Gene Information

Name : lysS (NMV_0961)
Accession : YP_005878364.1
Strain : Neisseria meningitidis 8013
Genome accession: NC_017501
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase (lysine--tRNA ligase; LysRS)
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 966325 - 967836 bp
Length : 1512 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme

DNA sequence :
ATGAGCGAACAAAACCATCCGCAAACCGAGCCGCAGTTGGACGAAAACCAAATCATCGCCCTGCGCCGCGAAAAACTGCA
CAACATCCGCCAACAGCGCAACGCCTATCCCAACGACTTCAAACGCGACAGCTTCGCCGCCGATTTGCACGCCCAATACG
GCGAAATCGGCAAAGAAGAACTCGATCCGCAAGGCATTCCCGTCAAAGTGGCCGGCCGCATGATGCTGAAGCGTCAAATG
GGCAAGGCGAGCTTTGCCACTATTCAAGACGTGTCCGGGCAAATCCAGCTTTATCTGAACAACAAAGGCGTGAGCCAAGA
AGTTTTGGACGACTTCAACCATTGGGATTTGGGCGACATCGTCGGCGCGGAAGGCACTTTGTTCAAAACCAACCAGGGCG
AACTGACCGTACGCGTGTCCGGCATCCGCCTGCTGTCCAAATCCCTGCGCCCTCTGCCGGACAAACATAAAGGCTTGAGC
GATCAGGAAACCAAATACCGCCAACGCTATGTCGATTTGATTGCCAACGAAGAATCGCGCAATACCTTTATCAAACGCAG
CCAAATCATCCAATCCGTGCGTAATTTTATGGTGGGCGAGCATTATCTCGAAGTCGAAACCCCGATGATGCACCCGATTC
CCGGCGGCGCGACGGCAAAACCCTTCGTTACCCACCACAATGCCTTGGACATTCCGCTCTACCTGCGCATCGCCCCCGAG
CTGTATCTGAAACGCTTGGTTGTCGGCGGTTTGGAACGCGTGTTTGAAATCAACCGCAGCTTCCGCAACGAAGGTATGTC
TGTGCGCCATAACCCTGAATTCACCATGATCGAATTCTACGAAGCCTTCTCCGACTACGAACGCATGATGCAAATGGCGG
AAGACATCATCCGCAACGCTTCCCGCGCGGTAAACGGCACGGCAAACATCACTTACAACGGCAAAGAAGTCGATTTGGAA
AGCCCGTTCGAGCGTCTGACCATTCTCGATGCCATCAAAAAATACAATCCGCACTACACCGACGAGCAGTTGAACGATGC
GGAGTGGCTGAAAAAAGAAATCGTCAAACACGGCGAAAGCCTGCCTCCGTCTCCGGGCATCGGCAGCCTGCAACTTGCCC
TGTTTGAAGGTTGCGCCGAGGGCAAATTGTGGAACCCGACTTTCATTATCGACTACCCTGTCGAAGTGTCCCCGTTGGCA
CGCGCATCCGACAGCAAACCGGGCTTGACCGAACGCTTCGAGCTTTTCGTTGTCGGCCGCGAACTGGCAAACGGCTACTC
CGAGTTGAACGATCCGGAAGACCAAGCCGAACGCTTCAAGGCACAAGTGGCGCAAAAAGACGCGGGCGACGACGAAGCGA
TGCACTACGATGCCGACTACATCCGCGCGATGGAATTCGGCCTGCCGCCGACCGGCGGCTGCGGCATCGGCATCGACCGC
TTGGTCATGTTGCTGACCGATTCGCAAACCATCCGCGACGTGATTCTGTTTCCGCAGATGCGCCCCGAGTAG

Protein sequence :
MSEQNHPQTEPQLDENQIIALRREKLHNIRQQRNAYPNDFKRDSFAADLHAQYGEIGKEELDPQGIPVKVAGRMMLKRQM
GKASFATIQDVSGQIQLYLNNKGVSQEVLDDFNHWDLGDIVGAEGTLFKTNQGELTVRVSGIRLLSKSLRPLPDKHKGLS
DQETKYRQRYVDLIANEESRNTFIKRSQIIQSVRNFMVGEHYLEVETPMMHPIPGGATAKPFVTHHNALDIPLYLRIAPE
LYLKRLVVGGLERVFEINRSFRNEGMSVRHNPEFTMIEFYEAFSDYERMMQMAEDIIRNASRAVNGTANITYNGKEVDLE
SPFERLTILDAIKKYNPHYTDEQLNDAEWLKKEIVKHGESLPPSPGIGSLQLALFEGCAEGKLWNPTFIIDYPVEVSPLA
RASDSKPGLTERFELFVVGRELANGYSELNDPEDQAERFKAQVAQKDAGDDEAMHYDADYIRAMEFGLPPTGGCGIGIDR
LVMLLTDSQTIRDVILFPQMRPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 6e-126 52
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 1e-85 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_005878364.1 lysyl-tRNA synthetase (lysine--tRNA ligase; LysRS) VFG1668 Protein 3e-126 52