Gene Information

Name : ctrB (NMV_0073)
Accession : YP_005877670.1
Strain : Neisseria meningitidis 8013
Genome accession: NC_017501
Putative virulence/resistance : Virulence
Product : polysialic acid capsule export inner-membrane protein CtrB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 79661 - 80824 bp
Length : 1164 bp
Strand : +
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2493648; Product type t : transporter

DNA sequence :
ATGTCTGAGCAACTTCCTGTGGCAGTTGCCACTGAAACCAAAGCCGAGCGTAAAAAGCCGAAAAAGAAAAGTTGGATTAA
AAAGCTAAGCCCTTTATTTTGGGTAACGGTGATTATCCCTACGGTAATTTCGTTGGTGTATTTCGGCTTCTTCGCTTCCG
ATCGTTTTACGTCGCAATCGAGCTTTGTGGTGCGCTCGCCTAAAAGCCAATCTTCTCTCAATGGCCTGGGTGCCATTTTG
CAGGGCACAGGTTTTGCCCGTGCGCAAGATGATATTTACACGGTTGGGGAGTATATGCGTTCGCGCTCGTCTTTGGATGA
ACTGCGTAAAATCTTGCCGGTGCGTGAGTTTTATGAAACCAAAGGTGATGCGTTCAGCCGCTTTAATGGGTTTGGGTTCC
GTGGCGAGGAAGAGGCTTTTTATCAATACTATAAAAATCAGGTGATGATCAATTTTGATACGGTTTCGGGTATTTCCACG
TTGAATGTAACTTCCTTTGATGCGCTGGAATCTAAGAAAATCAATGAGGCTTTGTTAAAACAAGGTGAAGCATTGATTAA
CCAGTTGAACGATCGTGCACGTGCTGATACGGTGCGCTATGCGGAAGAAGTAGTGAAAACGGCGGCAGAGCGGGTAAAGG
AAGCCTCTCAGAATCTGACGGATTACCGGATTGCCAATGGCGTTTTTGATTTGAAAGCGCAATCGGAAGTGCAAATGGGG
TTGGTTTCCAAGCTGCAAGATGAATTGATTGTGATTCAAACCCAGCTGGATCAGGTGAAAGCAGTCACTCCGGAGAATCC
GCAGATTCCGGGTTTGCAGGCGCGTGAGCAGAGCTTGCGTAAAGAAATTGACCAACAGTTACGTGCCATTTCGGGCGGTG
GGCATTCTTCGTTGTCTAATCAGGCTGCCGAATATCAGCGTGTGTATTTGGAAAACCAGTTGGCAGAGCAGCAGTTGGCA
GCCGCCATGACTTCTTTGGAAAGTGCCAAGGTTGAAGCAGACCGTCAGCAGCTTTATTTGGAAGTGATCTCGCAACCGAG
CCTGCCGGATTTGGCACATGAGCCTAAACGGTTATACAACATTGTTGCCACTCTGATTATCGGCTTGATGGTTTATGGTA
TTTTGAGCCTGTTGACTGCCAGCATTCGTGAGCATAAAAACTGA

Protein sequence :
MSEQLPVAVATETKAERKKPKKKSWIKKLSPLFWVTVIIPTVISLVYFGFFASDRFTSQSSFVVRSPKSQSSLNGLGAIL
QGTGFARAQDDIYTVGEYMRSRSSLDELRKILPVREFYETKGDAFSRFNGFGFRGEEEAFYQYYKNQVMINFDTVSGIST
LNVTSFDALESKKINEALLKQGEALINQLNDRARADTVRYAEEVVKTAAERVKEASQNLTDYRIANGVFDLKAQSEVQMG
LVSKLQDELIVIQTQLDQVKAVTPENPQIPGLQAREQSLRKEIDQQLRAISGGGHSSLSNQAAEYQRVYLENQLAEQQLA
AAMTSLESAKVEADRQQLYLEVISQPSLPDLAHEPKRLYNIVATLIIGLMVYGILSLLTASIREHKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ctrB NP_273136.1 capsule polysaccharide export inner-membrane protein Not tested IHT-A Protein 5e-158 100

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ctrB YP_005877670.1 polysialic acid capsule export inner-membrane protein CtrB VFG0256 Protein 2e-158 100
ctrB YP_005877670.1 polysialic acid capsule export inner-membrane protein CtrB VFG0686 Protein 5e-101 62
ctrB YP_005877670.1 polysialic acid capsule export inner-membrane protein CtrB VFG0698 Protein 5e-101 62
ctrB YP_005877670.1 polysialic acid capsule export inner-membrane protein CtrB VFG2565 Protein 1e-63 43