Gene Information

Name : cadA (NCGM2_4821)
Accession : YP_005983029.1
Strain : Pseudomonas aeruginosa NCGM2.S1
Genome accession: NC_017549
Putative virulence/resistance : Resistance
Product : putative metal-transporting P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5195815 - 5198037 bp
Length : 2223 bp
Strand : +
Note : similar to GI:116051687; similar to PA14_16660 of P. aeruginosa UCBPP-PA14

DNA sequence :
ATGAGCCACGAACACGCCGACACTTGCTGTCACGGTCACGGTCACGGACATGATCATGGGCACCGCCACGCGCCTCGCCC
GGCGGTGGCCGCCATCGGAACCCTGGCCGGCAACGCCGAGTTGCGCTGGAGCGACCTGCGCATCGAAGCGATGGACTGCC
CGACCGAGGAACGCCTGATCCGCGACGCCCTCGGTCGCCAGCCGGCAGTGGAGTCGCTGGAATTCAACCTGATGCAGCGC
CTGCTGCGCGTCCAGCATCGCTTCGACAGCGTCGAGCCGCTGCAGAAGCTGATCGCCGGCCTCGGCATGCAAGCGGTGCC
GCTGGATGCCGGCGAAAATACCGACGGCCCCTCGCAAGCGCCGGCGAAACCCTGGTGGCCGCTGGCCCTGGCCGGCGCGA
TGGCGCTGGCCTCGGAGATCGTCGAATGGTTCGGCCTGGCGCCGGACTGGGTGGTCGCCGGCCTCGCCCTGCTGGCCATC
CTCGGCGCCGGCCTGCCGACCTACCGCAAGGGCTGGATCGCCCTGAAGAACCGCAACCTGAACATCAACGCCCTGATGAG
CATCGCCGTGACCGGCGCCGTGCTCATCGGCCAGTGGCCGGAAGCGGCGATGGTCAGCGTGCTGTTCGCCATCGCCGAGC
TGATCGAGGCGAAGTCCCTGGATCGCGCGCGCAACGCCATCCGCGGCCTGCTGCAACTGGCTCCGGAACAGGCCACGGTA
CTGGTCGGCGGCGAATGGAAGGAGCTGCCGGCCAAGCAAGTGGAACTGGAAGCCACCGTGCGCGTGAAGCCCGGCGAACG
CATCGCCCTCGACGGCGAGGTGACCAGCGGCCGCTCCAGCGTCAACCAGGCGCCGATCACCGGCGAAAGCCTGCCGGTGG
AGAAGGAGGTCGGCGAGCCGGTGTTCGCCGGCAGCATCAACGGCGAGGGCGCGCTGGAGTACCGCGTCACCCGCCGCGCC
GACGACAGCACCCTGGCCCGGATCATCCACGCCGTGGAGGAAGCCCAGGGTTCCCGCGCACCGACCCAGCGTTTCGTCGA
CAGTTTCGCCCGCGTCTACACCCCGGTGGTATTCCTCATCGCCCTCGCCACCGCGGTGCTACCGCCGCTGCTGTTCGGCG
GCGCCTGGCTGGACTGGATCTACCGCGCCCTGGTGCTGCTGGTGATCGCTTGTCCCTGCGCGCTGGTGATCTCCACCCCG
GTGACCATCGTCAGCGGCCTTTCCGCCGCGGCGCGCCTGGGCATCCTGATCAAGGGCGGGGTGTTCCTCGAACTCGGGCG
CAAGCTGTCCTGGGTCGCCCTCGACAAGACCGGCACCATCACCCATGGCAAACCGCAACAGACCGACTACCTGCCGATCG
CGGAGGCTGACGGGACGGATGCGCGCCTGCTCGCCGCCAGCCTGGCCGCGCGTTCCGACCACCCGGTATCGCGCGCCGTG
GCCAACGCAGCGGAAGAGGACGGCCTTGCCCTGGGCGTGGTCGAGGACCTCGCCGCCCTGCCGGGACGAGGCGTCAGCGG
ACGCATCGACGGCGTCCTCTACCACCTCGGCAACCATCGCCTGGTGGAGGAACTGGGCCTCTGCTCGCCGGCCCTGGAAG
AGCGCCTGGACGCCCTGGAGCGCCAGGGCAAGACGGTCATCGCGCTGTGCGATCCGCAGCGCGTGCGGGCCCTCTTCGCC
GTCGCCGACGGGGTCAAGGACAGCAGCCGCGAGGCGATCCGCGAGCTGCACGCGCTGGACGTGAAGACCCTGATGCTCAC
CGGCGACAACCCGCACACCGCAGCCGCCATCGCTGCCCAGGTAGGCATCGACGCAGCTCGCGGCAACCTCCTGCCGGAAG
ACAAGCTGCGTGAAGTGGAAGCGCGCCAGGCCGACGGCTCGCGGGTCGGCATGGTCGGCGACGGGATCAACGACGCGCCG
GCCCTGGCCCGCGCCGACATCGGCTTCGCCATGGGCGCGGCGGGCACCGACACGGCCATCGAGACCGCCGGCGTCGCGCT
GATGGACGACGACTTGCGCAAGTTGCCGCAATTCGTCCGGCTGTCGCGCACCACCCACGCGATCCTGGTCCAGAACATCA
CCCTGGCCCTGGGCATCAAGGCGGTGTTCCTCGCCCTTACCCTGGCAGGCGAAGGCACCCTGTGGATGGCGGTATTCGCC
GACATGGGCGCCAGCCTGCTGGTGGTGTTCAACGGTCTGCGACTGTTGCGCAAGCGTTTCTGA

