Gene Information

Name : entE (KPN2242_05920)
Accession : YP_005953669.1
Strain : Klebsiella pneumoniae KCTC 2242
Genome accession: NC_017540
Putative virulence/resistance : Virulence
Product : enterobactin synthase subunit E
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.58
Position : 1252444 - 1254051 bp
Length : 1608 bp
Strand : +
Note : COG1021 Peptide arylation enzymes

DNA sequence : 
ATGATTGCATTTACCCGTTGGCCGGAAGAGTTTGCGGCCCGCTATCGTCAAAAAGGCTACTGGCAGGATCTGCCGTTAAC
CAATCTGATCACCCGTCACGCGGAAAACGACGCCGTGGCGATTATCGATGGCGAGCGGCAGATTAGCTACCGCCAGTTTA
ACCAGCTGGTGGACAACCTCGCCTGCTCGCTGCAGCGCCAGGGACTGAAGCGCGGGGAGACCGCGCTGGTGCAGTTGGGC
AATGTCGCCGAGTTTTACATGACCTTCTTTGCGCTGCTGCGCATCGGCGTCGCGCCAGTGAACGCTTTGTTCAGCCACCA
GCGCAGCGAACTTAACGCCTACGCCGCGCAGATTAAACCGGCGCTGCTGATTGCCGATCGCGAGCACGCGCTGTTTGCTG
ACGATAGCTTTCTCCACGCGTTTATCGCGGAACATCCTTCCCTGCGCGTCGCACTGTTGCGTAACGACGGCGGCGAGCGC
GATCTGGCGACGGAGATTAACCGCCCGGCGGATAACTTTATCGCCAATCCAACCCCTGCCGACGAAGTGGCCTTTTTCCA
GCTCTCCGGCGGCAGCACCGGGACGCCGAAGCTTATCCCACGCACCCATAACGATTACGACTACAGTATCCGCCGCAGCA
ACGAGATCTGCGGGATTAACGCTGAAACGCGCTACCTCAACGCGCTGCCGGCGGCGCATAACTATGCGATGAGTTCCCCG
GGCTCGCTCGGCGTCTTCCTCGCCGGCGGGCGGGTGATCCTCGCCGCTGACCCGAGCGCCACGCTCTGTTTCCCGCTGAT
CGAAAAACATCAGATCAACGTTGCCTCGCTGGTGCCGCCGGCGGTCAGCCTGTGGCTGCAGGCGATTCACGAATGGGGCA
GCAACGCCCAGTTGCAATCGCTGCAGCTGTTGCAGGTCGGCGGCGCGCGCCTGTCAGCGACCCTCGCCGCGCGCATTCCG
GCGGAAATCGGCTGCCAGCTGCAGCAGGTGTTCGGCATGGCGGAGGGGCTGGTGAATTACACCCGCCTTAACGATAGCCC
GGAGCGGATCATCAATACCCAGGGCTGTCCGATGTGCCCGGACGATGAAGTGTGGGTGGCGGACGCCGACGGCAACCCGC
TGCCGCGCGGCGAAGTTGGCCGTCTGATGACCCGCGGTCCTTATACCTTCCGCGGCTATTACAACAGTCCGCAACATAAC
GCTGAAGCCTTTGATGCCGATGGATTTTACTGCTCCGGTGATCTGATTTCGATCGATGAAGATGGCTATATCACCGTCCA
GGGCCGGGAAAAAGATCAGATCAACCGCGGCGGCGAGAAGATCGCCGCTGAAGAGATCGAAAACCTGCTGCTGCGCCATG
AGGCGGTGATCCACGCCGCGCTGGTCAGCATCGAAGACAATCTGCTGGGCGAGAAAAGCTGCGCTTATCTGGTGGTGACC
TCGCCGCTGCGCGCCGTCGCCGTGCGCCGCTTCCTGCGCGAGCAGGGGGTGGCGGAATTTAAACTGCCGGACCGCGTGGA
GTGCGTTGCCGCGCTGCCGCTGACGCCGGTGGGCAAAGTCGATAAAAAACAATTACGTCAGTGGCTGGCCGAAGGCAAGC
TGGGCTGA

Protein sequence : 
MIAFTRWPEEFAARYRQKGYWQDLPLTNLITRHAENDAVAIIDGERQISYRQFNQLVDNLACSLQRQGLKRGETALVQLG
NVAEFYMTFFALLRIGVAPVNALFSHQRSELNAYAAQIKPALLIADREHALFADDSFLHAFIAEHPSLRVALLRNDGGER
DLATEINRPADNFIANPTPADEVAFFQLSGGSTGTPKLIPRTHNDYDYSIRRSNEICGINAETRYLNALPAAHNYAMSSP
GSLGVFLAGGRVILAADPSATLCFPLIEKHQINVASLVPPAVSLWLQAIHEWGSNAQLQSLQLLQVGGARLSATLAARIP
AEIGCQLQQVFGMAEGLVNYTRLNDSPERIINTQGCPMCPDDEVWVADADGNPLPRGEVGRLMTRGPYTFRGYYNSPQHN
AEAFDADGFYCSGDLISIDEDGYITVQGREKDQINRGGEKIAAEEIENLLLRHEAVIHAALVSIEDNLLGEKSCAYLVVT
SPLRAVAVRRFLREQGVAEFKLPDRVECVAALPLTPVGKVDKKQLRQWLAEGKLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-86 42
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-86 42
ybtE CAA21394.1 - Virulence HPI Protein 5e-86 42
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 4e-86 42
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 3e-86 42
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-86 42
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-86 42
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 5e-86 42
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 5e-86 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
entE YP_005953669.1 enterobactin synthase subunit E VFG0932 Protein 0.0 82
entE YP_005953669.1 enterobactin synthase subunit E VFG0168 Protein 5e-105 45