Gene Information

Name : ureC (KPN2242_19600)
Accession : YP_005956368.1
Strain : Klebsiella pneumoniae KCTC 2242
Genome accession: NC_017540
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 4128165 - 4129883 bp
Length : 1719 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGCCAACTATTTCAAGAAAAGAATATGCCAGCCTGTTTGGCCCGACGGTCGGAGATAAAATCCGCCTGGGTGAGACCGA
CCTTTATATCGAAATTGAGAAAGACCTCCGCGGCTATGGTGACGAATCGGTCTATGGTGGCGGTAAATCACTGCGTGATG
GAATGGGATCGAATAATACCTTAACGCGCGATAACGGCGTTCTGGACCTGGTGATTACCAACGTCACGATTCTCGATGCC
AAACTGGGCGTCATTAAGGCCGACGTCGGTATTAAAGATGGCCTGATTGTTGGCATTGGTAAAAGCGGTAACCCGGCCAT
TATGGATGGCGTGACGCAGAATATGATTGTCGGGCTCAGCACTGACGCCATTTCCGGGGAACACTTGATCCTGACCGCGG
CCGGCATCGACAGCCATATCCATCTTATTTCACCGCAGCAGGCATACAGCGCCCTATCGAATGGCGTGGCTACTTTCTTT
GGCGGTGGGATCGGCCCGACGGACGGTACCAACGGAACAACCGTCACCCCAGGCCCCTGGAATATTCGCAAGATGCTGCG
CGCAGTGGAAGGGCTACCGGTCAACGTCGGACTGTTGGGTAAGGGTAACGCGTTTGGGCGTGCTCCGCTGGTTGAACAGA
TTATTGCCGGGGTGGCGGGCCTGAAAGTGCATGAAGACTGGGGAGCCACGCCAAACGCGTTACGTCATTCCCTGCGTATT
GCTGACGAAATGGATATTCAGGTATCGGTGCATACCGATAGCCTTAACGAAGCGGGTTACGTCGAAAACACTATCGAGGC
GTTTGAAGGCCGTACTATTCATACCTTCCATACCGAGGGGGCCGGCGGTGGGCACGCACCGGATATCATCAAGGTGGCCA
GCCAGTTAAACGTGCTGCCCAGCTCCACTAACCCTACCCTTCCATTCGGCATCAACACCCAGGCTGAACTGTTCGACATG
ATCATGGTGTGTCACAACCTGAACCCAAACGTGGCTGCGGACGTCTCCTTCGCTGAAAGCCGCGTCCGTCCGGAAACTAT
CGCGGCGGAAAACGTGCTGCATGACATGGGCGTAATCTCGATGTTTTCGAGCGACTCTCAGGCGATGGGACGCGTCGGAG
AAAACTGGCTGCGCGTTGTGCAGACAGCCCATGCCATGAAAGTCGCCCGCGGGAAACTGCCAGAAGACAGCGACGGCAAC
GATAACTTCCGGGTATTGCGCTACGTTGCCAAGCTGACCATCAATCCGGCTATTGCGCATGGCGTAAGCCATATCATCGG
CTCAATTGAAGTGGGCAAGATGGCCGATCTGGTTTTATGGGACCCGCGTTCTTTCGGTGCGAAGCCGAAGATGGTGATCA
AGGGCGGCATGATCAACTGGGCCCTGATGGGCGATCCAAACGCATCGCTGCCGACCCCGCAGCCGGTATTCTATCGCCCG
ATGTTTGGTGCCATGGGGAAAACCCTGCAAGACACCTGCGCGACTTTCGTGTCTCAAGCCGCGCTGGATGATGGTGTCAA
AGAGAAAGCCGGCCTTGAGCGTCAGGTTATCGCTATCAACAATTGCCGCTCAGTAACCAAGCGTGATTTGGTACGTAACT
CCGCCACGCCGCATATCGAAGTTGATCCGGAAACTTTCGCCGTGAAAGTGGATGGTGAACATGCCACCTGCAACCCCGTC
ACAACAGCGGTAATGAACCAAAAATATTTCTTTGGCTAA

Protein sequence :
MPTISRKEYASLFGPTVGDKIRLGETDLYIEIEKDLRGYGDESVYGGGKSLRDGMGSNNTLTRDNGVLDLVITNVTILDA
KLGVIKADVGIKDGLIVGIGKSGNPAIMDGVTQNMIVGLSTDAISGEHLILTAAGIDSHIHLISPQQAYSALSNGVATFF
GGGIGPTDGTNGTTVTPGPWNIRKMLRAVEGLPVNVGLLGKGNAFGRAPLVEQIIAGVAGLKVHEDWGATPNALRHSLRI
ADEMDIQVSVHTDSLNEAGYVENTIEAFEGRTIHTFHTEGAGGGHAPDIIKVASQLNVLPSSTNPTLPFGINTQAELFDM
IMVCHNLNPNVAADVSFAESRVRPETIAAENVLHDMGVISMFSSDSQAMGRVGENWLRVVQTAHAMKVARGKLPEDSDGN
DNFRVLRYVAKLTINPAIAHGVSHIIGSIEVGKMADLVLWDPRSFGAKPKMVIKGGMINWALMGDPNASLPTPQPVFYRP
MFGAMGKTLQDTCATFVSQAALDDGVKEKAGLERQVIAINNCRSVTKRDLVRNSATPHIEVDPETFAVKVDGEHATCNPV
TTAVMNQKYFFG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-150 58
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-150 58
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-139 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-139 57
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-139 57
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-139 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_005956368.1 urease subunit alpha VFG0270 Protein 2e-148 58