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Name : ureC (MRGA423_11560) Accession : YP_005923082.1 Strain : Mycobacterium tuberculosis RGTB423 Genome accession: NC_017528 Putative virulence/resistance : Virulence Product : urease subunit alpha Function : - COG functional category : - COG ID : - EC number : 3.5.1.5 Position : 2097538 - 2099130 bp Length : 1593 bp Strand : + Note : COG0804 Urea amidohydrolase (urease) alpha subunit DNA sequence : GTGTTCGGCGGCGGCAAGGTGCTGCGCGAGTCCATGGGCCAGGGCCGTGCGAGCCGGGCCGACGGTGCCCCCGACACCGT GATCACCGGTGCGGTGATCATCGACTACTGGGGAATCATCAAGGCCGACATCGGGATTCGCGATGGCCGCATCGTCGGGA TCGGAAAGGCCGGCAATCCCGACATCATGACAGGTGTGCATCGGGATCTCGTCGTCGGGCCGTCCACCGAAATCATCAGC GGCAACCGTCGAATCGTCACCGCAGGCACCGTCGACTGTCACGTGCACTTGATCTGTCCGCAGATCATCGTCGAAGCCTT GGCCGCGGGCACCACCACGATCATCGGCGGTGGCACCGGACCCGCCGAGGGCACCAAGGCCACCACAGTCACTCCCGGCG AGTGGCACCTGGCCCGGATGCTGGAGTCACTGGACGGTTGGCCGGTGAACTTCGCGCTGCTCGGCAAGGGAAACACCGTG AATCCCGACGCACTGTGGGAACAGTTGCGCGGTGGCGCATCGGGTTTCAAACTCCACGAAGACTGGGGATCGACCCCGGC GGCCATCGACACCTGCTTGGCGGTCGCCGACGTGGCCGGGGTGCAGGTTGCGCTGCACTCCGACACTCTCAATGAGACCG GATTCGTCGAGGACACCATCGGCGCGATCGCCGGACGTTCGATTCACGCCTACCACACCGAGGGCGCCGGCGGCGGGCAC GCACCGGACATCATTACCGTCGCGGCGCAACCGAATGTACTGCCCAGCTCGACCAATCCGACCCGCCCGCATACGGTGAA CACCCTTGACGAGCATCTCGACATGCTGATGGTGTGCCACCACCTCAACCCCCGGATCCCGGAGGACCTCGCGTTTGCCG AAAGCCGGATCCGACCGTCCACCATTGCGGCAGAAGATGTGTTGCACGATATGGGGGCAATCTCGATGATTGGCAGCGAT TCCCAGGCGATGGGCCGTGTCGGCGAGGTGGTGCTGCGCACCTGGCAGACCGCGCACGTGATGAAAGCCCGCCGCGGGGC ACTGGAAGGTGACCCGTCTGGTAGCCAAGCCGCCGACAACAACCGGGTCCGCCGCTACATCGCCAAATACACCATCTGCC CGGCCATCGCACACGGCATGGATCACCTGATCGGTTCGGTGGAGGTGGGAAAGTTGGCCGACCTGGTGTTGTGGGAGCCG GCGTTTTTCGGGGTTCGCCCGCACGTCGTGCTCAAAGGTGGGGCGATCGCCTGGGCAGCGATGGGCGATGCGAACGCGTC AATCCCGACCCCGCAACCGGTGCTCCCGCGACCGATGTTCGGCGCGGCCGCGGCAACCGCGGCGGCGACCTCGGTGCACT TCGTCGCGCCGCAATCCATCGACGCGCGCCTGGCGGACCGGCTCGCGGTCAATCGGGGACTAGCGCCGGTGGCCGACGTG CGCGCAGTGGGCAAGACCGACCTGCCGCTCAATGATGCCCTACCGAGCATCGAGGTCGATCCCGACACCTTCACCGTGCG AATCGACGGCCAGGTGTGGCAACCGCAGCCGGCCGCCGAACTACCTATGACACAACGGTATTTCCTGTTCTAA Protein sequence : MFGGGKVLRESMGQGRASRADGAPDTVITGAVIIDYWGIIKADIGIRDGRIVGIGKAGNPDIMTGVHRDLVVGPSTEIIS GNRRIVTAGTVDCHVHLICPQIIVEALAAGTTTIIGGGTGPAEGTKATTVTPGEWHLARMLESLDGWPVNFALLGKGNTV NPDALWEQLRGGASGFKLHEDWGSTPAAIDTCLAVADVAGVQVALHSDTLNETGFVEDTIGAIAGRSIHAYHTEGAGGGH APDIITVAAQPNVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLNPRIPEDLAFAESRIRPSTIAAEDVLHDMGAISMIGSD SQAMGRVGEVVLRTWQTAHVMKARRGALEGDPSGSQAADNNRVRRYIAKYTICPAIAHGMDHLIGSVEVGKLADLVLWEP AFFGVRPHVVLKGGAIAWAAMGDANASIPTPQPVLPRPMFGAAAATAAATSVHFVAPQSIDARLADRLAVNRGLAPVADV RAVGKTDLPLNDALPSIEVDPDTFTVRIDGQVWQPQPAAELPMTQRYFLF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ureC | NP_286680.1 | urease subunit alpha | Virulence | TAI | Protein | 3e-137 | 63 |
| ureC | NP_287088.1 | urease subunit alpha | Not tested | TAI | Protein | 3e-137 | 63 |
| ureC | YP_005684266.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 2e-139 | 59 |
| ureC | YP_005682174.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 2e-139 | 59 |
| ureC | YP_003784325.1 | urease subunit alpha | Not tested | PiCp 7 | Protein | 2e-139 | 59 |
| ureC | YP_005686358.1 | Urease alpha subunit | Not tested | PiCp 7 | Protein | 2e-139 | 59 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ureC | YP_005923082.1 | urease subunit alpha | VFG0270 | Protein | 1e-120 | 55 |
