Gene Information

Name : CCDC5180_0355 (CCDC5180_0355)
Accession : YP_005908187.1
Strain : Mycobacterium tuberculosis CCDC5180
Genome accession: NC_017522
Putative virulence/resistance : Virulence
Product : endopeptidase subunit ATP binding protein B clpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 455267 - 457900 bp
Length : 2634 bp
Strand : -
Note : -

DNA sequence :
GTGGGTAAAATTGAGCGGAACAGACTCAACATTGACGGCGTTGAACAACCCGACAAGCATTTCGAACGGACCCCGAATGG
AGGTGTCGTGGACTCGTTTAACCCGACGACCAAGACGCAGGCGGCGCTAACCGCGGCGTTACAGGCGGCTTCGACCGCCG
GCAATCCCGAGATCCGGCCCGCTCACCTGCTGATGGCGCTGCTGACCCAAAACGACGGTATCGCCGCACCGCTACTGGAG
GCTGTCGGTGTCGAGCCCGCCACCGTCCGCGCCGAAACCCAGCGCCTGCTCGACCGTTTGCCGCAGGCGACTGGAGCCAG
CACGCAGCCGCAGCTGTCCCGCGAGTCGTTAGCGGCGATCACCACCGCGCAGCAGCTGGCCACCGAGCTGGACGACGAGT
ACGTCTCCACCGAGCACGTGATGGTCGGGCTGGCCACCGGTGACTCCGACGTCGCCAAGCTGTTGACCGGCCACGGCGCC
TCGCCGCAGGCGCTGCGGGAGGCGTTCGTCAAGGTGCGCGGCAGCGCCCGGGTCACCAGCCCCGAACCGGAGGCGACCTA
TCAGGCGCTGCAGAAGTACTCCACCGACCTGACCGCCCGCGCCCGCGAAGGCAAACTCGACCCGGTCATCGGCCGCGACA
ACGAGATCCGCCGCGTGGTGCAGGTGCTGTCCCGTCGCACCAAGAACAACCCGGTGCTGATCGGTGAGCCCGGCGTCGGC
AAGACCGCGATCGTGGAGGGCCTGGCGCAGCGCATCGTGGCCGGCGACGTGCCGGAGAGCTTGCGCGACAAGACCATCGT
CGCGCTCGATCTCGGCTCGATGGTCGCCGGCTCCAAATACCGCGGCGAATTCGAGGAACGGCTCAAGGCCGTCCTCGACG
ACATCAAGAACTCGGCCGGCCAAATCATCACGTTCATCGACGAGCTGCACACCATCGTCGGCGCCGGCGCCACCGGCGAG
GGGGCGATGGACGCCGGCAACATGATCAAGCCGATGCTGGCCCGCGGCGAGTTACGGCTGGTCGGGGCGACCACGCTGGA
CGAATACCGCAAGCACATCGAGAAGGACGCCGCGCTCGAGCGCCGTTTCCAACAGGTGTACGTCGGCGAGCCGTCGGTGG
AGGACACCATCGGCATCCTGCGCGGGCTCAAAGACCGCTACGAGGTGCACCACGGGGTGCGCATCACCGACTCGGCGCTG
GTGGCAGCTGCCACTTTGAGCGACCGGTATATCACCGCCCGCTTCCTGCCCGACAAGGCCATCGACCTGGTCGACGAGGC
GGCCAGCCGGCTGCGGATGGAGATCGACTCGCGGCCCGTCGAGATCGACGAGGTCGAGCGGCTGGTGCGCCGGCTGGAGA
TCGAAGAGATGGCGCTGTCCAAAGAAGAAGACGAGGCGTCGGCGGAGCGGTTGGCCAAGCTGCGCTCCGAGCTGGCCGAC
CAGAAAGAGAAGTTGGCCGAGCTCACCACCCGCTGGCAGAACGAGAAGAACGCGATCGAAATCGTCCGCGACCTCAAGGA
GCAGCTGGAAGCCCTGCGCGGGGAATCCGAGCGGGCCGAACGCGACGGCGACCTGGCCAAGGCCGCCGAGCTGCGCTACG
GACGCATCCCCGAGGTGGAGAAGAAGCTCGACGCGGCGTTGCCGCAGGCGCAGGCCCGGGAGCAGGTGATGCTCAAAGAG
GAGGTCGGTCCCGACGACATCGCCGACGTGGTGTCGGCGTGGACCGGCATCCCGGCCGGTCGGCTGCTGGAAGGCGAGAC
CGCCAAGCTGCTGCGCATGGAAGACGAGCTGGGCAAGCGGGTCATCGGGCAGAAGGCCGCGGTTACCGCAGTCTCTGATG
CGGTGCGGCGCAGCCGGGCCGGGGTGTCCGACCCCAACCGGCCCACCGGGGCGTTCATGTTCCTCGGCCCGACCGGTGTC
GGCAAGACCGAGCTGGCCAAGGCGCTGGCCGACTTCCTGTTCGACGACGAGCGGGCGATGGTCCGCATCGACATGAGCGA
GTACGGCGAGAAGCACACCGTGGCTCGGTTGATCGGCGCCCCGCCCGGCTATGTGGGATACGAGGCGGGCGGTCAGCTGA
CCGAGGCGGTGCGCCGGCGTCCCTACACGGTGGTGCTGTTCGACGAGATCGAGAAGGCGCACCCGGACGTGTTCGACGTG
CTGCTGCAGGTCCTCGACGAGGGCCGGCTCACCGACGGGCACGGCCGCACGGTCGACTTCCGCAACACCATCTTGATCCT
GACGTCCAACCTGGGGTCGGGTGGCAGCGCCGAGCAGGTGCTGGCCGCGGTGCGCGCTACGTTCAAGCCGGAGTTCATCA
ACCGGCTCGACGACGTGCTCATCTTTGAGGGTCTCAACCCCGAAGAGCTGGTGCGCATCGTCGACATCCAGCTGGCGCAG
CTGGGCAAGCGGCTGGCGCAGCGGCGGCTGCAGCTGCAGGTCTCGCTGCCGGCCAAGCGCTGGTTGGCGCAGCGCGGATT
CGACCCGGTGTACGGGGCGCGGCCGTTGCGCCGGCTGGTGCAGCAGGCCATCGGTGACCAGCTGGCCAAGATGCTGTTGG
CCGGCCAGGTGCACGACGGCGATACCGTGCCGGTCAACGTCAGCCCCGACGCCGACTCGCTGATCCTGGGCTGA

