Gene Information

Name : KPN2242_20140 (KPN2242_20140)
Accession : YP_005956474.1
Strain : Klebsiella pneumoniae KCTC 2242
Genome accession: NC_017540
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4241636 - 4242784 bp
Length : 1149 bp
Strand : +
Note : COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence :
ATGTCATCTATCCACACCCTGAGTGTACATAGCGGAACCTTCACCGACAGCCATGGCGCAGTGATGCCGCCGATTTATGC
CACCTCCACTTTTGCTCAGCCAGCGCCGGGGCAGCATACCGGTTATGAATATTCCCGCAGCGGGAATCCCACCCGTCACG
CGCTGGAGACGGCGATCGCCGACCTGGAAAACGGCACGCGCGGCTACGCGTTCGCCTCCGGGCTGGCCGCCATCTCCACC
GTGCTGGAGCTGCTGGATAAGGACAGTCATCTGGTGGCGGTCGATGATGTGTATGGCGGCACTTACCGCCTGCTGGAAAA
CGTTCGCCACCGTAGCGCTGGTCTGCAGGTGAGCTGGGTGAAACCCGACGACCTGGCGGGAATTGAAGCGGCGATCCGCC
CCGATACGCGCATGATCTGGGTGGAAACGCCCACCAACCCGCTGCTGAAGCTCGCGGATCTCAGCGCCATCGCCGCCATC
GCGCGCCGCCATAACCTGATCAGCGTCGCCGATAACACCTTTGCTTCGCCGGCGATCCATCGCCCGCTGGAGCATGGGTT
TGATATTGTGGTGCACTCCGCGACCAAGTACCTCAACGGCCATTCCGATGTCGTCGCCGGCCTGGCGGTGGTTGGCGATA
ACTCCGAGCTCGCGGAAAAGCTTGGCTATCTGCAGAATGCGGTAGGCGGCGTGCTTGACCCGTTCAGCAGCTTCCTGACG
CTGCGCGGCATCCGTACCCTGGCGCTGCGGATGGAGCGCCACAGCGCGAACGCGCTGCAGCTCGCCGAATGGCTGGAACA
GCAGCCGGAAGTGGAGCGAGTCTGGTTTCCCTGGCTGGCTTCGCACCCGCATTATCAGCTGGCGCGCCAGCAAATGGCCC
TGCCCGGCGGCATGATTTCGGTGGTGGTGAAGGGCGATGAAGGTTACGCCGAGCGCATCATCAGCAAGCTGCGCTGGTTT
ACGCTTGCGGAGAGCCTGGGCGGCGTGGAGAGTCTGGTGAGCCAGCCCTTCAGCATGACCCATGCCTCGATCCCGCTGGA
GAAACGCCTGGCGAACGGTATCACACCGCAGCTGATCCGCCTGTCGGTGGGGATCGAAGATCCCAACGATCTGATTGCCG
ACTGGCAGCAGGCGCTGCGGGCGGAGTGA

Protein sequence :
MSSIHTLSVHSGTFTDSHGAVMPPIYATSTFAQPAPGQHTGYEYSRSGNPTRHALETAIADLENGTRGYAFASGLAAIST
VLELLDKDSHLVAVDDVYGGTYRLLENVRHRSAGLQVSWVKPDDLAGIEAAIRPDTRMIWVETPTNPLLKLADLSAIAAI
ARRHNLISVADNTFASPAIHRPLEHGFDIVVHSATKYLNGHSDVVAGLAVVGDNSELAEKLGYLQNAVGGVLDPFSSFLT
LRGIRTLALRMERHSANALQLAEWLEQQPEVERVWFPWLASHPHYQLARQQMALPGGMISVVVKGDEGYAERIISKLRWF
TLAESLGGVESLVSQPFSMTHASIPLEKRLANGITPQLIRLSVGIEDPNDLIADWQQALRAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-80 50
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-81 50
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 8e-58 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPN2242_20140 YP_005956474.1 cystathionine gamma-lyase BAC0207 Protein 7e-68 46