Gene Information

Name : hpcC (NCGM2_5324)
Accession : YP_005983530.1
Strain : Pseudomonas aeruginosa NCGM2.S1
Genome accession: NC_017549
Putative virulence/resistance : Virulence
Product : 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5705800 - 5707260 bp
Length : 1461 bp
Strand : +
Note : similar to GI:116052157; similar to PA14_10630 of P. aeruginosa UCBPP-PA14

DNA sequence :
ATGATCAAACACTGGATCAATGGCCGCGAGGTCGAAAGCAAGGACGTCTTCGAGAACTACAACCCGGCCACCGGCGAGCT
GATCGGCGAGGTCGCCAGCGGCGGCGCGGCGGAAATCGACGCGGCGGTGGCGGCGGCCCGGGAAGCCTTCCCGAAATGGG
CCAATACCCCGGCCAAGGAGCGCGCGCGCCTGATGCGCCGGCTCGGCGAGCTGATCGACCGGAACGTGCCGCACCTGGCG
GAACTGGAGACCCTCGACACCGGCCTGCCGATCCACCAGACGAAGAACGTGCTGATCCCGCGCGCCTCGCACAACTTCGA
GTTCTTCGCCGAAGTCTGCACGCGGATGAACGGGCACAGCTATCCGGTCGACGACCAGATGCTCAACTACACCCTGTACC
AGCCGGTAGGCGTCTGTGGCCTGGTCTCGCCGTGGAACGTACCGTTCATGACCGCCACCTGGAAGACCGCGCCGTGCCTG
GCGCTGGGCAACACGGCGGTGCTGAAGATGTCCGAGCTGTCGCCGCTGACCGCCAACGAGCTGGGCCGCCTGGTGCACGA
GGCGGGCATTCCGCCGGGGGTGTTCAACGTGGTTCAGGGCTACGGCGCCAGCGCCGGCGACGCGCTGGTCCGCCACCGCG
ACGTGCGCGCGGTGTCCTTCACCGGCGGCACCGCCACCGGGCGACGGATCATGGAGGCGGCCGGGATCAAGAAATACTCG
ATGGAACTGGGCGGCAAGTCGCCGGTGCTGGTCTTCGAAGACGCCGACCTCGAGCGGGCGCTGGACGCCGCGCTGTTCAC
CATCTTCTCGCTGAACGGCGAGCGCTGCACCGCCGGCAGTCGCATCTTCGTCCAGGAAAGCGTCTACCCGCAGTTCGTCG
CCGAGTTCGCCGCGCGCGCCAGGCGCCTGATCGTCGGCGATCCGCAGGACCCGAAGACCCAGGTCGGCTCGATGATCACC
CAGGCACACTACGACAAGGTCACCGGCTACATCCGCATCGGCCTCGAGGAAGGCGCCACCCTGGTGGCCGGCGGCCTGGA
GCGTCCGACCGGCCTGCCGGCGCACCTGAGCAAGGGGCAATTCATCCAGCCCACGGTGTTCGCCGACGTGGACAACCGCA
TGCGCATCGCCCAGGAGGAGATCTTCGGCCCGGTGGTCTGCCTGATCCCGTTCAAGGACGAAGCCGAGGCGCTGCGCCTG
GCCAACGACGTGGAATACGGCCTGGCCTCCTACATCTGGACCCAGGACATCGGCAAGGCCCATCGCCTGGCACGCGGCAT
CGAGGCCGGGATGGTCTTCATCAACAGCCAGAACGTGCGCGACCTGCGCCAGCCGTTCGGCGGGGTGAAGGCCTCGGGCA
CCGGACGCGAAGGCGGGGAATACAGCTTCGAGGTATTCGCCGAGATCAAGAACGTGTGTATATCCATGGGCAGCCATCAC
ATCCCCCGCTGGGGCGTGTAG

Protein sequence :
MIKHWINGREVESKDVFENYNPATGELIGEVASGGAAEIDAAVAAAREAFPKWANTPAKERARLMRRLGELIDRNVPHLA
ELETLDTGLPIHQTKNVLIPRASHNFEFFAEVCTRMNGHSYPVDDQMLNYTLYQPVGVCGLVSPWNVPFMTATWKTAPCL
ALGNTAVLKMSELSPLTANELGRLVHEAGIPPGVFNVVQGYGASAGDALVRHRDVRAVSFTGGTATGRRIMEAAGIKKYS
MELGGKSPVLVFEDADLERALDAALFTIFSLNGERCTAGSRIFVQESVYPQFVAEFAARARRLIVGDPQDPKTQVGSMIT
QAHYDKVTGYIRIGLEEGATLVAGGLERPTGLPAHLSKGQFIQPTVFADVDNRMRIAQEEIFGPVVCLIPFKDEAEALRL
ANDVEYGLASYIWTQDIGKAHRLARGIEAGMVFINSQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEIKNVCISMGSHH
IPRWGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 0.0 79
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-69 42
orf17 AAO17183.1 Orf17 Not tested tcd island Protein 2e-63 41
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-66 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-66 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-66 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-66 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-65 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hpcC YP_005983530.1 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase VFG0082 Protein 4e-66 41