Gene Information

Name : lysS (MTCTRI2_1669)
Accession : YP_005916713.1
Strain : Mycobacterium tuberculosis CTRI-2
Genome accession: NC_017524
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1839768 - 1843286 bp
Length : 3519 bp
Strand : -
Note : Mapped to H37Rv Rv1640c

DNA sequence :
GTGGGACTCCACTTAACTGTCCCTGGCCTTCGCCGGGATGGTCGCGGCGTCCAGTCTAACAGCCATGACACGTCATCTAA
GACAACGGCCGACATCAGCCGGTGCCCTCAGCACACCGATGCGGGGCTACAAAGGGCTGCAACGCCGGGCATTTCCCGGC
TTTTGGGAATATCCTCGCGGTCTGTGACACTCACCAAACCTCGCTCGGCCACCAGGGGAAACTCCCGGTATCACTGGGTT
CCCGCGGCAGCCGGCTGGACCGTCGGCGTGATCGCGACCCTGTCACTACTGGCCAGTGTGTCGCCGTTGATTCGGTGGAT
CATCAAGGTTCCGCGCGAATTCATCAACGATTATCTGTTCAACTTCCCCGACACCAACTTCGCGTGGTCCTTCGTGCTGG
CATTGCTGGCCGCCGCGTTAACGGCACGCAAACGCATTGCCTGGTTGGTCTTGCTGGCAAATATGGTCCTGGCCGCCGTG
GTCAACGCCGCCGAGATCGCAGCGGGCGGCAACACCGCCGCCGAGAGCTTCGGGGAGAATCTCGGATTCGCCGTGCATGT
TGTGGCAATCGTCGTTCTGGTGCTGGGCTATCGGGAGTTCTGGGCCAAGGTCCGCAGGGGCGCGCTGTTTCGGGCGGCTG
CGGTGTGGCTTGCCGGCGCGGTGGTCGGAATCGTGGCGTCTTGGGGTCTGGTCGAACTGTTTCCGGGATCACTAGCGCCG
GACGAGCGGTTGGGTTACGCGGCCAACCGGGTGGTCGGATTCGCCCTCGCCGATCCCGATCTGTTCACCGGCAGACCGCA
CGTCTTCCTCAACGCGATCTTCGGGTTGTTCGGCGCGTTCGCGTTGATCGGGGCTGCGATCGTCTTGTTCCTATCTCAGC
GCGCTGACAATGCGCTGACCGGAGAGGACGAATCCGCTATCCGCGGGTTATTGGATTTGTATGGGAAGGACGACTCACTG
GGCTACTTCGCCACCCGTCGCGACAAGTCGGTGGTATTCGCATCCAGCGGCCGCGCCTGTATCACCTACCGTGTCGAGGT
CGGTGTCTGCCTAGCCAGCGGCGACCCGGTAGGCGACCACAGAGCATGGCCGCAGGCCGTCGACGCGTGGCTGCGGCTGT
GCCAGACCTACGGCTGGGCACCCGGCGTGATGGGCGCCAGTTCACAAGGGGCTCAGACATATCGCGAAGCGGGCCTAACC
GCGCTCGAGCTGGGCGATGAGGCCATCCTGCGGCCAGCCGATTTCAAGTTGTCCGGCCCGGAGATGCGCGGGGTGCGCCA
GGCCGTGACGCGGGCCCGGCGGGCGGGGTTGACGGTGCGCATCCGGCGGCATCGCGACATTGCCGAAGACGAGATGGCGC
AGACCATCACACGGGCGGATTCCTGGCGCGACACCGAGACCGAGCGCGGCTTCTCGATGGCGCTGGGCCGCCTCGGCGAC
CCCGCGGACTCCGACTGCCTGCTGGTGGAGGCGATTGATCCGCACAACCAGGTGCTGGCAATGCTGTCGCTGGTGCCGTG
GGGAACCACCGGTGTCTCCCTGGATTTGATGCGTCGTTCTCCACAATCCCCGAACGGCACTATCGAACTTATGGTCAGCG
AACTCGCCTTGCACGCTGAAAGCCTTGGTATCACTCGTATTTCGTTGAACTTCGCGGTGTTTCGCGCGGCCTTCGAGCAG
GGCGCCCAACTCGGCGCCGGCCCGGTTGCCCGGTTGTGGCGGGGGCTGCTGGTCTTCTTCTCACGGTGGTGGCAGCTCGA
GACGCTCTACCGCTCCAACATGAAGTACCAACCCGAATGGGTACCGCGCTACGCCTGCTACGAAGACGCCCGAGTGATTC
CCCGAGTGGGCGTCGCCTCGGTGATCGCAGAGGGGTTCCTCGTGCTGCCGTTCAGCCGGCGCAACCGAGTACACACGGGG
CATCATCCGGCAGTGCCCGAGCGGTTGGCGGCCACCGGCCTATTGCATCACGACGGCTCGGCACCGGACGTGAGCGGGCT
GCGGCAAGTAGGCCTCACCAATGGCGACGGGGTCGAGCGGCGGCTACCCGAGCAGGTGCGAGTTCGGTTCGACAAGCTAG
AGAAGCTGCGGAGCAGCGGCATTGACGCCTTTCCCGTGGGCCGGCCGCCCAGTCACACGGTGGCACAGGCGCTGGCCGCA
