPEFLNRLDEIIVFH
QLTQPDILRIVDLMVGQLEDRLADKDMGIEVTPAAKELLSKRGFDPLLGARPLRRTIQRDIEDVLAEKILFGEVKPGQIV
VVDAAPEGSEEPFVFTGTERSELPDEVPPELTSSAGENNKGQQG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 71

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TIIST44_06085 YP_005985715.1 negative regulator of genetic competence ClpC/MecB VFG0079 Protein 0.0 58
TIIST44_06085 YP_005985715.1 negative regulator of genetic competence ClpC/MecB VFG0080 Protein 4e-152 51