Gene Information

Name : KPN2242_17925 (KPN2242_17925)
Accession : YP_005956034.1
Strain : Klebsiella pneumoniae KCTC 2242
Genome accession: NC_017540
Putative virulence/resistance : Virulence
Product : lactaldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3779551 - 3781071 bp
Length : 1521 bp
Strand : -
Note : COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGCGTTATGCACATCCTGGCCAGCCCGGCGCCATGGTTTCATTTAAATCGGCTTACGGCAACTTTATTGACGGTAGATT
TGTCGAGCCGCTGAGCGGTGAATTCTTTATGAATACTTCGCCGGTCGACGGCAGCAACATTGCGCAGTTTCCCCGCTCGG
ATGCCAGAGACATTGACTTCGCCCTCGACGCTGCCCATCGCGCGGCGCCGGCGTGGGGTAAAACCTCAGTGCAACAGCGC
TCCAGGCTGCTGCTGCAGGTCGCCGATCGTATTGAACAGCATCTGGAATATCTGGCGGTGGCGGAGAGCTGGGACAATGG
GAAACCGATCCGCGAAACCCTGAATGCCGACCTGCCGCTGGCGGTGGATCATTTTCGCTACTTCGCCGGCTGCCTGCGCG
CTCAGGAGGGAAGCACCGCCGAGATTGACGAAACCACGGTGGCCTATCATTTCCATGAACCGCTGGGGGTGGTCGGGCAG
ATTATCCCGTGGAACTTCCCGCTGCTGATGGCCGCGTGGAAGCTGGCCCCGGCCCTGGCGGCGGGGAACTGCGTGGTGCT
CAAGCCGGCGGAACAGACGCCGCTAAGCATTACCCTGCTGCTGGAGCTGATCGGCGATCTGTTCCCGGCCGGGGTGCTTA
ACGTGGTGCAGGGTTTCGGCAAAGAGGCGGGCGAGGCGCTGGCCACCAGCAAGCGTATCGCCAAGCTGGCGTTTACCGGC
TCCACGCCGGTCGGGCGGCATATTCTCGCCTGCGCGGCGGAAAATATTATCCCCTGCACCGTCGAGCTGGGGGGGAAATC
GCCCAACATCTACTTCGCCGACGTGATGGACGGAGAAGAGGAATTTATCGAGAAGGTGGTGGAGGGGCTGGTGCTCGGCT
TCTTCAACCAGGGTGAGGTCTGTACCTGCCCGTCGCGGGCGCTGATCCATGAATCCATCTATGAGCCCTTTATGGCACGG
GTCATGGAGAAGGTGGCGCAGATCCGCCGCGGCGATCCGTTAGATACCGACACCATGATCGGCGCTCAGGCTTCCCGCCA
GCAGTTCGACAAGATCCTCTCCTATATTCAGATTGCCCGGGAAGAGGGTGGGCAAATTCTGACCGGAGGCGAGCGGGCGG
CTATCGCGCCGGCGCTGGATAATGGTTTTTATATTCAGCCCACGCTGATTAAAGGTCGCAACGATATGCGCTCCTTCCAG
GAGGAGATCTTTGGGCCGGTGATCGGGGTGACCACCTTTAAGGACGAAGCGGAAGCGCTGGCTATCGCCAATGAGACCCA
GTTTGGTCTCGGCGCCGGGGTGTGGACGCGGGATACCAACCTCGCCTATCGCATGGGTCGCGGCATTAAAGCCGGTCGCG
TGTGGACCAACTGCTATCATGTCTACCCGGCGCATGCGGCGTTCGGCGGCTATAAACAGTCCGGCGTCGGGCGGGAAACG
CACAAGATGGCGCTGGATGCCTATCAGCAAACCAAAAACCTGCTGGTGAGCTACGGCACCGCGCCGCTGGGCCTGTTCTG
A

Protein sequence :
MRYAHPGQPGAMVSFKSAYGNFIDGRFVEPLSGEFFMNTSPVDGSNIAQFPRSDARDIDFALDAAHRAAPAWGKTSVQQR
SRLLLQVADRIEQHLEYLAVAESWDNGKPIRETLNADLPLAVDHFRYFAGCLRAQEGSTAEIDETTVAYHFHEPLGVVGQ
IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPLSITLLLELIGDLFPAGVLNVVQGFGKEAGEALATSKRIAKLAFTG
STPVGRHILACAAENIIPCTVELGGKSPNIYFADVMDGEEEFIEKVVEGLVLGFFNQGEVCTCPSRALIHESIYEPFMAR
VMEKVAQIRRGDPLDTDTMIGAQASRQQFDKILSYIQIAREEGGQILTGGERAAIAPALDNGFYIQPTLIKGRNDMRSFQ
EEIFGPVIGVTTFKDEAEALAIANETQFGLGAGVWTRDTNLAYRMGRGIKAGRVWTNCYHVYPAHAAFGGYKQSGVGRET
HKMALDAYQQTKNLLVSYGTAPLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-154 66
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-161 64
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-161 64
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-161 64
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-160 64
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KPN2242_17925 YP_005956034.1 lactaldehyde dehydrogenase VFG0082 Protein 7e-155 66