Gene Information

Name : pykA (PAM18_4419)
Accession : YP_005977002.1
Strain : Pseudomonas aeruginosa M18
Genome accession: NC_017548
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4895961 - 4897412 bp
Length : 1452 bp
Strand : +
Note : -

DNA sequence : 
ATGTCCGTTCGCCGCACCAAAATCGTCGCCACCCTCGGCCCAGCCAGCAATTCCCCGGAAGTGCTGGAGCAACTGATCCT
GGCCGGGATCGACGTCGCCCGCCTCAACTTCTCCCACGGCACCCCCGATGAACACCGCGCCCGCGCCAGGCTGGTGCGCG
AACTGGCGGCCAAGCACGGCCGCTTCGTCGCCCTGCTCGGCGACCTGCAAGGACCGAAGATCCGCATCGCCAAGTTCGCC
AACAAGCGCATCGAATTGCAGGTCGGCGACAAGTTCCGCTTCTCCACCAGCCACGCCCGCGACGCCGGTACCCAGGAAGT
GGTCGGCATCGACTACCCGGACCTGGTGAAGGACTGCGGGGTCGGCGATGAACTGCTGCTGGACGACGGCCGGGTGGTGA
TGGTGGTCGAGGAAGTCGCCGCCGACGAACTGCGCTGCCGGGTGCTGATCGGCGGCCCGCTGTCCGACCACAAGGGCATC
AACCGCCGCGGCGGCGGTCTCACCGCGCCGGCGCTGACCGACAAGGACAAGGCCGACATCAAGCTGGCCGCGGACATGGA
CCTGGACTACGTGGCCGTTTCCTTCCCGCGCGACGCCAAGGACATGGAATACGCCCGCCGCCTGCTCACCGAGGCCGGTG
GCAAAGCCTGGCTGGTAGCCAAGATCGAGCGCGCCGAGGCGGTCGCCGACGACGACGCACTCGACGGCCTGATTCGTGCC
AGCGACGCGGTAATGGTGGCCCGTGGCGACCTCGGCGTGGAAATCGGCGATGCCGAGCTGGTCGGCATCCAGAAGAAGAT
CATCCTGCACGCCCGCCGCAACAATAAAGTGGTGATCACCGCGACCCAGATGATGGAGTCGATGATCCACAGCCCGATGC
CGACCCGCGCGGAAGTCTCCGACGTGGCCAACGCCGTGCTCGACTACACCGACGCGGTGATGCTCTCGGCGGAAAGCGCC
GCCGGCGAGTACCCGGTGGAAGCGGTGAAAGCCATGGCCCGCGTCTGCCAGGGCGCCGAGAAGCACCCGACCAGCCAGAA
ATCCAGCCACCGCCTCGGCCAGACTTTCGACCGCTGCGACGAGAGCATCGCCCTGGCGTCGATGTACACGGCCAACCACT
TCCCGGGGATCAAGGCGATCATCTGCCTGACCGAAAGCGGCTTCACCCCGCTGATCATGTCGCGCATCCGCTCGTCGGTA
CCGATTTACGCCTACTCCCCGCACCGCGAGACTCAGGCTCGCGTGGCGATGTTCCGCGGCGTGGAAACCATCCCCTTCGA
CCCGGCGGCGCTGCCGGCGGAGAAGGTCAGCCAGGCCGCGGTCGACGAGTTGCTCAAGCGCGGCGTGGTGACCAAGGGCG
ACTGGGTGATCCTGACCAAGGGCGACAGCTACACCGCCCAGGGCGGCACCAACACCATGAAGGTGCTGCACGTCGGCGAC
CTGCTGGTATAA

Protein sequence : 
MSVRRTKIVATLGPASNSPEVLEQLILAGIDVARLNFSHGTPDEHRARARLVRELAAKHGRFVALLGDLQGPKIRIAKFA
NKRIELQVGDKFRFSTSHARDAGTQEVVGIDYPDLVKDCGVGDELLLDDGRVVMVVEEVAADELRCRVLIGGPLSDHKGI
NRRGGGLTAPALTDKDKADIKLAADMDLDYVAVSFPRDAKDMEYARRLLTEAGGKAWLVAKIERAEAVADDDALDGLIRA
SDAVMVARGDLGVEIGDAELVGIQKKIILHARRNNKVVITATQMMESMIHSPMPTRAEVSDVANAVLDYTDAVMLSAESA
AGEYPVEAVKAMARVCQGAEKHPTSQKSSHRLGQTFDRCDESIALASMYTANHFPGIKAIICLTESGFTPLIMSRIRSSV
PIYAYSPHRETQARVAMFRGVETIPFDPAALPAEKVSQAAVDELLKRGVVTKGDWVILTKGDSYTAQGGTNTMKVLHVGD
LLV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 3e-64 45
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-49 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 7e-49 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 7e-49 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-48 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_005977002.1 pyruvate kinase VFG0479 Protein 3e-49 43