Gene Information

Name : NMBG2136_0083 (NMBG2136_0083)
Accession : YP_005893009.1
Strain : Neisseria meningitidis G2136
Genome accession: NC_017513
Putative virulence/resistance : Virulence
Product : capsule polysaccharide modification protein LipA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 87866 - 89980 bp
Length : 2115 bp
Strand : +
Note : -

DNA sequence :
ATGTTCCTCTTTTCAGACGGCCTACAATCTATTAATAACAATAATCGACGAAAACGCATTGTGAAAAACGCCTACATCCC
CTCTCGCGGCATCCGCAAAATCCCCCATCTCTCCACCCTATTGCCCGAGTTTCATATCTACAAAGACGGAAAAGGAGCAG
AGGCTGTTATCGGCTGGGGTTTGCGCCCGACGACACACAAAGCGCGTGCTTTTGCCGCTGAACACCAGCTTCCCTTTATT
GCTTTGGAAGACGGCTTTTTACGCTCGCTTGGCCTGGGCGTTGCCGGCTATCCTCCCTATTCCATCGTCTATGACGACAT
CGGCATCTACTACGACACTACCCGCCCTTCTCGTTTGGAACAACTGATTCTTGCCGCCGATACCATGCCGTCTGAAACCT
TGGCTCAGGCGCAACAGACGATGGATTTCATCCTGCAACACCACCTGTCCAAATACAACCACGCGCCCGAACTTTCAGAC
GATCATCCTTTACGCTCCCCATCCAAGCCTGAAACCGTCCTCATCATCGACCAAACCTTCGGCGATATGGCCATCCAATA
TGGCGGCGCAGACGCCTCTACGTTTGAACTGATGTTTCAGACGGCCTTAAATGAAAACCCGCAAGCCGATATTTGGGTCA
AAACCCACCCCGATGTTTTGTGCGGCAAAAAACAAGGCTATCTGACCCAGCTGGCGCAGCAACACCGCGTCCATCTTTTA
GCAGAAGACATCAACCCGATTTCTTTGTTGCAAAACGTCGATAAAGTTTATTGCGTTACCTCGCAAATGGGTTTTGAGGC
ACTTTTGTGCGGCAAGCCGCTGACCACCTTCGGCCTGCCGTGGTATGCCGGATGGGGTGTAAGCGACGACCGCCATCCTG
AAATCAACCGCCTTGTTCAAACCCAACGCCGCGCCACCCGCAACTTGCTGCAGCTCTTCGCCGCAGCCTATCTGCAATAC
AGCCGCTACCTCAACCCCAATACCGGCGAAGCAGGCAGCCTCTTTGATGTCATCGACTATCTGGCGACGGTCAAACGTAA
AAACGACAAATTGCGTGGCGAGTTATATTGCGTCGGTATGTCTTTGTGGAAACGCGCGGTTGCCAAACCGTTCTTTAACG
TACCCTCTTGCCGTCTGAAATTTATCTCTTCCACCCAAAAACTGGCAAGGGTCAAACTGTCCGACGATGCACGCATCCTG
GCTTGGGGCAACGGCAAAGAGGCCATCGTCCGCTTTGCCGAACAACACCACATCCCCCTGCTGCGCATGGAAGACGGCTT
TATCCGCTCGGTCGGACTCGGCTCCAACTTAGTGCCGCCGCTGTCGCTCGTTACCGACGATATGAGCATTTATTTCAATG
CCGAAACCCCGTCCCGTCTTGAATACATCCTACAAAACCAAAACTTCGACGATCAAGACTTTCAGACGGCCTTGAAGCTG
CAAAAAATGCTGACCGAAAACCACATCAGTAAATACAACGTCGGCAGCTCAGACTTCACCGCCCCGTCAACCGACAAAAC
CGTGATCCTCGTTCCCGGCCAGGTTGAAGATGATGCGTCTATCCGCTACGGTTCGCCCCAAATCTACCGCAATCTGGATT
TGCTCCGTACCGTACGCGAACGAAACCCCAATGCCTATATCATCTACAAACCGCATCCCGATGTAGTCAGCGGTAACCGC
ATCGGCCATATTTCCCCTGAAGATGCTGCACGATATGCCGACCAAACCGCCGAACAAGCCGACATCCTGACCTGTCTCCA
ATACGCAGACGAAATACATACCATGACTTCGCTGACCGGTTTTGAAGCCTTGTTGCGCGGCAAAAAAGTCAGCTGCTACG
GCCTGCCTTTTTACGCAGGCTGGGGGCTTACCCAAGATCTGCTCCCCATCCCGCGCCGTAGCCGCAGACTTGAGCTTTGG
CAGCTGATTGCCGGCACGCTCATCCACTATCCCGACTACATCCACCCCGAAACCCATCAGGCCATAAATGCAGAAACCGC
AGCCCAAATCCTGATACGACAAAAAAATATGCAAAAAAACAACAACGGATTACATCGCGGGTGCTTTGCCAAAAAATTAG
GTAAAATCAAACAACTATATCGATCTTTCAAATAA

Protein sequence :
MFLFSDGLQSINNNNRRKRIVKNAYIPSRGIRKIPHLSTLLPEFHIYKDGKGAEAVIGWGLRPTTHKARAFAAEHQLPFI
ALEDGFLRSLGLGVAGYPPYSIVYDDIGIYYDTTRPSRLEQLILAADTMPSETLAQAQQTMDFILQHHLSKYNHAPELSD
DHPLRSPSKPETVLIIDQTFGDMAIQYGGADASTFELMFQTALNENPQADIWVKTHPDVLCGKKQGYLTQLAQQHRVHLL
AEDINPISLLQNVDKVYCVTSQMGFEALLCGKPLTTFGLPWYAGWGVSDDRHPEINRLVQTQRRATRNLLQLFAAAYLQY
SRYLNPNTGEAGSLFDVIDYLATVKRKNDKLRGELYCVGMSLWKRAVAKPFFNVPSCRLKFISSTQKLARVKLSDDARIL
AWGNGKEAIVRFAEQHHIPLLRMEDGFIRSVGLGSNLVPPLSLVTDDMSIYFNAETPSRLEYILQNQNFDDQDFQTALKL
QKMLTENHISKYNVGSSDFTAPSTDKTVILVPGQVEDDASIRYGSPQIYRNLDLLRTVRERNPNAYIIYKPHPDVVSGNR
IGHISPEDAARYADQTAEQADILTCLQYADEIHTMTSLTGFEALLRGKKVSCYGLPFYAGWGLTQDLLPIPRRSRRLELW
QLIAGTLIHYPDYIHPETHQAINAETAAQILIRQKNMQKNNNGLHRGCFAKKLGKIKQLYRSFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 0.0 99
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 4e-133 50
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 3e-133 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NMBG2136_0083 YP_005893009.1 capsule polysaccharide modification protein LipA VFG0259 Protein 0.0 99
NMBG2136_0083 YP_005893009.1 capsule polysaccharide modification protein LipA VFG0704 Protein 4e-157 58
NMBG2136_0083 YP_005893009.1 capsule polysaccharide modification protein LipA VFG0692 Protein 3e-180 58