Gene Information

Name : KPN2242_25511 (KPN2242_25511)
Accession : YP_005957491.1
Strain :
Genome accession: NC_017541
Putative virulence/resistance : Resistance
Product : PbrA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 71001 - 73406 bp
Length : 2406 bp
Strand : +
Note : COG2217 Cation transport ATPase

DNA sequence :
ATGAGCGAATGCGCTTCAAAGGGGTGTGGCTGCACGACTGAGCCGATCATCCAACCCACGGCACCGGCCCCGCTGGCAAC
CGGATCGGCTCAAGCGGTGTACCGCATCGAGAACATGGATTGCCCGACCGAAGAGGCGCTGATCCGAAGCAAACTGGCCG
GTCTGGCGGGGGTGGCGGGTCTTGAATTCAACCTGATGCAACGTACCTTGGCCGTGCGACACGAATTGCCTTCGTTGTCT
CCCGTCGAGCAGGCGCTGAAGGCCATCGGCATGCAAGCTGTGCGCATGGATCAGGCGTCGGCCGAGCAGACGACCAAGCT
GTCCATTGCCAAGATGGATTGCCCGACCGAAGAGACGTTGATCCGCAACAAGCTCGGCACCGTGGCCGGTGTTGCTGATC
TCGATTTCAACCTGATGCAGCGCACGCTGTCGGTACGCCATGCGAACCAGGTTCTGCCAGACGTGCTCGTGGCACTGCAA
GCGCTTGGATTCGAGGCGCAGGTCGTGGACACGGCAGAGGTCGCATCTCCATCCGCCGCCCCTGTGACCACGCCGACCAA
CTGGTGGCCGCTGGGCATCTCCTTGGTCACTGCATCGGCGGCCGAGGCGGTCTACTGGCTCCACAACGGCAATCACTGGT
CGGTTGTCGTTCTGGCGCTTGTCGCGGTCTTCACGGGTGGCCTCTCCACCTACAAGAAGGGGTGGATCGCGCTCAAGAAC
CGTAATCTCAACATGAACGCCCTCATGTCGATTGCGGTCACGGGTGCCATGTTGATCGGCCACTGGCCCGAAGCGGCAAT
GGTGATGGTACTGTTCGCGCTGGCCGAGGTAATCGAAGCCAAATCGCTGGATCGCGCTCGTAACGCTATCCGTGGCCTGC
TCGACCTGACCCCGGAACAAGCCACGGTACAGCAGGCTGACGGCACATGGCGCGAGGTGGGCGCCAAGCAAATCACCATC
GGCGCCCGCGTCCGGGTCAAACCAGGTGAGCGCATCGCCCTTGATGGTGAGGTGCTGGAAGGCCGCTCTGCCGTCAACCA
AGCCCCGATCACGGGTGAAAGCCTCCCGGTCGAAAAATCCCCCGGTGATTCGGTGTTCGCTGGCACGATCAACGAATCCG
GCTCGTTCGAGTACCGCGTCACCGCCTTGGCCAACAACTCCACTTTGGCCCGGATCATTCACGCGGTAGAGGCTGCGCAA
GGTAGTCGTGCGCCGACTCAGCGTTTTGTCGATCAGTTCGCCCGCTGGTACACCCCCGTTGTATTCGGCGTTGCCATCGC
CGTCGCGTTGTTGCCGCCGCTGTTCATGGGTGCGGCATGGCTCGACTGGATCTACCGTGCATTGGTTCTGCTGGTGGTCG
CCTGCCCGTGCGCACTGGTGATCTCTACACCGGTCAGCATCGTCAGCGGCCTGGCCGCCGCCGCCCGCCACGGCATTCTC
ATCAAAGGTGGCGTCTATCTGGAAGAAGGCCGCAAGCTGCGCTGGCTGGCTCTGGACAAGACCGGCACGATCACGCACGG
CAAGCCCGCACAGACCGACTTTGTCACATGGGGCAATGCACTCGCCTCGGACAGCCGCAGCATCGCTGCCAGTCTGGCGG
CCCGCTCGGACCATCCTGTATCCAAGGCGGTGGCACAGGCCGCGCAGACGGACGGGGTTGCCTTGCTCGACGTGGCCGAA
TTCAACGCGCTGCCCGGTCGGGGTGTGCAAGGCCAAATCAACGGTGCGACCTACCATCTGGGCAACCACCGGATGCTCGA
AGAGCTGGGGCAGTGCACACCAGAGCTGGAGCAGCGCATCGCTGCGCTGGAAACCGCTGGCAAGACCGTCGTGATGCTGG
TGGGCGCAAAAGGGGTACATGGCTTATTCGCCGTTGCGGACACCATCAAGGACAGCAGCAAGAGAGCCATCGCCGAGCTG
CATGCTCTGGGCATCAACACCGTGATGTTGACCGGCGATAACCCCCACACGGCACAGGCCATCGCCGCACAAGCCGGCAT
TGACCGCGCGCAAGGCAACCAACTGCCCGACGACAAACTGCGCGAAGTGGAGCAATTGTCCAGAAACGGCAAGGTTGGCA
TGGTCGGTGATGGCATCAACGACGCACCGGCCTTGGCGCGTGCGGACATTGGCTTTGCAATGGGAGCGGCGGGCACAGAT
ACCGCTATTGAAACCGCCGACGTGGCCCTGATGGACGATGACCTGCGCAAGATTCCGACCTTCGTGCGCCTGTCGCGTGC
GACAGCACAGGTGCTGATGCAAAACATTGTGCTGGCCCTTGGCATCAAGGCGGTATTTTTGGTGCTCACCTTCACGGGTC
ACGCGACCATGTGGATGGCTGTGTTCGCCGATATGGGTGCCAGCTTGCTTGTTGTCGGCAACGGCTTGAGGTTGTTGCGC
CGATGA