Protein sequence :
MSHEHADTCCHGHGHGHDHGHRHAPRPAVAAIGTLAGNAELRWSDLRIEAMDCPTEERLIRDALGRQPAVESLEFNLMQR
LLRVQHRFDSVEPLQKLIAGLGMQAVPLDAGENTDGPSQAPAKPWWPLALAGAMALASEIVEWFGLAPDWVVAGLALLAI
LGAGLPTYRKGWIALKNRNLNINALMSIAVTGAVLIGQWPEAAMVSVLFAIAELIEAKSLDRARNAIRGLLQLAPEQATV
LVGGEWKELPAKQVELEATVRVKPGERIALDGEVTSGRSSVNQAPITGESLPVEKEVGEPVFAGSINGEGALEYRVTRRA
DDSTLARIIHAVEEAQGSRAPTQRFVDSFARVYTPVVFLIALATAVLPPLLFGGAWLDWIYRALVLLVIACPCALVISTP
VTIVSGLSAAARLGILIKGGVFLELGRKLSWVALDKTGTITHGKPQQTDYLPIAEADGTDARLLAASLAARSDHPVSRAV
ANAAEEDGLALGVVEDLAALPGRGVSGRIDGVLYHLGNHRLVEELGLCSPALEERLDALERQGKTVIALCDPQRVRALFA
VADGVKDSSREAIRELHALDVKTLMLTGDNPHTAAAIAAQVGIDAARGNLLPEDKLREVEARQADGSRVGMVGDGINDAP
ALARADIGFAMGAAGTDTAIETAGVALMDDDLRKLPQFVRLSRTTHAILVQNITLALGIKAVFLALTLAGEGTLWMAVFA
DMGASLLVVFNGLRLLRKRF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 67
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 5e-120 48
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 4e-120 48
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-119 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_005983029.1 putative metal-transporting P-type ATPase BAC0298 Protein 0.0 70
cadA YP_005983029.1 putative metal-transporting P-type ATPase BAC0461 Protein 1e-84 42
cadA YP_005983029.1 putative metal-transporting P-type ATPase BAC0100 Protein 5e-61 42