Gene Information

Name : pyk (NMBNZ0533_0095)
Accession : YP_005902757.1
Strain : Neisseria meningitidis NZ-05/33
Genome accession: NC_017518
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 102139 - 103611 bp
Length : 1473 bp
Strand : -
Note : -

DNA sequence :
ATGAACCAGACAAGCCGCGATCTGACCCGCATCAGCCACAACACCAAAATCGTCGCCACCTTGGGGCCGGGCAGCAACAA
CGTCGAACTGTTGGAAGACATGATCCGCGTCGGCGGTCTGAACGTCGTCCGCTTCAACTTCAGCCACGGCACGCCCGAAT
TCCATCAGGAAAACGCCCGCATTGTGCGCGAGGCGGCAAAACGCGCCGGACAGGAAATCGCCATCATTGCCGACCTGCAA
GGGCCGAAAATCCGCGTGGGCAAAATCGCCGGCGGCGGCATCGAATTGAACAAAGGCGAAACGCTGGTACTGGATGCCGC
GCTCGAAGGCGAAGGCACGCGCGAGGCGGTCGGTTTGGACTACCGCGACCTGCCCGACGACGTTACCGCAGGCGACGTAT
TGTGGCTGGACGACGGCCTGCTGACCCTGACCGTGGAATCCGTCGAAGGCAGCAGGATTATCACAAGGGTGGAAAACAGC
CATGTCCTGAAAAGCAACAAAGGCATCAACAAACGCGGCGGCGGGCTGTCCGCAGGCGCGTTGACCGAAAAAGACTTCCG
CGACCTGAAAACCGCGATTGCCATCGGTTGCGACTACCTCGCCATCAGCTTTGTGAAATCTGCCGAAGATTTGCACATCG
CGCGCGCCAAAGTCGAAGAAGAAATGAAGGGCAGCACTGCCGTGCGCCCCGGTTTGGTTTCCAAAATCGAACGCGTAGAA
GCGATTGAAAACCTTGATGAAATCATCCTCGCCGGCGACGGCATTATGGTTGCGCGCGGCGACTTGGCGGTCGAAGTCGG
ACACGCCGCCGTCCCCGCCCTGCAAAAACGGATGATCCGCCGCGCCCGCGAGTTGCGCCGCTTCAGCATTACGGCGACGC
AAATGATGGAATCGATGATTACCAACCCCGTGCCGACCCGCGCGGAAGTCAGCGATGTGGCAAACGCGGTATTGGACGGT
ACCGATGCGGTGATGTGTTCCGCCGAAACCGCCGTCGGCGCGTATCCGTTTGAAACCGTCAGCCAAATGGCAATTATCTG
CGCGGCTGCGGAAAAAGAGCAGGATTCGCTCAACGGCGTTGCCGAACAGGCGGAGTATCCCGAAGCGGTCAGCACCAACC
TAGCGGTTGCCGGCGGCGCGGTCAGCGTGGCGCGCGCGGTTCACGCCAAAGCGATTGTCGCCCTGACCGAAAGCGGTTCG
ACCGCCTTTGAAATCAGCCGCCACAACATCACCCTGCCGATTTTCGCGCTGACCCCGAGCGTTTCCGCCCAACGCCGTAT
GGCGATGTACCGCGGCGTGCGCCCGCTGATTTTGGCAACCAGTACCGACCACGACACGGCGTTGAACGAAGTCGAAACCA
TGCTGGTGGAACACAACATCCTGCATTCCGGCGACCAATACATCATCACCAGCGGCTCGCAAATGCGCGAATCCGGTTCG
ACCAATACGCTGGAAGTGCTGCGCGTCAAATAA

Protein sequence :
MNQTSRDLTRISHNTKIVATLGPGSNNVELLEDMIRVGGLNVVRFNFSHGTPEFHQENARIVREAAKRAGQEIAIIADLQ
GPKIRVGKIAGGGIELNKGETLVLDAALEGEGTREAVGLDYRDLPDDVTAGDVLWLDDGLLTLTVESVEGSRIITRVENS
HVLKSNKGINKRGGGLSAGALTEKDFRDLKTAIAIGCDYLAISFVKSAEDLHIARAKVEEEMKGSTAVRPGLVSKIERVE
AIENLDEIILAGDGIMVARGDLAVEVGHAAVPALQKRMIRRARELRRFSITATQMMESMITNPVPTRAEVSDVANAVLDG
TDAVMCSAETAVGAYPFETVSQMAIICAAAEKEQDSLNGVAEQAEYPEAVSTNLAVAGGAVSVARAVHAKAIVALTESGS
TAFEISRHNITLPIFALTPSVSAQRRMAMYRGVRPLILATSTDHDTALNEVETMLVEHNILHSGDQYIITSGSQMRESGS
TNTLEVLRVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 0.0 99
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-53 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-53 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-53 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-53 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_005902757.1 pyruvate kinase VFG0479 Protein 1e-53 42