Gene Information

Name : siaA (NMV_0071)
Accession : YP_005877668.1
Strain : Neisseria meningitidis 8013
Genome accession: NC_017501
Putative virulence/resistance : Virulence
Product : UDP-N-acetylglucosamine 2-epimerase (uridine diphosphate-N-acetylglucosamine-2-epimerase; UDP-GlcNAc-2-epimerase)
Function : -
COG functional category : -
COG ID : -
EC number : 5.1.3.14
Position : 77195 - 78328 bp
Length : 1134 bp
Strand : -
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7830552; Product type e : enzyme

DNA sequence : 
ATGAAAAGAATTCTTTGCATTACAGGTACCAGAGCCGACTTCGGCAAGCTAAAACCTTTATTAGCCTATATTGAAAATCA
CCCAGACCTTGAATTGCATTTGATTGTAACTGGTATGCATATGATGAAAACATATGGCAGAACCTACAAGGAAGTAACTC
GAGAAAACTATCAACATACATATCTGTTTTCAAATCAAATCCAAGGTGAACCAATGGGTGCCGTTTTAGGCAATACCATT
ACGTTTATCTCTCGTCTATCTGATGAAATTGAACCTGATATGGTCATGATTCACGGCGACCGTTTAGAAGCACTAGCAGG
CGCAGCTGTAGGTGCATTAAGCAGCCGTTTAGTTTGCCATATCGAAGGTGGTGAACTATCTGGTACAGTAGATGACTCCA
TTCGTCATTCTATTAGTAAACTTTCTCATATCCACTTGGTAGCAAATGAACAAGCTGTCACTCGCCTAGTGCAAATGGGA
GAAAAAAGAAAGCATATTCACATCATCGGCTCCCCCGATTTAGATGTTATGGCCTCTTCCACCCTCCCATCCTTAGAAGA
AGTCAAAGAATATTACGGTTTACCATACGAAAATTATGGTATTTCTATGTTTCACCCCGTGACTACAGAAGCACATTTAA
TGCCACAATATGCGGCCCAATATTTCAAAGCATTAGAATTAAGTGGCCAAAATATCATTAGCATCTACCCTAATAATGAC
ACTGGCACTGAAAGTATTCTGCAAGAATTATTAAAATATCAATCTGATAAATTTATTGCATTTCCTTCCATTCGATTTGA
ATATTTTTTAGTCTTATTGAAACATGCTAAATTTATGGTCGGCAACTCAAGTGCAGGTATTAGAGAAGCTCCTCTCTACG
GTGTCCCTTCAATTGATGTTGGTACACGCCAAAGTAACCGCCATATGGGAAAATCTATTATTCATACAGATTATGAAACT
AAAAATATCTTTGATGCGATTCAACAAGCATGCAGTTTAGGCAAATTTGAAGCAGATGATACCTTTAATGGCGGAGATAC
TCGCACCAGCACAGAAAGATTTGCTGAAGTAATCAACAATCCTGAAACGTGGAATGTTTCTGCTCAAAAACGTTTTATCG
ATTTGAATCTTTAA

Protein sequence : 
MKRILCITGTRADFGKLKPLLAYIENHPDLELHLIVTGMHMMKTYGRTYKEVTRENYQHTYLFSNQIQGEPMGAVLGNTI
TFISRLSDEIEPDMVMIHGDRLEALAGAAVGALSSRLVCHIEGGELSGTVDDSIRHSISKLSHIHLVANEQAVTRLVQMG
EKRKHIHIIGSPDLDVMASSTLPSLEEVKEYYGLPYENYGISMFHPVTTEAHLMPQYAAQYFKALELSGQNIISIYPNND
TGTESILQELLKYQSDKFIAFPSIRFEYFLVLLKHAKFMVGNSSAGIREAPLYGVPSIDVGTRQSNRHMGKSIIHTDYET
KNIFDAIQQACSLGKFEADDTFNGGDTRTSTERFAEVINNPETWNVSAQKRFIDLNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
synX NP_273134.1 polysialic acid capsule biosynthesis protein SynX Not tested IHT-A Protein 6e-174 100

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
siaA YP_005877668.1 UDP-N-acetylglucosamine 2-epimerase (uridine diphosphate-N-acetylglucosamine-2-epimerase; UDP-GlcNAc-2-epimerase) VFG0254 Protein 2e-174 100