Gene Information

Name : ctrA (NMV_0072)
Accession : YP_005877669.1
Strain : Neisseria meningitidis 8013
Genome accession: NC_017501
Putative virulence/resistance : Virulence
Product : polysialic acid capsule export outer-membrane lipoprotein CtrA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 78471 - 79646 bp
Length : 1176 bp
Strand : +
Note : 'Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1371768, 2493648; Product type t : transporter'

DNA sequence :
GTGTTTAAAGTGAAATTTTATATTCGTCACGCAGTATTATTATTGTGTGGAAGTTTAATTGTAGGATGCTCTGCGATTCC
TTCATCAGGCCCCAGCGCAAAAAAAATTGTCTCTTTAGGGCAACAATCTGAAGTTCAAATTCCTGAAGTGGAGCTGATTG
ATGTGAATCATACGGTTGCTCAGTTATTATATAAGGCTCAGATAAATCAGTCATTCACTCAGTTTGGCGATGGTTATGCT
TCGGCTGGTACGCTAAATATTGGTGATGTATTGGATATTATGATTTGGGAAGCGCCGCCGGCAGTATTGTTTGGTGGTGG
CCTTTCTTCGATGGGCTCGGGTAGTGCGCATCAAACTAAGTTGCCAGAGCAGTTGGTCACGGCACGTGGTACGGTTTCTG
TGCCGTTTGTTGGCGATATTTCGGTGGTCGGTAAAACGCCTGGTCAGGTTCAGGAAATTATTAAAGGCCGCCTGAAAAAA
ATGGCCAATCAGCCACAAGTGATGGTGCGTTTGGTGCAGAATAATGCGGCGAATGTGTCGGTGATTCGTGCTGGGAATAG
TGTGCGTATGCCGCTGACGGCAGCCGGTGAGCGTGTGTTGGATGCGGTGGCTGCGGTAGGTGGTTCAACGGCAAATGTGC
AGGATACGAATGTGCAGCTGACACGTGGCAATGTAGTACGAACTGTTGCCTTGGAAGATTTAGTTGCAAATCCGCGACAA
AATATTTTGCTGCGTCGCGGTGATGTGGTTACCATGATTACCAATCCCTATACCTTTACGTCTATGGGTGCGGTGGGGAG
AACACAAGAAATCGGTTTTTCAGCCAGAGGCTTATCGCTTTCTGAAGCCATTGGCCGTATGGGCGGTTTGCAAGATCGCC
GTTCTGATGCGCGTGGTGTGTTTGTGTTCCGCTATACGCCATTGGTGGAATTGCCGGCAGAACGTCAGGATAAATGGATT
GCTCAAGGTTATGGCAGTGAGGCAGAGATTCCAACGGTATATCGTGTGAATATGGCTGATGCGCATTCGCTATTTTCTAT
GCAGCGCTTTCCTGTGAAGAATAAAGATGTATTGTATGTGTCGAATGCGCCGTTGGCTGAAGTGCAGAAATTTTTGTCGT
TTGTGTTCTCGCCGGTTACCAGTGGCGCGAACAGTATTAATAATTTAACTAATTAA

Protein sequence :
MFKVKFYIRHAVLLLCGSLIVGCSAIPSSGPSAKKIVSLGQQSEVQIPEVELIDVNHTVAQLLYKAQINQSFTQFGDGYA
SAGTLNIGDVLDIMIWEAPPAVLFGGGLSSMGSGSAHQTKLPEQLVTARGTVSVPFVGDISVVGKTPGQVQEIIKGRLKK
MANQPQVMVRLVQNNAANVSVIRAGNSVRMPLTAAGERVLDAVAAVGGSTANVQDTNVQLTRGNVVRTVALEDLVANPRQ
NILLRRGDVVTMITNPYTFTSMGAVGRTQEIGFSARGLSLSEAIGRMGGLQDRRSDARGVFVFRYTPLVELPAERQDKWI
AQGYGSEAEIPTVYRVNMADAHSLFSMQRFPVKNKDVLYVSNAPLAEVQKFLSFVFSPVTSGANSINNLTN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ctrA NP_273135.1 capsule polysaccharide export outer membrane protein Not tested IHT-A Protein 4e-177 100

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ctrA YP_005877669.1 polysialic acid capsule export outer-membrane lipoprotein CtrA VFG0255 Protein 2e-177 100
ctrA YP_005877669.1 polysialic acid capsule export outer-membrane lipoprotein CtrA VFG0699 Protein 2e-100 53
ctrA YP_005877669.1 polysialic acid capsule export outer-membrane lipoprotein CtrA VFG0687 Protein 2e-100 53
ctrA YP_005877669.1 polysialic acid capsule export outer-membrane lipoprotein CtrA VFG2566 Protein 6e-72 42