Gene Information

Name : KPN2242_03445 (KPN2242_03445)
Accession : YP_005953174.1
Strain : Klebsiella pneumoniae KCTC 2242
Genome accession: NC_017540
Putative virulence/resistance : Virulence
Product : lysine decarboxylase LdcC
Function : -
COG functional category : -
COG ID : -
EC number : 4.1.1.18
Position : 751059 - 753212 bp
Length : 2154 bp
Strand : +
Note : COG1982 Arginine/lysine/ornithine decarboxylases

DNA sequence :
GTGAATATCATCGCCATCATGGGGCCTCACGGCGTCTACCACAAAGACGAGCCGATCAAAGAACTGGAAGCGGCGCTGCA
GCGCCAGGGCTTCCAGACCATCTGGCCGCAAAACAGCGCCGACCTGCTGCAGTTTATCGAGCACAACCCGCGCATCTGCG
GGGTGATCTTCGACTGGGATGAATACAGCGTCGATCTGTGCAGCGATATCAATCAGCTCAATGAATACCTTCCTCTGTAC
GCCTTTATTAACGCCCACTCGACGATGGATGTCAGCAGTCAGGATTTGCGCATGACGCTGTGGTTCTTCGAATATGCGCT
GGGACTCTCCGAAGAGATCGCCACCCGCATTGGGCAGTACACCCGCGAGTACCTGGAGAATATCACTCCGCCGTTTACCC
GCGCGCTGTTCAACTATGTCCAGGAGGGAAAATATACCTTCTGTACGCCGGGTCATATGGGCGGCAGCGCCTATCAGAAA
AGCCCGGTGGGCTGCCTGTTCTATGATTTTTTTGGCGGGAATACGCTGAAGGCGGATGTCTCGATTTCGGTAACCGAGCT
GGGCTCCCTGCTGGATCATACCGGCCCGCACCTGGAGGCGGAGGAGTATATCGCGCGCGCCTTTGGCGCCGAGCAAAGCT
ATATGGTGACCAACGGCACCTCGACGTCCAATAAAATTGTCGGCATGTACTCGGCGCCCGCCGGCAGCACCCTGCTGATT
GACCGTAACTGTCACAAATCGCTGGCCCACCTGCTGATGATGAGCGATGTGGTTCCCCTGTGGCTGAAGCCGACCCGCAA
CGCGCTGGGGATCCTCGGCGGTATCCCCCGGCGCGAATTTACCCGCGACAGCATTCAGCAGAAAGTGCGCGACACGGGCG
GGGCGCAGTGGCCCGTGCATGCGGTGATCACCAACTCCACCTACGATGGTCTGCTCTATAACACCACCTGGCTTAAGGAG
ACGCTCGATGTCCCGTCGATCCATTTCGATTCCGCCTGGGTGCCCTATACCCATTTCCATCCGATATATCAGGGGAAAAG
CGGTATGAGCGGGGAGCGGATCCCCGGGAAAGTCATCTTCGAGACGCAGTCGACGCATAAGATGCTGGCCGCGCTGTCGC
AGGCCTCGCTGATCCACATTAAAGGCAACTATGATGAAGAGACCTTTAACGAAGCCTTTATGATGCATACCTCTACGTCG
CCGAGCTACCCCATCGTCGCGTCGATTGAGACCGCGGCGGCGATGCTGCGCGGCAACTCCGGTAAACGTCTGATCCAGCG
CTCCATTGAGCGGGCGCTGGACTTCCGCAAAGAGGTGCAGCGACTGCGCGAGGAGTCGGACGGCTGGTTCTTTGATATCT
GGCAGCCGGAAGCCGTGGATAAAGCCGAGTGCTGGCCGGTAGCGCCGGGTGAGGACTGGCACGGTTTCAAAGATGCCGAT
GCGGATCATATGTATCTCGATCCGGTGAAGGTCACCATTCTGACGCCGGGCATGGACGAGCAGGGGAATATGGATGAAGA
GGGGATCCCGGCGGCGCTGGTGGCGAAGTTCCTCGACGAGCGGGGCGTGGTGGTAGAGAAAACAGGCCCCTACAATCTGC
TGTTCCTGTTCAGTATCGGCATCGATAAAACCCGGGCGATGGGGCTGCTGCGCGGCCTGACCGAGTTTAAACGCGCCTAC
GATCTCAATCTGCGGGTGAAAAATATGCTGCCGGATCTGTACGCCGAAGATCCCGACTTCTACCGCAACATGCGGATCCA
GGATCTGGCGCAGGGGATCCACCGCTTGATCCGTCAGCATCAGCTGCCGCAGCTGATGCTCAGCGCCTTTGACGTCCTGC
CGGAAATGAAAATGACGCCGCATCACGCCTGGCAGCGCCAGATCAAGGGGGAGGTGGAAACTATTGAACTGGAGAACCTG
GTGGGGCGGATTTCGGCCAACATGATCCTCCCTTATCCGCCGGGGGTTCCGCTGCTGATGCCGGGAGAGATGATCACCGA
GGAAAGCCGGGCGGTGCTCGATTTTCTGCTGATGCTTTGCTCTATCGGCCGTCATTACCCGGGCTTTGAGACCGATATTC
ACGGCGCCAAGCGCGATGAGGACGGTGTGTATCGGGTACGAGTCTTAAAAAATGACGAAAGGCTTGCGCGTTAA

Protein sequence :
MNIIAIMGPHGVYHKDEPIKELEAALQRQGFQTIWPQNSADLLQFIEHNPRICGVIFDWDEYSVDLCSDINQLNEYLPLY
AFINAHSTMDVSSQDLRMTLWFFEYALGLSEEIATRIGQYTREYLENITPPFTRALFNYVQEGKYTFCTPGHMGGSAYQK
SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARAFGAEQSYMVTNGTSTSNKIVGMYSAPAGSTLLI
DRNCHKSLAHLLMMSDVVPLWLKPTRNALGILGGIPRREFTRDSIQQKVRDTGGAQWPVHAVITNSTYDGLLYNTTWLKE
TLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGERIPGKVIFETQSTHKMLAALSQASLIHIKGNYDEETFNEAFMMHTSTS
PSYPIVASIETAAAMLRGNSGKRLIQRSIERALDFRKEVQRLREESDGWFFDIWQPEAVDKAECWPVAPGEDWHGFKDAD
ADHMYLDPVKVTILTPGMDEQGNMDEEGIPAALVAKFLDERGVVVEKTGPYNLLFLFSIGIDKTRAMGLLRGLTEFKRAY
DLNLRVKNMLPDLYAEDPDFYRNMRIQDLAQGIHRLIRQHQLPQLMLSAFDVLPEMKMTPHHAWQRQIKGEVETIELENL
VGRISANMILPYPPGVPLLMPGEMITEESRAVLDFLLMLCSIGRHYPGFETDIHGAKRDEDGVYRVRVLKNDERLAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 70
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPN2242_03445 YP_005953174.1 lysine decarboxylase LdcC VFG1670 Protein 0.0 63