Gene Information

Name : lysS (NMAA_1139)
Accession : YP_005892134.1
Strain : Neisseria meningitidis WUE 2594
Genome accession: NC_017512
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase (lysine-tRNA ligase; LysRS)
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 1322632 - 1324143 bp
Length : 1512 bp
Strand : -
Note : MultiFUN-ID: 2.3.1

DNA sequence :
ATGAGCGAACAAAACCATCCGCAAACCGAGCCGCAGTTGGACGAAAACCAAATCATCGCCCTGCGCCGCGAAAAACTGCA
CAACATCCGCCAACAGCGCAACGCCTATCCCAACGACTTCAAACGCGACAGCTTCGCCGCCGATTTGCACGCCCAATACG
GCGAAATCGGCAAAGAAGAACTCGATCCGCAAGGCATTCCCGTCAAAGTGGCCGGCCGCATGATGCTGAAGCGTCAAATG
GGCAAGGCGAGCTTTGCCACCATTCAAGACGTGTCCGGGCAAATCCAGCTTTATCTGAACAACAAAGGCGTGAGCCAAGA
AGTTTTGGACGACTTCAACCATTGGGATTTGGGCGACATCGTCGGCGCGGAAGGCACTTTGTTCAAAACCAACCACGGCG
AACTGACCGTACGCGTGTCCGGCATCCGCCTGCTGTCCAAATCCCTGCGCCCTCTGCCGGACAAACATAAAGGCTTGAGC
GATCAGGAAACCAAATACCGTCAACGCTACGTCGATTTGATTGCCAACGAAGAATCGCGCAATACCTTCATCAAACGCAG
CCAAATCATCCAATCCGTGCGTAATTTTATGGTGGGCGAGCATTATCTCGAAGTCGAAACCCCGATGATGCACCCGATTC
CCGGCGGCGCGACGGCAAAACCCTTCGTTACCCATCACAATGCCTTAGATATTCCGCTTTATTTGCGAATCGCCCCCGAG
CTGTATCTGAAACGCCTGGTTGTCGGTGGTTTGGAACGCGTGTTTGAAATCAACCGCAGCTTCCGCAACGAAGGCATGTC
CGTGCGCCACAACCCCGAATTCACCATGATCGAATTCTACGAAGCCTTCTCCGACTACGAACGCATGATGCAGATGGCGG
AAGACATCATCCGCAACGCATCGCACACGGTAAACGGCACGGCAAACATCACTTACAACGGCAAAGAAGTCGATTTGGAA
AGCCCGTTTGAACGCCTGACCATTCTCGAAGCCATCAAAAAATACAATCCGCACTACACCGACGAGCAGTTGAACGATGC
GGAATGGCTGAAAAAAGAAATCGTCAAACACGGCGAAAGCCTGCCGCCGTCCCCGGGCATCGGCAGCCTGCAACTCGCGC
TGTTTGAAGGTTGCGCCGAGGGCAAGCTGTGGAATCCGACCTTCATCGTCGATTACCCGGTCGAAGTTTCCCCGTTGGCG
CGCGCTTCGGATACCAAACAAGGTCTGACCGAACGTTTCGAATTGTTCGTTGTCGGGCGCGAACTGGCAAACGGCTATTC
CGAGTTGAACGACCCCGAAGACCAAGCCGAACGCTTCAAAGCGCAAGTGGCGCAAAAAGACGCGGGCGACGACGAAGCGA
TGCACTACGATGCCGACTACATCCGCGCGATGGAGTTCGGTCTGCCGCCGACCGGCGGTTGCGGTATCGGCATCGACCGC
TTGGTAATGTTGCTGACCGATTCGCAAACCATCCGTGACGTGATTCTGTTCCCGCAGATGCGCCCCGAGTAA

Protein sequence :
MSEQNHPQTEPQLDENQIIALRREKLHNIRQQRNAYPNDFKRDSFAADLHAQYGEIGKEELDPQGIPVKVAGRMMLKRQM
GKASFATIQDVSGQIQLYLNNKGVSQEVLDDFNHWDLGDIVGAEGTLFKTNHGELTVRVSGIRLLSKSLRPLPDKHKGLS
DQETKYRQRYVDLIANEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMMHPIPGGATAKPFVTHHNALDIPLYLRIAPE
LYLKRLVVGGLERVFEINRSFRNEGMSVRHNPEFTMIEFYEAFSDYERMMQMAEDIIRNASHTVNGTANITYNGKEVDLE
SPFERLTILEAIKKYNPHYTDEQLNDAEWLKKEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIVDYPVEVSPLA
RASDTKQGLTERFELFVVGRELANGYSELNDPEDQAERFKAQVAQKDAGDDEAMHYDADYIRAMEFGLPPTGGCGIGIDR
LVMLLTDSQTIRDVILFPQMRPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-125 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_005892134.1 lysyl-tRNA synthetase (lysine-tRNA ligase; LysRS) VFG1668 Protein 6e-126 52