Gene Information

Name : ureC (KPN2242_20425)
Accession : YP_005956529.1
Strain : Klebsiella pneumoniae KCTC 2242
Genome accession: NC_017540
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 4294884 - 4296587 bp
Length : 1704 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAGTAATATTTCACGCCAGGCCTATGCCGATATGTTCGGCCCCACCGTCGGCGACAAGGTGCGCCTGGCGGATACCGA
GCTGTGGATCGAGGTGGAGGACGATTTGACCACCTACGGGGAAGAGGTCAAATTCGGCGGCGGAAAAGTGATCCGCGACG
GCATGGGCCAGGGGCAGATGCTGGCCGCCGACTGTGTCGACCTGGTGCTCACCAACGCGTTGATCGTCGATCACTGGGGG
ATCGTTAAGGCCGATATCGGCGTGAAGGACGGCCGGATCTTCGCCATCGGCAAAGCCGGTAACCCCGACATCCAGCCCAA
CGTCACCATCCCCATCGGTGCCGCGACGGAAGTGATTGCCGCCGAAGGAAAAATTGTCACCGCCGGCGGGATCGATACCC
ATATTCACTGGATCTGTCCGCAGCAGGCGGAAGAGGCGCTGGTCTCCGGCGTGACCACCATGGTCGGCGGCGGCACCGGC
CCGGCCGCGGGCACCCATGCCACCACCTGCACCCCGGGCCCGTGGTATATCTCACGCATGCTGCAGGCGGCCGACAGCCT
GCCGGTCAATATCGGCCTGCTGGGCAAGGGCAACGTTTCTCAGCCGGATGCCCTGCGCGAGCAGGTGGCGGCGGGCGTTA
TTGGCCTGAAGATCCATGAGGACTGGGGCGCCACCCCGGCGGCGATCGATTGTGCGTTAACCGTCGCCGATGAAATGGAC
ATCCAGGTCGCCCTGCACAGCGACACCCTGAATGAATCCGGTTTTGTGGAAGACACCCTCGCCGCCATCGGCGGGCGCAC
CATCCACACCTTCCATACCGAAGGGGCCGGCGGCGGCCATGCGCCGGACATCATCACCGCCTGCGCCCACCCGAACATTT
TGCCGTCGTCCACCAACCCAACGCTGCCCTACACCCTCAACACCATCGATGAACATCTCGATATGCTGATGGTCTGCCAC
CATCTGGACCCGGACATCGCCGAGGACGTGGCCTTTGCCGAGTCGCGCATTCGCCGGGAAACCATCGCTGCGGAAGACGT
GCTGCACGATCTCGGCGCCTTCTCGCTCACCTCCTCCGATTCGCAGGCCATGGGCCGCGTCGGGGAAGTGATTCTCCGCA
CCTGGCAGGTGGCGCATCGCATGAAGGTGCAGCGCGGAGCGCTGGCGGAGGAGACCGGGAATAACGACAACTTCCGCGTG
AAGCGCTACATCGCCAAATACACCATCAACCCGGCGCTGACCCACGGCATCGCACACGAAGTCGGATCCATTGAGGTGGG
TAAGCTGGCTGACCTCGTGGTCTGGTCACCAGCCTTCTTCGGCGTGAAACCGGCCACCGTGATCAAAGGCGGCATGATCG
CCATCGCGCCGATGGGCGATATCAATGCCTCTATTCCGACCCCGCAGCCGGTGCACTACCGCCCGATGTTTGGCGCGCTG
GGCAGCGCCCGCCATCACTGCCGCCTCACCTTCCTGTCGCAGGCGGCGGCAGCCAATGGCGTTGCCGAGCGGCTGAACCT
GCGCAGCGCGATCGCCGTGGTGAAAGGCTGCCGTACGGTGCAGAAAGCCGACATGGTGCACAACAGTCTGCAGCCTAACA
TCACCGTCGACGCCCAGACCTATGAGGTGCGGGTGGATGGCGAACTTATCACCAGCGAGCCGGCAGACGTTCTGCCGATG
GCGCAACGATATTTTCTGTTTTAA

Protein sequence :
MSNISRQAYADMFGPTVGDKVRLADTELWIEVEDDLTTYGEEVKFGGGKVIRDGMGQGQMLAADCVDLVLTNALIVDHWG
IVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGAATEVIAAEGKIVTAGGIDTHIHWICPQQAEEALVSGVTTMVGGGTG
PAAGTHATTCTPGPWYISRMLQAADSLPVNIGLLGKGNVSQPDALREQVAAGVIGLKIHEDWGATPAAIDCALTVADEMD
IQVALHSDTLNESGFVEDTLAAIGGRTIHTFHTEGAGGGHAPDIITACAHPNILPSSTNPTLPYTLNTIDEHLDMLMVCH
HLDPDIAEDVAFAESRIRRETIAAEDVLHDLGAFSLTSSDSQAMGRVGEVILRTWQVAHRMKVQRGALAEETGNNDNFRV
KRYIAKYTINPALTHGIAHEVGSIEVGKLADLVVWSPAFFGVKPATVIKGGMIAIAPMGDINASIPTPQPVHYRPMFGAL
GSARHHCRLTFLSQAAAANGVAERLNLRSAIAVVKGCRTVQKADMVHNSLQPNITVDAQTYEVRVDGELITSEPADVLPM
AQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 0.0 91
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 0.0 91
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-166 64
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-166 64
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-166 64
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-166 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_005956529.1 urease subunit alpha VFG0270 Protein 2e-153 62