Gene Information

Name : aadE (PPM_1056)
Accession : YP_005958700.1
Strain : Paenibacillus polymyxa M1
Genome accession: NC_017542
Putative virulence/resistance : Resistance
Product : aminoglycoside 6-adenylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.-
Position : 1299623 - 1300477 bp
Length : 855 bp
Strand : +
Note : -

DNA sequence : 
GTGAGAAGTGAACCAGAAATGATGAATATGCTTGTAAAGTTTGCTATGAACGATAAAAGAATACGATTGGTCACGATGGA
AGGATCACGTACAAACTTCAATGTTCCTCCTGATTCATTTCAAGATTATGATATTTCTTACTTTGTAACAGATATGGATT
CTTTCAAGGAAAGTGATCAATGGCTGAACGTGTTTGGGGATAGGCTTATGATGCAAAAACCCGAGGATATGGAGCTTTTT
CCATCAGAACTAGGTAACTGGTTTTCATATATCATTCTTTTTGAGGATGGAAACAAATTAGATCTGACACTGATCCCTAT
AAACGAGGTAGAGGATTATTTTACGAATAGCGATGGTTTAGTTGAGGTTCTGCTCGACAAGGATGTGCTGATCCAAGAGG
AAGTGATCGCAAACGATCATCAATATTGGATTAAAAAGCCCACTGCAAGGGAATTTGATGATTGCTGTAATGAATTTTGG
ATGGTTTCAACTTATATCGTAAAAGGATTGGCGAGAAAAGAAATCCTGTTTGCTATTGACCATTTGAACGAGATTGCACG
ACCTAATTTGTTGCGAATGATGGCTTGGAAGATTGGATCAGAGCAAGGGTACACCTTTAGTGTAGGAAAAAACTATAAAT
TTATAAATCAGTATCTTCCTAATGAAGATTGGAAAAGCCTACTATCGACTTACTCAGAGAACGGCTATCAAGAAATGTGG
CAGTCTTTACTTACTTGTTATTCATTGTTTAGAACATACGCTAAGGCTGTGGCAAGCAGTTTGAAATATGAGTATCCAGA
ATACGATGAAGCCATTACTAGGTACACTGTAAATATTTATAATTCATTGAATTGA

Protein sequence : 
MRSEPEMMNMLVKFAMNDKRIRLVTMEGSRTNFNVPPDSFQDYDISYFVTDMDSFKESDQWLNVFGDRLMMQKPEDMELF
PSELGNWFSYIILFEDGNKLDLTLIPINEVEDYFTNSDGLVEVLLDKDVLIQEEVIANDHQYWIKKPTAREFDDCCNEFW
MVSTYIVKGLARKEILFAIDHLNEIARPNLLRMMAWKIGSEQGYTFSVGKNYKFINQYLPNEDWKSLLSTYSENGYQEMW
QSLLTCYSLFRTYAKAVASSLKYEYPEYDEAITRYTVNIYNSLN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aadE AFJ97264.1 putative adenyltransferase Not tested Not named Protein 3e-78 57
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase Not tested The aminoglycoside resistance gene cluster Protein 8e-83 57
SSU05_0957 YP_001198323.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 8e-81 55
SSU98_0964 YP_001200522.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 8e-81 55
aadE AFJ97257.1 streptomycin aminoglycoside 6-adenyltransferase Not tested Not named Protein 3e-58 54

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadE YP_005958700.1 aminoglycoside 6-adenylyltransferase FN594949.1.gene25.p0 Protein 2e-79 58
aadE YP_005958700.1 aminoglycoside 6-adenylyltransferase AJ489618.1.orf2.gene Protein 1e-61 56
aadE YP_005958700.1 aminoglycoside 6-adenylyltransferase NC_006663.1.orf0.gen Protein 1e-75 55