GACCACCAGGCTAGCGTGTCGGTGTCCGGACGCATCATGCGAATACGTAACTACGGTGGTGTGTTGTTCGCCCAGCTGCG
CGACTGGTCGGGCGAAATGCAAGTGCTGCTGGATAATTCACGCCTGGACCAGGGCTGCGCGGCCGACTTCAACGCGGCGA
CCGATCTGGGTGATCTGGTGGAGATGACCGGACACATGGGCGCCAGCAAGACCGGAACTCCATCGTTGATCGTCAGCGGC
TGGCGCCTGATCGGTAAGTGTTTGCGACCGTTGCCGAATAAGTGGAAGGGGCTACTGGATCCCGAAGCCCGAGTCCGGAC
CCGTTACCTCGACCTGGCGGTCAACGCTGAGTCCCGTGCGCTGATCACCGCTCGCAGCAGCGTGCTGCGCGCTGTGCGCG
AGACGCTGTTCGCAAAGGGATTCGTCGAGGTCGAAACGCCGATCCTACAGCAGCTGCACGGCGGCGCCACCGCCCGACCG
TTCGTCACGCACATCAACACGTATTCCATGGATCTGTTCCTGCGCATCGCACCAGAGCTCTACCTCAAGCGCCTGTGCGT
CGGCGGCGTGGAACGGGTATTCGAGCTCGGCCGTGCCTTTCGCAACGAGGGCGTCGACTTCAGCCACAACCCGGAGTTCA
CCCTACTGGAGGCCTATCAAGCACACGCCGACTACCTTGAGTGGATTGACGGCTGCCGCGAACTCATCCAGAACGCCGCC
CAGGCCGCCAACGGGGCGCCCATCGCCATGCGGCCCCGGACGGACAAGGGTTCCGACGGCACCCGCCACCACCTCGAACC
GGTCGACATCTCCGGGATATGGCCGGTGCGGACGGTGCATGATGCGATCTCGGAAGCACTCGGTGAACGCATCGACGCCG
ATACCGGCTTGACCACTCTCCGCAAGCTGTGCGACGCCGCCGGTGTCCCCTATCGGACCCAATGGGATGCCGGCGCGGTC
GTGCTCGAGCTATACGAGCACCTGGTGGAGTGCCGCACCGAGCAACCGACGTTCTACATCGACTTTCCGACATCGGTGTC
ACCGTTGACCCGACCGCATCGCAGCAAGCGCGGTGTCGCCGAGCGTTGGGACCTGGTGGCGTGGGGTATCGAGCTGGGCA
CCGCCTACAGCGAGCTGACCGACCCGGTGGAGCAACGGCGCCGCCTGCAGGAGCAGTCCCTGCTGGCCGCCGGCGGAGAC
CCCGAGGCGATGGAACTCGACGAAGACTTCCTGCAAGCGATGGAGTACGCCATGCCGCCCACCGGCGGCTTGGGCATGGG
CATTGACCGGGTGGTCATGCTGATCACTGGGCGCAGCATTCGCGAAACACTGCCCTTTCCGTTGGCAAAACCGCATTAG

Protein sequence :
MGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYHWV
PAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLAAV
VNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSLAP
DERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDDSL
GYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAGLT
ALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRLGD
PADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAFEQ
GAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVHTG
HHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQALAA
DHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASKTGTPSLIVSG
WRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARP
FVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLEWIDGCRELIQNAA
QAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAGAV
VLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAGGD
PEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 1e-155 43
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 1e-155 43
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 3e-155 43
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 1e-155 43