Gene Information

Name : lipA (NMAA_1891)
Accession : YP_005892886.1
Strain : Neisseria meningitidis WUE 2594
Genome accession: NC_017512
Putative virulence/resistance : Virulence
Product : polysialic acid capsule modification protein LipA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2162476 - 2164590 bp
Length : 2115 bp
Strand : -
Note : -

DNA sequence : 
ATGTTCCTCTTTTCAGACGGCCTACAATCTATTAATAACAATAATCGACGAAAACGCATTGTGAAAAACGCCTACATCCC
CTCTCGCGGCATCCGCAAAATCCCCCATCTCTCCACCCTATTGCCCGAGTTTCATATCTACAAAGACGGAAAAGGAGCAG
AGGCTGTTGTCGGCTGGGGTTTGCGCCCGACGACACACAAAGCGCGTGCTTTTGCCACCGAACACCAGCTTCCCTTTATT
GCTTTGGAAGACGGCTTTTTACGCTCGCTCGGACTGGGCGTCTCCGGTTATCCCCCCTACTCCATCGTCTATGACGACAT
CGGCATCTACTACGACACTACCCGCCCTTCTCGTTTGGAACAACTGATTCTTGCCGCCGATACCATACCGTCTGAAACCT
TGGCTCAGGCGCGGCAGGCGATGGATTTCATCCTGCAACACCATCTGTCCAAATACAACCACGCGCCCGAACTTTCAGAC
GATCATCCTTTACGCTCCCCATCCAAGTCTGAAACCGTCCTCATTATCGACCAAACCTTCGGCGATATGGCTATCCAATA
TGGCGGTGCAGACGCCTCTACGTTTGAATTGATGTTTCAGACGGCCTTAAATGAAAACCCGCAAGCCGATATTTGGGTCA
AAACCCATCCCGATGTTTTGTGCGGCAAAAAACAAGGCTATCTGACCCAGCTTGTGCAGCAACACCGCGTCCATCTTCTG
GCAGAAGACATCAATCCGATTTCTTTGTTGCAAAACGTCGATAAAGTTTATTGCGTTACCTCGCAAATGGGTTTTGAGGC
GCTTTTGTGCGGCAAGCCGCTGACCACTTTCGGCCTGCCGTGGTATGCCGGATGGGGCGTGAGTGACGACCGCCACCCAA
AAATCGGCAGCCTTATTCAAACCCAACGCCGCGCCCCCCGCAACTTGCTGCAACTCTTCGCCGCAGCCTATCTGCAATAC
AGCCGCTACCTCAATCCCAATACCGGCGAAGCAGGCAGCCTCTTTGATGTCATCGACTATCTGGCGACGGTCAAACGTAA
AAACGACAAATTGCGTGGCGAGTTATATTGCGTCGGTATGTCTTTGTGGAAACGCGCGGTTGCCAAACCGTTCTTTAACG
TACCCTCTTGCCGTCTGAAATTTATCTCTTCCACCCAAAAACTGGCAAGGGTCAAACTGTCCGACGATGCACGCATCCTG
GCTTGGGGCAACGGCAAAGAGGCCATCGTCCGCTTTGCCGAACAACACCACATCCCCCTGCTGCGCATGGAAGACGGCTT
TATCCGCTCGGTCGGACTCGGCTCCAACTTAGTGCCGCCGCTGTCGCTCGTTACCGACGATATGAGCATTTATTTCAATG
CCGAAACCCCGTCCCGTCTTGAATACATCCTACAAAACCAAAACTTCGACGATCAAGACTTTCAGACGGCCTTGAAGCTG
CAAAAAATGCTGACCGAAAACCACATCAGTAAATACAACGTCGGCAGCTCAGACTTCACCGCCCCGTCAACCGACAAAAC
CGTGATCCTCGTTCCCGGCCAGGTTGAAGATGATGCGTCTATCCGCTACGGTTCGCCCCAAATCTACCGCAATCTGGATT
TGCTCCGTACCGTACGCGAACGAAACCCCAATGCCTATATCATCTACAAACCGCATCCCGATGTAGTCAGCGGTAACCGC
ATCGGCCATATTTCCCCTGATGATGCTGCACGATATGCCGACCAAACCGCCGAACAAGCCGACATCCTGACCTGTCTCCA
ATACGCAGACGAAATACATACCATGACTTCGCTGACCGGTTTTGAAGCCTTGTTGCGCGGCAAAAAAGTCAGCTGCTACG
GCCTGCCTTTCTATGCAGGTTGGGGGCTTACCCAAGATCTGCTCCCTATTCCGCGCCGCAGCCGCAGGCTTGAGCTTTGG
CAGCTGGTTGCCGGCACGCTCATCTACTATCCCGACTACATCCACCCCAAAACCCATCAGGCCATCAATGCGGAAACCGC
AGCCCAAATCCTGATACGACAAAAAAATATGCAAAAAAACAACAACGGATTACATCGCGGGTGCTTTGCCAAAAAATTAG
GTAAAATCAAACAACTATATCGATCTTTCAAATAA

Protein sequence : 
MFLFSDGLQSINNNNRRKRIVKNAYIPSRGIRKIPHLSTLLPEFHIYKDGKGAEAVVGWGLRPTTHKARAFATEHQLPFI
ALEDGFLRSLGLGVSGYPPYSIVYDDIGIYYDTTRPSRLEQLILAADTIPSETLAQARQAMDFILQHHLSKYNHAPELSD
DHPLRSPSKSETVLIIDQTFGDMAIQYGGADASTFELMFQTALNENPQADIWVKTHPDVLCGKKQGYLTQLVQQHRVHLL
AEDINPISLLQNVDKVYCVTSQMGFEALLCGKPLTTFGLPWYAGWGVSDDRHPKIGSLIQTQRRAPRNLLQLFAAAYLQY
SRYLNPNTGEAGSLFDVIDYLATVKRKNDKLRGELYCVGMSLWKRAVAKPFFNVPSCRLKFISSTQKLARVKLSDDARIL
AWGNGKEAIVRFAEQHHIPLLRMEDGFIRSVGLGSNLVPPLSLVTDDMSIYFNAETPSRLEYILQNQNFDDQDFQTALKL
QKMLTENHISKYNVGSSDFTAPSTDKTVILVPGQVEDDASIRYGSPQIYRNLDLLRTVRERNPNAYIIYKPHPDVVSGNR
IGHISPDDAARYADQTAEQADILTCLQYADEIHTMTSLTGFEALLRGKKVSCYGLPFYAGWGLTQDLLPIPRRSRRLELW
QLVAGTLIYYPDYIHPKTHQAINAETAAQILIRQKNMQKNNNGLHRGCFAKKLGKIKQLYRSFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 0.0 98
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 7e-134 50
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 1e-133 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lipA YP_005892886.1 polysialic acid capsule modification protein LipA VFG0259 Protein 0.0 98
lipA YP_005892886.1 polysialic acid capsule modification protein LipA VFG0704 Protein 3e-157 58
lipA YP_005892886.1 polysialic acid capsule modification protein LipA VFG0692 Protein 3e-180 58