Gene Information

Name : TIB1ST10_10280 (TIB1ST10_10280)
Accession : YP_005945605.1
Strain : Propionibacterium acnes 6609
Genome accession: NC_017535
Putative virulence/resistance : Virulence
Product : ATP-dependent protease (Clp chaperone)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2192143 - 2194716 bp
Length : 2574 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGGACACCAATCTCACCACGATGAGCCGTGACGCGGTCACCGCCGCTACTCGGCATGCGTTGGCCCACGGGAACCCATC
CGTGGAGCCCTCGCATCTTCTTCACGCACTGTTCACGATCCCAGACAACACTGTCAGTCCGTTGGTAGCTGGCTTGGGGA
TTGATCCTCAGCAGGTCGACGCCGTCGCTACCGCAGCGATGCGCTCCCTTCCGTCAAGTACCGGCGCCTCAGTAGCTCAG
CCGCAGCTGTCCGGGGCCTTCGCCCGAGTCATCGCCGACGCGCAGAACCGTGCCGAGGCCATGGGCGATTCCTTCGTCGC
TACCGAGCATCTTCTTATTTCGCTGACGGCGGTTCCCTCCGACGTCCAGAACGGCCTGGCAGGGCTCGGCCTCAAGCCTG
ACTCCCTCGCGGCGGCCTTCAATGAAGGTCGTGGAGACCGTCGTGTCACCTCCGAGGAGTCCGAGGGAGGCGAATCGGCT
CTCGCCAAGTACTCCGTCGATCTCACCGAGCGCGCCCGTGCCGGCAAGCTCGACCCCGTCATTGGTCGTGACCAGGAGAT
TCGCCGCGTCGTCCAGGTGTTGGCGCGACGCACTAAGAACAACCCGGTCCTTATCGGTGAACCGGGGGTCGGCAAGACTG
CCGTCGTCGAGGGGTTGGCTCAGCGCGTCGTCGCCGGGGACGTTCCCGACTCTCTCAAAGGGCGTCGCGTCGTCTCTTTG
GATCTGTCCTCCATGGTTGCCGGGGCTAAATACCGCGGCGAGTTTGAGGAGCGCCTCAAGGCCGTCCTCAACGAGATCAA
GGAGGCCGAGGGGCAGATCATTACCTTTATCGATGAGCTGCACACCGTCGTCGGCGCCGGGGCTTCCGGAGAGGGAGCAA
TGGACGCTGGCAATATGCTCAAGCCGATGCTGGCCCGTGGCGAGCTGCGAATGATCGGTGCCACTACCCTCGACGAGTAC
CGCGAGCATATTGAGAAGGACCCAGCTCTGGAGCGTCGTTTCCAGCAGGTCTTTGTCGGTGAACCGTCGGTTGAGGACAC
TATTGCCATCCTGCGCGGCTTGCGAGAGCGCTACGAGGCCCACCACAAGGTGCGTATTACTGACGGAGCCCTTGTCGCGG
CCGCCAGCTTGTCTCACCGGTACATCACCGCCCGTCAGCTTCCTGACAAGGCCATTGACCTTATCGACGAGGCTGCGTCT
CGGCTGCGCATGGAGATTGACTCCTCTCCGGAGGAGATCGACACCCTGCGCCGTGAAGTCGACCGCATGAAGATGGAGAT
CTTCGCCGTCGAGAAGGAGGACGACCCGGCCAGCCAGCAGCGCCTAACGAGGTTGCGCGCTGACATGGCTGACAAGGAGG
AGACCCTGCGCGGCCTGGAGTCGCGCTGGGAGGCTGAGAAGGCTGGTCTCAACAAGGTCGGTGAGCTCAAGACAAGGATT
GACGAGTTGCGGACTGCGGCCGACAAGTACCAGCGCGAGGGCGACTTCGGGCGAGCGTCCGAGATCCTCTACGGTCAGAT
TCCCGGCCTTGAGAAGGAGATGGAGGCTGCTGCCAAGGCTGAGGAGGAGACCCCACGGATGGTGTCCGAGGAGGTCGGTA
