Gene Information

Name : phoP (lmo4a_2503)
Accession : YP_005927496.1
Strain : Listeria monocytogenes L99
Genome accession: NC_017529
Putative virulence/resistance : Virulence
Product : two-component response regulator
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2561878 - 2562588 bp
Length : 711 bp
Strand : -
Note : Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence :
TTGGTAAAAATTCTTGTAGTTGATGATGAAGCTTCTATTGTTACGTTACTGCAATTTAATATTGAAAAAGCTGGGTTTGA
TGTGGTAACAGCAGAAGACGGCAGATCCGGATACGAACTCGCTTTGTCCGAAAAACCAGATTTAATTGTGCTTGATTTAA
TGCTTCCTGAGATGGACGGAATCGAAGTAACAAAAAAACTTCGCCAAGATAAAGTAAATGTGCCAATTTTAATGTTAACG
GCAAAAGATGAAGAATTAGATAAAATTATCGGGCTGGAACTTGGAGCAGATGACTATATGACTAAACCGTTTAGCCCAAG
AGAAGTAGTTGCAAGAATTAAAGCAATCTTGCGTCGAACAGAAGGAAAAGCCGAAATCATAGAAGAAATAACCGAAGATT
CGGAAGCTACGATATTAATTGGTGATTTGAAAATTTTGCCAGATAGTTATGAAGTGTATTTACAAGATGATTTACTTGAT
TTAACGCCAAAAGAATTTGAGTTATTGCTATTCTTGGCAAATCATCGCGGAAAAGTTTTTTCCAGAGATCAATTACTTGA
TACCGTGTGGAATTATGACTACGTTGGAGAAACCCGAATCGTAGACGTTCATGTCAGCCATTTGCGCGATAAAATTGAAC
TAGATACAAAACAACCTAAATACATCAAAACAATTCGTGGCTTTGGTTACAAAATGGAGAACGTGAAATAA

Protein sequence :
MVKILVVDDEASIVTLLQFNIEKAGFDVVTAEDGRSGYELALSEKPDLIVLDLMLPEMDGIEVTKKLRQDKVNVPILMLT
AKDEELDKIIGLELGADDYMTKPFSPREVVARIKAILRRTEGKAEIIEEITEDSEATILIGDLKILPDSYEVYLQDDLLD
LTPKEFELLLFLANHRGKVFSRDQLLDTVWNYDYVGETRIVDVHVSHLRDKIELDTKQPKYIKTIRGFGYKMENVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 2e-41 42
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 2e-41 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoP YP_005927496.1 two-component response regulator HE999704.1.gene2815. Protein 4e-106 98
phoP YP_005927496.1 two-component response regulator NC_013450.8614421.p0 Protein 6e-68 60
phoP YP_005927496.1 two-component response regulator NC_007793.3914279.p0 Protein 6e-68 60
phoP YP_005927496.1 two-component response regulator NC_002745.1124361.p0 Protein 6e-68 60
phoP YP_005927496.1 two-component response regulator NC_009782.5559369.p0 Protein 6e-68 60
phoP YP_005927496.1 two-component response regulator NC_002951.3237708.p0 Protein 6e-68 60
phoP YP_005927496.1 two-component response regulator NC_003923.1003749.p0 Protein 5e-68 60
phoP YP_005927496.1 two-component response regulator NC_002758.1121668.p0 Protein 6e-68 60
phoP YP_005927496.1 two-component response regulator NC_009641.5332272.p0 Protein 6e-68 60
phoP YP_005927496.1 two-component response regulator NC_002952.2859905.p0 Protein 8e-68 59
phoP YP_005927496.1 two-component response regulator NC_007622.3794472.p0 Protein 7e-68 59
phoP YP_005927496.1 two-component response regulator AE016830.1.gene1681. Protein 2e-69 56
phoP YP_005927496.1 two-component response regulator NC_012469.1.7685629. Protein 1e-55 54
phoP YP_005927496.1 two-component response regulator NC_012469.1.7686381. Protein 1e-60 50
phoP YP_005927496.1 two-component response regulator AE000516.2.gene3505. Protein 2e-38 44
phoP YP_005927496.1 two-component response regulator AF162694.1.orf4.gene Protein 1e-37 43
phoP YP_005927496.1 two-component response regulator CP001485.1.gene721.p Protein 2e-36 42
phoP YP_005927496.1 two-component response regulator CP001918.1.gene5135. Protein 3e-29 42
phoP YP_005927496.1 two-component response regulator CP004022.1.gene3215. Protein 9e-37 41
phoP YP_005927496.1 two-component response regulator FJ349556.1.orf0.gene Protein 6e-42 41
phoP YP_005927496.1 two-component response regulator EU250284.1.orf4.gene Protein 4e-39 41
phoP YP_005927496.1 two-component response regulator BAC0533 Protein 5e-33 41
phoP YP_005927496.1 two-component response regulator NC_002695.1.915041.p Protein 2e-32 41
phoP YP_005927496.1 two-component response regulator CP000647.1.gene4257. Protein 5e-33 41
phoP YP_005927496.1 two-component response regulator CP000034.1.gene3834. Protein 2e-32 41
phoP YP_005927496.1 two-component response regulator CP001138.1.gene4273. Protein 8e-33 41
phoP YP_005927496.1 two-component response regulator CP000034.1.gene3671. Protein 2e-39 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoP YP_005927496.1 two-component response regulator VFG1563 Protein 1e-41 42
phoP YP_005927496.1 two-component response regulator VFG1702 Protein 9e-42 42
phoP YP_005927496.1 two-component response regulator VFG1386 Protein 2e-39 42
phoP YP_005927496.1 two-component response regulator VFG1389 Protein 3e-33 41