Gene Information

Name : NMBH4476_0082 (NMBH4476_0082)
Accession : YP_005898815.1
Strain : Neisseria meningitidis H44/76
Genome accession: NC_017516
Putative virulence/resistance : Virulence
Product : capsule polysaccharide modification protein LipA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 91378 - 93492 bp
Length : 2115 bp
Strand : +
Note : -

DNA sequence :
ATGTTCCTCTTTTCAGACGGCCTACAATCCATTAATAACAATAATCGACGAAAACGCATTGTGAAAAACGCCTACATCCC
CTCTCGCGGCATCCGCAAAATCCCCCATCTCTCCACCCTATTGCCTGAATTTCATATCTGCAAAGACGGGAAAGAAGCAG
AGGCTGTTGTCGGCTGGGGTTTGCGCCCGACGACACACAAAGCGCGTGCTTTTGCCGCTGAACACCAGCTTCCCTTTATT
GCTTTGGAAGACGGCTTTTTACGATCGCTCGGACTGGGTGTCGCCGGTTATCCGCCCTACTCTATCGTCTATGACGACAT
CGGCATCTACTACGACACCACACGTCCTTCGCGTTTGGAACAACTGATTCTTGCCGCCGATACCATGCCGTCTGAAACCT
TGGCTCAGGCGCAGCAGGCGATGGATTTCATCCTGCAACACCACCTGTCCAAATACAACCACGCGCCCGAACTTTCAGAC
GACCATCCTTTACGTTCCCCATCCAAACCCGAAACCGTCCTCATCATCGACCAAACCTTCGGCGATATGGCCATCCAATA
TGGCGGCGCAGACGCCTCTACGTTTGAACTGATGTTTCAGACGGCCTTAAATGAAAACCCGCAAGCCGATATCTGGGTAA
AAACCCATCCCGATGTTTTGTGCGGCAAAAAACAAGGCTATCTGACCCAACTGGCGCAGCAACACCGCGTCCATCTTTTG
GCAGAAGACATCAATCCGATTTCTTTGTTGCAAAACGTTGATAAAGTTTATTGCGTTACCTCGCAAATGGGTTTTGAGGC
GCTTTTGTGCGGCAAACCGCTGACCACTTTCGGCCTGCCGTGGTATGCCGGATGGGGTGTAAGCGACGACCGCCATCCTG
AAATCAACCGCCTTGTTCAAACCCAACGCCGCGCCACCCGCAACTTGCTGCAGCTCTTCGCCGCAGCCTATCTGCAATAC
AGCCGCTACCTCAACCCCAATACCGGCGAAGCAGGCAGCCTCTTTGATGTCATCGACTATCTGGCGACGGTCAAACGTAA
AAACGACAAATTGCGTGGCGAGTTATATTGCGTCGGTATGTCTTTGTGGAAACGCGCGGTTGCCAAACCGTTCTTTAACG
TACCCTCTTGCCGTCTGAAATTTATCTCTTCCACCCAAAAACTGGCAAGGGTCAAACTGTCCGACGATGCACGCATCCTG
GCTTGGGGCAACGGCAAAGAGGCCATCGTCCGCTTTGCCGAACAACACCACATCCCCCTGCTGCGCATGGAAGACGGCTT
TATCCGCTCGGTCGGACTCGGCTCCAACTTAGTGCCGCCGCTGTCGCTCGTTACCGACGATATGAGCATTTATTTCAATG
CCGAAACCCCGTCCCGTCTTGAATACATCCTACAAAACCAAAACTTCGACGATCAAGACTTTCAGACGGCCTTGAAGCTG
CAAAAAATGCTGACCGAAAACCACATCAGTAAATACAACGTCGGCAGCTCAGACTTCACCGCCCCGTCAACCGACAAAAC
CGTGATCCTCGTTCCCGGCCAGGTTGAAGATGATGCGTCTATCCGCTACGGTTCGCCCCAAATCTACCGCAATCTGGATT
TGCTCCGTACCGTACGCGAACGAAACCCCAATGCCTATATCATCTACAAACCGCATCCCGATGTAGTCAGCGGTAACCGC
ATCGGCCATATTTCCCCTGAAGATGCTGCACGATATGCCGACCAAACCGCCGAACAAGCCGACATCCTGACCTGTCTCCA
ATACGCAGACGAAATACATACCATGACTTCGCTGACCGGTTTTGAAGCCTTGTTGCGCGGCAAAAAAGTCAGCTGCTACG
GCCTGCCTTTTTACGCAGGCTGGGGGCTTACCCAAGATCTGCTCCCCATCCCGCGCCGTAGCCGCAGACTTGAGCTTTGG
CAGCTGATTGCCGGCACGCTCATCCACTATCCCGACTACATCCACCCCGAAACCCATCAGGCCATAAATGCAGAAACCGC
AGCCCAAATCCTGATACGACAAAAAAATATGCAAAAAAACAACAACGGATTACATCGCGGGTGCTTTGCCAAAAAATTAG
GTAAAATCAAACAACTATATCGATCTTTCAAATAA

Protein sequence :
MFLFSDGLQSINNNNRRKRIVKNAYIPSRGIRKIPHLSTLLPEFHICKDGKEAEAVVGWGLRPTTHKARAFAAEHQLPFI
ALEDGFLRSLGLGVAGYPPYSIVYDDIGIYYDTTRPSRLEQLILAADTMPSETLAQAQQAMDFILQHHLSKYNHAPELSD
DHPLRSPSKPETVLIIDQTFGDMAIQYGGADASTFELMFQTALNENPQADIWVKTHPDVLCGKKQGYLTQLAQQHRVHLL
AEDINPISLLQNVDKVYCVTSQMGFEALLCGKPLTTFGLPWYAGWGVSDDRHPEINRLVQTQRRATRNLLQLFAAAYLQY
SRYLNPNTGEAGSLFDVIDYLATVKRKNDKLRGELYCVGMSLWKRAVAKPFFNVPSCRLKFISSTQKLARVKLSDDARIL
AWGNGKEAIVRFAEQHHIPLLRMEDGFIRSVGLGSNLVPPLSLVTDDMSIYFNAETPSRLEYILQNQNFDDQDFQTALKL
QKMLTENHISKYNVGSSDFTAPSTDKTVILVPGQVEDDASIRYGSPQIYRNLDLLRTVRERNPNAYIIYKPHPDVVSGNR
IGHISPEDAARYADQTAEQADILTCLQYADEIHTMTSLTGFEALLRGKKVSCYGLPFYAGWGLTQDLLPIPRRSRRLELW
QLIAGTLIHYPDYIHPETHQAINAETAAQILIRQKNMQKNNNGLHRGCFAKKLGKIKQLYRSFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 0.0 100
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 7e-134 50
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 5e-134 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NMBH4476_0082 YP_005898815.1 capsule polysaccharide modification protein LipA VFG0259 Protein 0.0 100
NMBH4476_0082 YP_005898815.1 capsule polysaccharide modification protein LipA VFG0704 Protein 6e-157 58
NMBH4476_0082 YP_005898815.1 capsule polysaccharide modification protein LipA VFG0692 Protein 9e-180 58