Gene Information

Name : hemC (NMAA_0382)
Accession : YP_005891376.1
Strain : Neisseria meningitidis WUE 2594
Genome accession: NC_017512
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase (PBG; hydroxymethylbilane synthase; HMBS; pre-uroporphyrinogen synthase)
Function : -
COG functional category : -
COG ID : -
EC number : 2.5.1.61
Position : 478364 - 479299 bp
Length : 936 bp
Strand : +
Note : MultiFUN-ID: 1.5.3.12

DNA sequence : 
ATGAACCCGAAAAAACTCGTCATCGCCAGCCGCGAAAGCCTGCTTGCTATGTGGCAGGCAAAGCATATCCAAGGCCGTCT
GAAGGCTCTGTATCCCGATTGCGAAGTCGAGATTTTGGGCATGACCACGCGCGGCGATCAGATTTTGGACAAAACTTTGT
CAAAAGTCGGCGGTAAAGGCTTGTTTGTCAAAGAGTTGGAACAGGCTTTATATGACGGGCGCGCCGATTTGGCGGTGCAT
TCGATTAAAGACGTACCGATGGATTTGCCTGAAGGTTTCGCGCTTGCGGCCATCGGCGAACGCGCCAATCCGTTTGACGC
ATTTGTGTCCAACCAATACACGCGTTTGGAAGAAATGCCCGAAGGCGCGGTTGTCGGCACATCCAGCCTGCGCCGCGAAG
CCCAGTTGCGTGCGCGCTATCCGCATTTGCTTATCAAACCTTTGCGCGGCAATGTGCAAACCCGTTTGTCCAAACTCGAT
AACGGCGAATACGACGCAATTATCTTGGCTGCCGCCGGTTTGCAGCGTCTGAAATTGGACGGACGCATCCGCATGATTTT
GTCGGAATCCGACAGCCTGCCTGCCGCCGGACAAGGCGCATTGGGTATCGAAATTGCCGCGCACCGCGAAGATTTGTATG
AAGTTTTGAAACCCTTGAACCACGGTGTTACCAATGCCTGCGTTACCGCCGAACGCGCCCTCGCACGCGCTTTGGGCGGA
AGCTGCCAAGTGCCTTTGGCCGCATATTGCACGGAAGAAAACGGCTTGCTGACCTTGCGCGGCTTGGTCGGACACCCCGA
CGGTTCGGTTGTGTTGCGGGCGGACGCGCAAGCCCCTGCCGAATATGCCGACGCGCTCGGACGCGCTGTCGCTAAGAAAT
TGGCGGACGACGGTGCGCGGGAATTGATTGGAGCAGTATTGAATACGGAAAATTGA

Protein sequence : 
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDQILDKTLSKVGGKGLFVKELEQALYDGRADLAVH
SIKDVPMDLPEGFALAAIGERANPFDAFVSNQYTRLEEMPEGAVVGTSSLRREAQLRARYPHLLIKPLRGNVQTRLSKLD
NGEYDAIILAAAGLQRLKLDGRIRMILSESDSLPAAGQGALGIEIAAHREDLYEVLKPLNHGVTNACVTAERALARALGG
SCQVPLAAYCTEENGLLTLRGLVGHPDGSVVLRADAQAPAEYADALGRAVAKKLADDGARELIGAVLNTEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-70 56
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-70 56