CCTCCGACATTGCCGAGGTTGTTTCCTCGTGGACCGGCATCCCCGTGGGGCGGATGATGCAAGGCGAGCAGGAGAAGCTG
CTCCATATGGAGGAGCGGCTGCACGAACGTCTTATTGGTCAGGATCGAGCTGTCAAGACCGTCTCGGATGCGGTGCGTCG
CTCCCGGGCCGGAATCAGCGACCCGAACCGTCCGACTGGCTCGTTCCTCTTCCTGGGCCCCACGGGCGTCGGCAAGACCG
AGTTGGCCAAGTCCCTGGCGGAGTTCCTCTTCGACGACGAGACCGCTCTGGTGCGTATTGACATGAGTGAGTACATGGAG
AAGCACTCCGTCTCACGTCTGGTCGGTGCCCCTCCGGGTTACATCGGTTACGAAGAGGGCGGTCAGCTTACCGAAGCTGT
GCGGCGTCGCCCCTACTCGGTTATCTTGCTCGACGAGGTGGAAAAGGCTCATTCCGACGTCTTTAACATTTTGTTGCAGG
TGCTCGACGACGGTCGTCTGACTGACGGCCAAGGACGCACGGTGGATTTCCGCAACACCATTTTGGTCTTGACGAGCAAT
CTGGGTAGCCAATTCCTGTCAGACGCGAGCCTTGATGACCATGCTAAGCGTGAGGCCGTCATGGGGGCGGTGCGTCAGGC
GTTTCGACCCGAGTTCCTGAATCGACTCGACGATGTGGTCATGTTCGACCCGTTGTCGATGGCCGATCTGGGACGGATCG
TCGAGACGAACCTGGCTAAGCTCAATTCACGGCTGGCCGAGCGGCGCATCACCATTGCCGTGACCGACGCCGGTAAGGAC
TGGCTGGCCATGGCGGGTTTCGACCCGATCTACGGTGCCCGACCACTGCGTCGCCTGATGCAGACCACCATCGATGATCA
GCTGGCTCGCAAGGTGTTGTCTGGGCAAGTGCAGGAGGGCGATACGGCGACCTTTGACATCAACGAGGCCGGTGACGGTT
TGGTGATTCTCTGA

Protein sequence :
MDTNLTTMSRDAVTAATRHALAHGNPSVEPSHLLHALFTIPDNTVSPLVAGLGIDPQQVDAVATAAMRSLPSSTGASVAQ
PQLSGAFARVIADAQNRAEAMGDSFVATEHLLISLTAVPSDVQNGLAGLGLKPDSLAAAFNEGRGDRRVTSEESEGGESA
LAKYSVDLTERARAGKLDPVIGRDQEIRRVVQVLARRTKNNPVLIGEPGVGKTAVVEGLAQRVVAGDVPDSLKGRRVVSL
DLSSMVAGAKYRGEFEERLKAVLNEIKEAEGQIITFIDELHTVVGAGASGEGAMDAGNMLKPMLARGELRMIGATTLDEY
REHIEKDPALERRFQQVFVGEPSVEDTIAILRGLRERYEAHHKVRITDGALVAAASLSHRYITARQLPDKAIDLIDEAAS
RLRMEIDSSPEEIDTLRREVDRMKMEIFAVEKEDDPASQQRLTRLRADMADKEETLRGLESRWEAEKAGLNKVGELKTRI
DELRTAADKYQREGDFGRASEILYGQIPGLEKEMEAAAKAEEETPRMVSEEVGTSDIAEVVSSWTGIPVGRMMQGEQEKL
LHMEERLHERLIGQDRAVKTVSDAVRRSRAGISDPNRPTGSFLFLGPTGVGKTELAKSLAEFLFDDETALVRIDMSEYME
KHSVSRLVGAPPGYIGYEEGGQLTEAVRRRPYSVILLDEVEKAHSDVFNILLQVLDDGRLTDGQGRTVDFRNTILVLTSN
LGSQFLSDASLDDHAKREAVMGAVRQAFRPEFLNRLDDVVMFDPLSMADLGRIVETNLAKLNSRLAERRITIAVTDAGKD
WLAMAGFDPIYGARPLRRLMQTTIDDQLARKVLSGQVQEGDTATFDINEAGDGLVIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-108 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TIB1ST10_10280 YP_005945605.1 ATP-dependent protease (Clp chaperone) VFG2084 Protein 1e-111 43