Protein sequence :
MGKIERNRLNIDGVEQPDKHFERTPNGGVVDSFNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDGIAAPLLE
AVGVEPATVRAETQRLLDRLPQATGASTQPQLSRESLAAITTAQQLATELDDEYVSTEHVMVGLATGDSDVAKLLTGHGA
SPQALREAFVKVRGSARVTSPEPEATYQALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEPGVG
KTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGE
GAMDAGNMIKPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSVEDTIGILRGLKDRYEVHHGVRITDSAL
VAAATLSDRYITARFLPDKAIDLVDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASAERLAKLRSELAD
QKEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAERDGDLAKAAELRYGRIPEVEKKLDAALPQAQAREQVMLKE
EVGPDDIADVVSAWTGIPAGRLLEGETAKLLRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVSDPNRPTGAFMFLGPTGV
GKTELAKALADFLFDDERAMVRIDMSEYGEKHTVARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDV
LLQVLDEGRLTDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFKPEFINRLDDVLIFEGLNPEELVRIVDIQLAQ
LGKRLAQRRLQLQVSLPAKRWLAQRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPDADSLILG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 7e-105 43
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 2e-105 42
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-105 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CCDC5180_0355 YP_005908187.1 endopeptidase subunit ATP binding protein B clpB VFG2076 Protein 4e-112 44
CCDC5180_0355 YP_005908187.1 endopeptidase subunit ATP binding protein B clpB VFG2084 Protein 8e-112 41