Gene Information

Name : CCDC5079_0997 (CCDC5079_0997)
Accession : YP_005912420.1
Strain : Mycobacterium tuberculosis CCDC5079
Genome accession: NC_017523
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1200298 - 1201464 bp
Length : 1167 bp
Strand : +
Note : -

DNA sequence :
ATGAGCGAAGACCGCACGGGACACCAGGGAATCAGCGGACCGGCCACCCGCGCCATCCACGCTGGCTACCGCCCGGATCC
GGCGACCGGGGCGGTGAACGTGCCGATCTACGCCAGCAGCACCTTCGCCCAAGACGGCGTCGGCGGTCTGCGTGGCGGTT
TCGAATACGCACGCACCGGCAACCCCACCCGGGCCGCATTGGAGGCCTCGCTGGCGGCAGTCGAGGAGGGTGCTTTCGCG
CGGGCATTCAGTTCCGGGATGGCCGCGACCGACTGCGCCCTGCGGGCGATGTTACGGCCCGGAGACCACGTCGTCATTCC
CGATGACGCCTACGGCGGCACATTCCGGTTGATAGACAAGGTGTTCACCCGGTGGGATGTCCAGTACACGCCGGTGCGGC
TTGCCGATCTGGATGCGGTGGGTGCCGCGATTACTCCGCGCACCCGGCTGATTTGGGTGGAGACGCCCACCAATCCGCTA
CTGTCGATCGCCGATATCACGGCCATTGCCGAGCTGGGCACAGACAGATCGGCAAAAGTATTGGTGGACAATACCTTTGC
CTCACCCGCGTTGCAGCAGCCGTTGCGGCTGGGCGCCGATGTGGTGTTGCACTCGACTACCAAGTACATCGGCGGCCATT
CCGACGTGGTGGGAGGTGCGCTGGTCACCAACGACGAAGAGCTGGACGAGGAGTTCGCTTTCTTGCAGAACGGCGCCGGC
GCGGTGCCCGGACCATTCGACGCCTACCTGACCATGCGCGGCCTGAAGACCTTGGTGCTGCGGATGCAGCGGCACAGTGA
AAATGCCTGTGCGGTAGCGGAATTCCTCGCTGATCATCCGTCGGTGAGTTCTGTGTTGTATCCGGGTTTGCCCAGTCATC
CCGGGCATGAGATTGCCGCGCGACAGATGCGCGGCTTCGGCGGCATGGTTTCGGTGCGGATGCGGGCCGGTCGGCGTGCG
GCGCAGGACCTGTGTGCCAAGACCCGCGTCTTCATCCTGGCCGAGTCGCTGGGTGGGGTGGAGTCGCTGATCGAACATCC
CAGCGCCATGACCCATGCGTCGACGGCCGGTTCGCAATTGGAGGTGCCCGACGATCTGGTGCGGCTTTCGGTCGGTATCG
AAGACATTGCCGACCTGCTCGGCGATCTCGAACAGGCCCTGGGTTAA

Protein sequence :
MSEDRTGHQGISGPATRAIHAGYRPDPATGAVNVPIYASSTFAQDGVGGLRGGFEYARTGNPTRAALEASLAAVEEGAFA
RAFSSGMAATDCALRAMLRPGDHVVIPDDAYGGTFRLIDKVFTRWDVQYTPVRLADLDAVGAAITPRTRLIWVETPTNPL
LSIADITAIAELGTDRSAKVLVDNTFASPALQQPLRLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDEEFAFLQNGAG
AVPGPFDAYLTMRGLKTLVLRMQRHSENACAVAEFLADHPSVSSVLYPGLPSHPGHEIAARQMRGFGGMVSVRMRAGRRA
AQDLCAKTRVFILAESLGGVESLIEHPSAMTHASTAGSQLEVPDDLVRLSVGIEDIADLLGDLEQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-71 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-72 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-56 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CCDC5079_0997 YP_005912420.1 cystathionine gamma-synthase BAC0207 Protein 1e-60 43