Protein sequence :
MSECASKGCGCTTEPIIQPTAPAPLATGSAQAVYRIENMDCPTEEALIRSKLAGLAGVAGLEFNLMQRTLAVRHELPSLS
PVEQALKAIGMQAVRMDQASAEQTTKLSIAKMDCPTEETLIRNKLGTVAGVADLDFNLMQRTLSVRHANQVLPDVLVALQ
ALGFEAQVVDTAEVASPSAAPVTTPTNWWPLGISLVTASAAEAVYWLHNGNHWSVVVLALVAVFTGGLSTYKKGWIALKN
RNLNMNALMSIAVTGAMLIGHWPEAAMVMVLFALAEVIEAKSLDRARNAIRGLLDLTPEQATVQQADGTWREVGAKQITI
GARVRVKPGERIALDGEVLEGRSAVNQAPITGESLPVEKSPGDSVFAGTINESGSFEYRVTALANNSTLARIIHAVEAAQ
GSRAPTQRFVDQFARWYTPVVFGVAIAVALLPPLFMGAAWLDWIYRALVLLVVACPCALVISTPVSIVSGLAAAARHGIL
IKGGVYLEEGRKLRWLALDKTGTITHGKPAQTDFVTWGNALASDSRSIAASLAARSDHPVSKAVAQAAQTDGVALLDVAE
FNALPGRGVQGQINGATYHLGNHRMLEELGQCTPELEQRIAALETAGKTVVMLVGAKGVHGLFAVADTIKDSSKRAIAEL
HALGINTVMLTGDNPHTAQAIAAQAGIDRAQGNQLPDDKLREVEQLSRNGKVGMVGDGINDAPALARADIGFAMGAAGTD
TAIETADVALMDDDLRKIPTFVRLSRATAQVLMQNIVLALGIKAVFLVLTFTGHATMWMAVFADMGASLLVVGNGLRLLR
R

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 69
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-114 46
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 4e-115 46
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 4e-115 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPN2242_25511 YP_005957491.1 PbrA BAC0298 Protein 0.0 76
KPN2242_25511 YP_005957491.1 PbrA BAC0100 Protein 7e-62 43
KPN2242_25511 YP_005957491.1 PbrA BAC0455 Protein 4e-89 42